Ma, Weimin et al. published their research in Organic Chemistry Frontiers in 2019 | CAS: 24410-61-5

7-Fluorobenzofuran (cas: 24410-61-5) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 7-Fluorobenzofuran

Direct construction of 2,3-unsubstituted benzofurans and benzothiophenes via a metal-free catalyzed intramolecular Friedel-Crafts reaction was written by Ma, Weimin;Huang, Jiawei;Huang, Xianyu;Meng, Shulin;Yang, Zhengwei;Li, Chao;Wang, Yue;Qi, Ting;Li, Baolin. And the article was included in Organic Chemistry Frontiers in 2019.Recommanded Product: 7-Fluorobenzofuran This article mentions the following:

A highly effective and straightforward method for the construction of 2,3-unsubstituted benzofurans and benzothiophenes such as I [R = 7-F, 6-Me, 5-OMe, etc.; X = O, S] by the intramol. Friedel-Crafts reaction was developed. This phosphoric acid-catalyzed method exhibited good functional group tolerance for both electron-withdrawing groups and electron-donating groups. Successfully synthesized benzofuran and benzothiophene derivatives with various substituents, and the yield was up to 94%. The development of this reaction provided a simple and efficient strategy for the construction of benzofuran and benzothiophene skeleton compounds In the experiment, the researchers used many compounds, for example, 7-Fluorobenzofuran (cas: 24410-61-5Recommanded Product: 7-Fluorobenzofuran).

7-Fluorobenzofuran (cas: 24410-61-5) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 7-Fluorobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

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Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 24410-61-5, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 24410-61-5, in my other articles.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 24410-61-5, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 24410-61-5, Name is 7-Fluorobenzofuran, molecular formula is C8H5FO

The first example of sole direct C-H bond arylation of benzo[b]furans with aryl chlorides was achieved catalyzed by a well-defined NHC-Pd(II)-Im complex. Under the suitable conditions, all reactions involving kinds of benzo[b]furans and (hetero)aryl chlorides proceeded well to give the desired C2-arylated benzo[b]furans in sole regioselectivity in acceptable to high yields, providing an efficient and economic pathway for the direct C2-H bond arylation of benzo[b]furans.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 24410-61-5, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 24410-61-5, in my other articles.

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H578O – PubChem

The important role of 7-Fluorobenzofuran

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C8H5FO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 24410-61-5

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C8H5FO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 24410-61-5, Name is 7-Fluorobenzofuran, molecular formula is C8H5FO

The present invention relates to novel hydantoin derivatives, processes for producing said hydantoin derivatives, pharmaceutical compositions containing at least one of said hydantoin derivatives as aldose reductase inhibitors and novel intermediate compounds in the synthesis of said hydantoin derivatives. The present invention is based on the selection of a hydantoin which is bonded by a sulfonyl group to various substituents at the 1-position of the hydantoin skeleton. The compounds of the present invention have a strong inhibitory activity against aldose reductase. These compounds are extremely useful for the treatment and/or prevention of various forms of diabetic complications based on the accumulation of polyol metabolites.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C8H5FO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 24410-61-5

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H575O – PubChem

New explortion of 7-Fluorobenzofuran

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24410-61-5, Name is 7-Fluorobenzofuran, belongs to benzofurans compound, is a common compound. category: benzofuranIn an article, once mentioned the new application about 24410-61-5.

The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof. The compound has a superior TRPA1 antagonist activity, and can provide a medicament useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H574O – PubChem

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24410-61-5, As the paragraph descriping shows that 24410-61-5 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24410-61-5,7-Fluorobenzofuran,as a common compound, the synthetic route is as follows.

Step 1 Preparation of 7-fluorobenzo[b]furan-2-ylsulfonyl chloride. Starting from 7-fluorobenzo[b]furan (10.4 g), the objective compound (5.7 g) was obtained in a manner similar to Step 1 of Example 91.

24410-61-5, As the paragraph descriping shows that 24410-61-5 is playing an increasingly important role.

Reference£º
Patent; Mochida Pharmaceutical Co., Ltd.; US5004751; (1991); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

Brief introduction of 24410-61-5

The synthetic route of 24410-61-5 has been constantly updated, and we look forward to future research findings.

24410-61-5, 7-Fluorobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step 1 Preparation of 2,3-dibromo-2,3-dihydro-7-fluorobenzo[b]furan. To a solution of 7-fluorobenzo[b]furan (16 g) in carbon tetrachloride (40 ml) was added dropwise a solution of bromine (22 g) in carbon disulfide (40 ml) at -30 C. and the solution was stirred for 1 hour. At room temperature, the formed precipitate was separated by filtration to give 34.4 g of the objective compound. IR (KBr, cm-1): 1634, 1601, 1489, 1459, 1279, 1179 NMR (CDCl3, ppm): 5.74 (1H, d, J=1.3 Hz),

The synthetic route of 24410-61-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Mochida Pharmaceutical Co., Ltd.; US5004751; (1991); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem