I found the field of Chemistry very interesting. Saw the article Squaramide-Catalyzed Asymmetric Intramolecular Oxa-Michael Reaction of alpha,beta-Unsaturated Carbonyls Containing Benzyl Alcohol: Construction of Chiral 1-Substituted Phthalans published in 2021. Application In Synthesis of Isobenzofuran-1(3H)-one, Reprint Addresses Kim, SG (corresponding author), Kyonggi Univ, Coll Nat Sci, Dept Chem, Suwon 16227, South Korea.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one
Organocatalytic enantioselective intramolecular oxa-Michael reactions of benzyl alcohol bearing alpha,beta-unsaturated carbonyls as Michael acceptors are presented herein. Using cinchona squaramide-based organocatalyst, enones as well as alpha,beta-unsaturated esters containing benzyl alcohol provided their corresponding 1,3-dihydroisobenzofuranyl-1-methylene ketones and 1,3-dihydroisobenzofuranyl-1-methylene esters in excellent yields with high enantioselectivities. In addition, enantioenriched 1,3-dihydroisobenzofuranyl-1-methylene ketone could be obtained from the Wittig/oxa-Michael reaction cascade of 1,3-dihydro-2-benzofuran-1-ol.
Application In Synthesis of Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem