Day: January 20, 2022

An article Conversion of Aryl Aldehydes to Benzyl Iodides and Diarylmethanes by H3PO3/I-2 WOS:000618540600061 published article about FRIEDEL-CRAFTS ALKYLATION; CYCLIZATION; HALIDES; ARENES; ACID; NUCLEOPHILES; ALCOHOLS; BROMIDES in [Lv, Fang; Xiao, Jing; Xiang, Junchun; Guo, Fengzhe; Tang, Zi-Long] Hunan Univ Sci & Technol, Minist Educ, Key Lab Theoret Organ Chem & Funct Mol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China; [Han, Li-Biao] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058565, Japan in 2021, Cited 61. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Computed Properties of C8H6O2

For the first time, H3PO3 was used as both the reducing reagent and the promotor in the reductive benzylation reactions with aryl aldehydes. By using a H3PO3/I-2 combination, various aromatic aldehydes underwent iodination reactions and Friedel-Crafts type reactions with arenes via benzyl iodide intermediates, readily producing benzyl iodides and diarylmethanes in good yields. Intramolecular cyclization reactions also took place, giving the corresponding cyclic compounds. This new strategy features easy-handling, low-cost, and metal-free conditions.

Computed Properties of C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

SDS of cas: 87-41-2. In 2020 TOXICOL IN VITRO published article about PEROXIDE-INDUCED DAMAGE; OXIDATIVE STRESS; 3-SUBSTITUTED ISOCOUMARINS; CELLS; CHEMISTRY in [Teixeira, Aniely dos Reis; Ribeiro, Iara Mariana Lellis; Oliveira, Laser Antonio Machado; Nogueira, Katiane de Oliveira Pinto Coelho] Univ Fed Ouro Preto, Dept Biol Sci, Neurobiol & Biomat Lab, Ouro Preto, MG, Brazil; [Teixeira, Robson Ricardo; Pereira, Wagner Luiz] Univ Fed Vicosa, Dept Chem, Vicosa, MG, Brazil; [Manhabosco, Taise Matte; de Brito, Ana Carolina Ferreira] Univ Fed Ouro Preto, Dept Phys, REDEMAT, Ouro Preto, MG, Brazil in 2020, Cited 52. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

The isobenzofuran-1(3H)-ones (phthalides) exhibit various biological activities, including antioxidant activity on reactive oxygen species (ROS). An excess of ROS that cannot be naturally contained by cellular enzymatic systems is called redox imbalance, which damage cell membranes, proteins, and DNA, thereby possibly triggering neuronal death in several neurodegenerative diseases. Considering our ongoing efforts to find useful compounds to control redox imbalance, herein we evaluated the antioxidant activity of two phtalides (compounds 3 and 4), using primary cultures of hippocampal neurons. Spectrophotometric assays showed that compound 3 significantly reduced (p <= 0.05) ROS levels and lipid peroxidation compared to the control treatment, while compound 4 was unable at any of the tested concentrations. Despite their structural similarity, these compounds behave differently in the intracellular environment, which was reliably corroborated by the determination of oxidation potentials via cyclic voltammetry. It was demonstrated that compound 3 presents a lower oxidation potential. The combination of the mentioned methods allowed us to find a strong correlation between the chemical structure of compounds and their biological effects. Taking together, the results indicate that compound 3 presents desirable characteristics to act as a candidate pharmacological agent for use in the prevention and treatment of neurodegenerative diseases. SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Teixeira, AD; Teixeira, RR; Ribeiro, IML; Pereira, WL; Manhabosco, TM; de Brito, ACF; Oliveira, LAM; Nogueira, KDPC or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

I found the field of Chemistry very interesting. Saw the article Squaramide-Catalyzed Asymmetric Intramolecular Oxa-Michael Reaction of alpha,beta-Unsaturated Carbonyls Containing Benzyl Alcohol: Construction of Chiral 1-Substituted Phthalans published in 2021. Application In Synthesis of Isobenzofuran-1(3H)-one, Reprint Addresses Kim, SG (corresponding author), Kyonggi Univ, Coll Nat Sci, Dept Chem, Suwon 16227, South Korea.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Organocatalytic enantioselective intramolecular oxa-Michael reactions of benzyl alcohol bearing alpha,beta-unsaturated carbonyls as Michael acceptors are presented herein. Using cinchona squaramide-based organocatalyst, enones as well as alpha,beta-unsaturated esters containing benzyl alcohol provided their corresponding 1,3-dihydroisobenzofuranyl-1-methylene ketones and 1,3-dihydroisobenzofuranyl-1-methylene esters in excellent yields with high enantioselectivities. In addition, enantioenriched 1,3-dihydroisobenzofuranyl-1-methylene ketone could be obtained from the Wittig/oxa-Michael reaction cascade of 1,3-dihydro-2-benzofuran-1-ol.

Application In Synthesis of Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

COA of Formula: C8H6O2. In 2019 FITOTERAPIA published article about RESAZURIN in [Intaraudom, Chakapong; Bunbamrung, Nantiya; Dramae, Aibrohim; Boonruangprapa, Tanapong; Pittayakhajonwut, Pattama] Natl Sci & Technol Dev Agcy, Natl Ctr Genet Engn & Biotechnol BIOTEC, Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathum Thani, Thailand; [Punyain, Wikorn] Naresuan Univ, Fac Sci, Dept Chem, Phitsanulok 65000, Thailand in 2019, Cited 12. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Fourteen new compounds including thirteen drimane – phthalide derivatives (fendlerals A – C, fendlerins A – D, fendlerols A – B, fendleric acids A – C, fendlerinine G) and one terphenyl derivative (fendleryl E) along with eight known compounds, fendlerinine A, rickenyls C – D, fendleryls C – D, atromentin, tetramethyl atromentin, and ( +/- )-microsphaerophthalide F, were isolated from the wood fungus Hypoxylon fendleri BCC32408. Compared with the prior work, the results indicated the agitation effect on the production of bioactive drimane – phthalides. The chemical structures were determined based upon spectroscopic analyses and the absolute configurations were verified by comparison of the ECD spectral data with the calculated ECD spectra of the related compounds. Compounds 1-3 exhibited antimicrobial activity against Plasmodium falciparum (IC50 4.15-4.39 mu M), Colletotrichum capsici (MIC 6.25-12.5 mu g/mL), and Bacillus cereus (MIC 1.56-3.13 mu g/mL). All tested compounds displayed broad cytotoxicity against cancerous (MCF-7, KB, and NCI-H187) and non-cancerous (Vero) cells.

COA of Formula: C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Name: Isobenzofuran-1(3H)-one. I found the field of Plant Sciences; Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Synthesis of phthalide derivatives and evaluation on their antiplatelet aggregation and antioxidant activities published in 2020, Reprint Addresses Liang, S (corresponding author), Shanghai Univ Tradit Chinese Med, Innovat Res Inst Tradit Chinese Med, Shanghai 201203, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

As part of our continuing efforts to discover structurally interesting bioactive phthalide derivatives, 23 of them with a structure incorporating thiophen or halogens were designed and synthesized, 17 of which are previously unreported. In vitro antiplatelet aggregation activity screening showed that 14b could significantly inhibit platelet aggregation induced by arachidonic acid, compared with edaravone (p < 0.01). Meanwhile, oxidative damage models using SH-SY5Y and PC12 cells induced by H2O2 were built to evaluate the antioxidant activity of the phthalide derivatives. In SH-SY5Y cells, compared with aspirin, 1a significantly increased the relative cell survival rate (p < 0.05). Compared with edaravone, 1a (p < 0.01) and 15b (p < 0.05) significantly increased the relative cell survival rate. In PC12 cells, 1a (p < 0.01), 15b (p < 0.01), and 12a (p < 0.05) remarkably increased the cell survival rate compared with edaravone. The present study identified lead structures to develop potential anti-ischemic stroke agents. Welcome to talk about 87-41-2, If you have any questions, you can contact Fang, X; Ma, Q; Zhang, KX; Yao, SY; Feng, Y; Jin, YS; Liang, S or send Email.. Name: Isobenzofuran-1(3H)-one

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem