Month: November 2022

Choi, Sang Won published the artcileAnalysis of functional constituents in mulberry (Morus alba L.) twigs by different cultivars, producing areas, and heat processings, Synthetic Route of 56317-21-6, the publication is Preventive Nutrition and Food Science (2013), 18(4), 256-262, database is CAplus and MEDLINE.

Four functional constituents, oxyresveratrol 3′-O-β-D-glucoside (ORTG), oxyresveratrol (ORT), t-resveratrol (RT), and moracin (MC) were isolated from the ethanolic extract of mulberry (Morus alba L.) twigs by a series of isolation procedures, including solvent fractionation, and silica-gel, ODS-A, and Sephadex LH-20 column chromatogs. Their chem. structures were identified by NMR and FABMS spectral anal. Quant. changes of four phytochems. in mulberry twigs were determined by HPLC according to cultivar, producing area, and heat processing. ORTG was a major abundant compound in the mulberry twigs, and its levels ranged from 23.7 to 105.5 mg% in six different mulberry cultivars. Three other compounds were present in trace amounts (<1 mg/100 g) or were not detected. Among mulberry cultivars examined, “Yongcheon” showed the highest level of ORTG, whereas “Somok” had the least ORTG content. Levels of four phytochems. in the mulberry twigs harvested in early Sept. were higher than those harvested in early July. Levels of ORTG and ORT in the “Cheongil” mulberry twigs produced in the Uljin area were higher than those produced in other areas. Generally, levels of ORTG and ORT in mulberry twigs decreased with heat processing, such as steaming, and microwaving except roasting, whereas those of RT and MC did not considerably vary according to heat processing. These results suggest that the roasted mulberry twigs may be useful as potential sources of functional ingredients and foods.

Preventive Nutrition and Food Science published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Synthetic Route of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Ghoneim, M. M. published the artcileInfrared spectra of some derivatives of phenolphthalein and sulfonphthalein, Application In Synthesis of 596-01-0, the publication is Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical (1979), 18A(4), 349-50, database is CAplus.

The comparison of the IR of phenolphthalein, sulfonphthalein and their derivatives, observed in KBr, indicates that the phenolphthaleins exist mainly in the lactone form; sulfonphthaleins have the quinone-like structure. This behavior is attributed to the higher tendency of sulfonphthalein to form the sulfonate ion than the phenolphthalein to attain the carboxylic structure.

Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Tada, Atsuko published the artcileExamination of original plant of mulberry bark extract, a natural food additive, based on composition of the constituents, Related Products of benzofurans, the publication is Shokuhin Eiseigaku Zasshi (2011), 52(4), 258-264, database is CAplus and MEDLINE.

Mulberry bark extract, a natural food additive, is described as a “root bark extract from Morus bombycis” (Japanese name: Yamaguwa) in the Notice (1996) relating to existing food additives used in Japan. The results of analyses by LC/UV and LC/MS suggested that the Mulberry bark extract products that were tested were actually made from the root bark of Morus alba (Japanese name: Maguwa) or its hybrid species, because the compositions of the constituents in the products are more similar to those in the extracts of the dried root bark of M. alba and hybrid species that are cultivated in Japan than to those of M. bombycis. In addition, the constituents of the food additive products were different from those of the natural medicine Mori Cortex products (‘Souhakuhi’ in Japanese) made from the root bark of mulberry grown in China, and which is described as being derived from M. alba in the Japanese pharmacopoeia. These results were also corroborated by Principal Component Anal. using the peak areas of LC/MS anal. as explanatory variables. After this study, it was decided that Mulberry bark extract is one of the existing food additives that should be excluded from the list this year in Japan.

Shokuhin Eiseigaku Zasshi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C10H15ClO3S, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kakiya, Hirotada published the artcileReaction of gem-dibromocyclopropanes or iodobenzofuran with trialkylmanganate, Category: benzofurans, the publication is Tetrahedron (2000), 56(15), 2131-2137, database is CAplus.

Treatment of gem-dibromocyclopropanes with trialkylmanganate, derived from manganese(II) chloride and three equivalent of Grignard reagent or alkyllithium, followed by an addition of electrophiles provided dialkylated cyclopropanes in good yields. It was found that the reaction of gem-dibromocyclopropanes with alkylmagnesium halide proceeded in the presence of a catalytic amount of manganese(II) chloride. The use of iodobenzofuran in place of gem-dibromocyclopropane gave a ring opening product, 2-alkenylphenol.

Tetrahedron published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Category: benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kortman, Gregory D. published the artcileCopper-Catalyzed Hydroarylation of Internal Alkynes: Highly Regio- and Diastereoselective Synthesis of 1,1-Diaryl, Trisubstituted Olefins, HPLC of Formula: 69626-75-1, the publication is ACS Catalysis (2017), 7(9), 6220-6224, database is CAplus.

The copper-catalyzed hydroarylation of internal, unsym. alkynes is presented. Trisubstituted alkenes are obtained as single diastereomers in good to excellent yields and excellent regioselectivities. The scope of the reaction is presented with respect to alkyne and aryl iodide coupling partners. Initial mechanistic experiments indicate a hydrocupration event followed by a two-electron oxidative addition/reductive elimination pathway.

ACS Catalysis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, HPLC of Formula: 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Hao, Mimi published the artcileBioactive flavonoids and stilbenes from the leaf of Morus alba var. multicaulis, SDS of cas: 56317-21-6, the publication is Fitoterapia (2021), 105018, database is CAplus and MEDLINE.

Twenty-two flavonoids and stilbenes (1-22) were obtained from the leaf of Morus alba var. multicaulis. Among them, morusalbanosides A (1), B1 (2), and B2 (3) were new compounds Moreover, compounds 1, 3, 4-11, 15-18, and 22 displayed inhibitory effects on triglyceride (TG) accumulation in HepG2 cells in a concentration dependent manner. Furthermore, compounds 1, 3, 11, and 22 could activate the phosphorylation of AMP-activated protein kinase α (AMPKα), reduce the synthesis of TG by inhibiting the expression of fatty acid synthase (FAS) and stearoyl-CoA desaturase 1 (SCD1). While, only compounds 1 and 11 could promote the phosphorylation of acetyl-CoA carboxylase 1 (ACC1) and accelerate the oxidation of fatty acids by up-regulating carnitine palmitoyltransferase 1A (CPT1A). In brief, this study found that most of the researched flavonoids and stilbenes could regulate TG metabolism in vitro. They might play the role by up-regulating phosphorylation of AMPKα, inhibiting TG biosynthesis, and promoting the oxidation of fatty acids.

Fitoterapia published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, SDS of cas: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Liu, Ai-hong published the artcileChemical constituents occurring in roots of Artocarpus nanchuanensis, HPLC of Formula: 56317-21-6, the publication is Zhongguo Shiyan Fangjixue Zazhi (2014), 20(22), 91-94, database is CAplus.

The chem. constituents of roots of Artocarpus nanchuanensis were studied. The constituents were isolated from the Et acetate portion of 95% ethanol extraction of A. nanchuanensis roots by column chromatog. over silica gel, Diaion HP20 macroreticular resin, MCI CHP 20P gel, Sephadex LH-20 gel, ODS gel, etc. Their structures were elucidated by anal. of phys. chem. properties and spectral data. Nine compounds were isolated and their structures were identified as p-hydroxybenzaldehyde (1), 2,4-dihydroxybenzoic acid (2), p-coumaric acid (3), (+)-catechin (4), (E)-ferulic acid Me ester (5), p-E-hedroxycinnamic acid Me ester (6), norartocarpetin (7), trans-oxyresveratrol (8) and moracin M (9). Compounds 1, 2, 5 and 6 were isolated from Moraceae for the first time. Compound 3 was firstly reported in the genus Artocarpus, and compounds 7-9 were characterized in A. nanchuanensis for the first time.

Zhongguo Shiyan Fangjixue Zazhi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, HPLC of Formula: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Matsuzawa, Tsubasa published the artcileTransition-Metal-Free Synthesis of N-Arylphenothiazines through an N- and S-Arylation Sequence, Quality Control of 69626-75-1, the publication is Organic Letters (2021), 23(6), 2347-2352, database is CAplus and MEDLINE.

An efficient synthetic method of N-arylphenothiazines, e.g., I, from o-sulfanylanilines under transition-metal-free conditions is disclosed. An N- and S-arylation sequence of o-sulfanylanilines enabled the authors to synthesize a wide variety of N-arylphenothiazines. In particular, one-pot synthesis of N-arylphenothiazines was accomplished from easily available modules through preparation of o-sulfanylanilines by thioamination of aryne intermediates and following N- and S-arylation sequence.

Organic Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Quality Control of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Vo, Quan V. published the artcileThe radical scavenging activity of moracins: theoretical insights, Related Products of benzofurans, the publication is RSC Advances (2020), 10(60), 36843-36848, database is CAplus and MEDLINE.

Moracins are natural products that have been isolated from different plants such as Artocarpus heterophyllus, Cassia fistula, Morus alba, and Morus mesozygia. Studies showed that moracins may have various advantageous physiol. effects such as anticancer, anti-inflammatory, anticholinesterase and particularly antioxidant activities. Most of these bioactivities have not been studied systematically. In this study, the radical scavenging of a typical moracin (moracin M, MM) against HO and HOO radicals was evaluated by thermodn. and kinetic calculations in the gas phase as well as in water and pentyl ethanoate solvents. It was found that the overall rate constants for the HO radical scavenging in the gas phase and the physiol. environments are in the range of 10¹¹ to 10¹⁰ M^-1 s^-1, resp. For the HOO + MM reaction the rate constants are 4.10 x 10⁷ and 3.80 x 10⁴ M^-1 s^-1 in the polar and lipid media, resp. It is important to notice that the single electron transfer pathway of the anion state (MM-O6′-) dominated the HOO radical scavenging in the aqueous solution, whereas in lipid medium the neutral MM exerted its activity by the formal hydrogen transfer mechanism. The HOO radical scavenging of MM is comparable to that of Trolox in lipid medium, whereas it is 315.4 times more active in the polar environment.

RSC Advances published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C20H18BrN3, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Royer, Mariana published the artcileSecondary metabolites of Bagassa guianensis Aubl. wood: A study of the chemotaxonomy of the Moraceae family, HPLC of Formula: 56317-21-6, the publication is Phytochemistry (Elsevier) (2010), 71(14-15), 1708-1713, database is CAplus and MEDLINE.

In order to explain the durability of the Moraceae plant family, phytochem. of Bagassa guianensis was performed. Et acetate extract was obtained from the heartwood and 18 secondary metabolites were isolated, including 6 moracins [6-O-methyl-moracin M, 6-O-methyl-moracin N and moracin Z; previously identified: moracin M, moracin N and moracin P], 8 stilbenoids [presently identified: (-)-epialboctalol and arachidin 4; previously identified: alboctalol, trans-resveratrol, arachidin 2, trans-oxyresveratrol and artogomezianol], 3 previously identified flavonoids, steppogenin, katuranin and dihydromorin, β-sitosterol and resorcinol. Previous studies suggest that stilbenoids are responsible for the natural durability of wood. This study has determined that B. guianensis is closely related to Morus sp. in phylogeny and should be included in the Moreae sensu stricto tribe of the Moraceae family.

Phytochemistry (Elsevier) published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, HPLC of Formula: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem