Analyzing the synthesis route of 76429-69-1

76429-69-1 5-Chloro-2,3-dihydrobenzofuran 592964, abenzofuran compound, is more and more widely used in various.

76429-69-1, 5-Chloro-2,3-dihydrobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

76429-69-1, a) To a stirred and cooled mixture of 32 nil of sulfuric acid and 14 ml of water there were added 17 g of 2,3-dihydro-5-chlorobenzofuran, while keeping the temperature at 25 C. After cooling to 0 C., there were added dropwise 14 ml of nitric acid. Stirring and cooling at 0 C. was continued for 44 hours. The reaction mixture was diluted with water (temp. <10 C.) and stirred for 15 min. The precipitate was filtered off, washed with water and recrystallized from a mixture of ethyl acetate and hexane (30:70), yielding 8.9 g (40.5%) of 5-chloro-2,3-dihydro-7-nitrobenzofuran (interm. 3). 76429-69-1 5-Chloro-2,3-dihydrobenzofuran 592964, abenzofuran compound, is more and more widely used in various. Reference£º
Patent; Janssen Pharmaceutica N.V.; US5407961; (1995); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem