501892-90-6, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 501892-90-6, Name is Methyl 3-bromobenzofuran-5-carboxylate, molecular formula is C10H7BrO3. In a Chapter, authors is Pike, Kurt G.£¬once mentioned of 501892-90-6
Inhibitors of the fibroblast growth factor receptor
Signaling through the fibroblast growth factor receptor (FGFR) tyrosine kinase is crucial to a number of key pharmacological processes; however, dysregulation of this signaling is observed with a number of different cancers suggesting that inhibition of FGFR may provide an important therapeutic agent in the treatment of cancers. This chapter provides an overview of the development of FGFR inhibitors beginning with the identification of nonselective FGFR inhibitors, then describing the medicinal chemistry optimization resulting in the delivery of a number of highly selective FGFR inhibitors, some of which are currently being assessed in clinical trials. The development of isoform selective FGFR inhibitors as well as covalent inhibitors and inhibitors of the inactive form of FGFR are also described.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.501892-90-6. In my other articles, you can also check out more blogs about 501892-90-6
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3974O – PubChem