Month: November 2021

Category: benzofurans. Liu, YY; Zhao, H; Xie, J; Zou, J; Hu, D; Guo, LD; Chen, GD; Yao, XS; Gao, H in [Liu, Yan-Ying; Xie, Jun; Zou, Jian; Hu, Dan; Chen, Guo-Dong; Yao, Xin-Sheng; Gao, Hao] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangdong Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Guangdong, Peoples R China; [Zhao, Huan] Jinan Univ, Coll Tradit Chinese Med, Guangzhou 510632, Guangdong, Peoples R China; [Guo, Liang-Dong] Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China published New phthalide derivatives from the Biscogniauxia sp. and their activities in 2019, Cited 23. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Five new phthalide derivatives, biscogniphthalides A-D (1, 2, 3a/3b, and 4), were isolated from Biscogniauxia sp. (No. 69-8-7-1), along with one related known phthalide (5). Their structures were determined by comprehensive spectroscopic analyses, chemical derivatization, and quantum chemical ECD calculations. In addition, the anti-acetyl cholinesterase, antimicrobial, and anti-a-glucosidase activities of 1-5 were evaluated.

Category: benzofurans. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about MICHAEL ADDITION; CONVENIENT SYNTHESIS; METHYL ETHERS; CHEMISTRY; ACIDS; DIHYDRONAPHTHOQUINONES; CITALOPRAM; INHIBITORS; KETONES; CENTERS, Saw an article supported by the University of Salerno. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Sicignano, M; Schettini, R; Pierri, G; Marino, ML; Izzo, I; De Riccardis, F; Bernardi, L; Della Sala, G. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Recommanded Product: Isobenzofuran-1(3H)-one

A novel asymmetric phase-transfer-catalyzed gamma-alkylation of phthalide 3-carboxylic esters has been developed, giving access to 3,3-disubstituted phthalide derivatives, which present a chiral quaternary gamma-carbon in good to excellent yields and good enantioselectivities (74-88% ee). The enantiomeric purity could be substantially enhanced to 94-95% ee by recrystallization. Both electron-withdrawing and electron-releasing substituents are well tolerated on the phthalide core as well as on the aromatic moiety of the alkylating agent. This methodology, enabling the introduction of an unfunctionalized group at the phthalide gamma-position, fully complements previously reported organocatalytic strategies involving functionalized electrophiles, thus expanding the scope of accessible 3,3-disubstituted products. The high synthetic value of this asymmetric reaction has been proven by the formal synthesis of the naturally occurring alkaloid (+)-(9S,13R)-13-hydroxyisocyclocelabenzine.

Welcome to talk about 87-41-2, If you have any questions, you can contact Sicignano, M; Schettini, R; Pierri, G; Marino, ML; Izzo, I; De Riccardis, F; Bernardi, L; Della Sala, G or send Email.. Recommanded Product: Isobenzofuran-1(3H)-one

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Application In Synthesis of Isobenzofuran-1(3H)-one. Authors Liang, XY; Yu, P; Fu, C; Shen, YC in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Liang, Xiayu; Yu, Peng; Fu, Chen; Shen, Yongcun] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 122 Luoshi Rd, Wuhan 430070, Peoples R China in 2021, Cited 31. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

A new strategy for the facile synthesis of hydroxyalkylamides through the ring-opening reaction of lactone with amine promoted by dibutyltin acetate was developed. A series of hydroxyalkylamide compounds were obtained and the method was successfully applied to the synthesis of pharmaceutically active molecules tyrosinase inhibitor V and HDAC inhibitor VI via a three-step synthetic pathway. The broad substrate scope, mild reaction conditions and practical application proved the effectiveness, compatibility and practicality of this method. (C) 2021 Elsevier Ltd. All rights reserved.

Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Liang, XY; Yu, P; Fu, C; Shen, YC or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recommanded Product: Isobenzofuran-1(3H)-one. In 2020 MOLECULES published article about THIOUREA DERIVATIVES; ANTIFUNGAL ACTIVITY; CRYSTAL; ACID; TRIFLUOROMETHYLATION; ANTIMALARIAL; DISCOVERY; HIV in [Limban, Carmen; Vlad, Ilinca Margareta; Nuta, Diana Camelia] Carol Davila Univ Med & Pharm, Dept Pharmaceut Chem, Bucharest 020956, Romania; [Chifiriuc, Mariana Carmen; Marutescu, Luminita Gabriela] Univ Bucharest, Fac Biol, Dept Microbiol, ICUB, Bucharest 060101, Romania; [Chifiriuc, Mariana Carmen; Marutescu, Luminita Gabriela] Univ Bucharest, Res Inst, ICUB, Bucharest 060101, Romania; [Caproiu, Miron Teodor; Dumitrascu, Florea] Romanian Acad CD Nenitescu, Organ Chem Ctr, Bucharest 060023, Romania; [Ferbinteanu, Marilena] Univ Bucharest, Fac Chem, Inorgan Chem Dept, Bucharest 020462, Romania; [Pintilie, Lucia; Stefaniu, Amalia] Natl Inst Chem Pharmaceut Res & Dev, Bucharest 031299, Romania; [Bleotu, Coralia] Stefan S Nicolau Inst Virol, Mihai Bravu 285, Bucharest 030304, Romania in 2020, Cited 64. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

The increasing threat of antimicrobial resistance to all currently available therapeutic agents has urged the development of novel antimicrobials. In this context, a series of new benzoylthiourea derivatives substituted with one or more fluorine atoms and with the trifluoromethyl group have been tested, synthesized, and characterized by IR, NMR, CHNS and crystal X-ray diffraction. The molecular docking has provided information regarding the binding affinity and the orientation of the new compounds to Escherichia coli DNA gyrase B. The docking score predicted the antimicrobial activity of the studied compounds, especially against E. coli, which was further demonstrated experimentally against planktonic and biofilm embedded bacterial and fungal cells. The compounds bearing one fluorine atom on the phenyl ring have shown the best antibacterial effect, while those with three fluorine atoms exhibited the most intensive antifungal activity. All tested compounds exhibited antibiofilm activity, correlated with the trifluoromethyl substituent, most favorable in para position.

Recommanded Product: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Limban, C; Chifiriuc, MC; Caproiu, MT; Dumitrascu, F; Ferbinteanu, M; Pintilie, L; Stefaniu, A; Vlad, IM; Bleotu, C; Marutescu, LG; Nuta, DC or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Aniline-Type Hypervalent Iodine(III) for Intramolecular Cyclization via C-H Bond Abstraction of Hydrocarbons Containing N- and O-Nucleophiles WOS:000647954700001 published article about REAGENTS; FUNCTIONALIZATION; REACTIVITY; CHEMISTRY in [Nishiguchi, Yuna; Moriyama, Katsuhiko] Chiba Univ, Grad Sch Sci, Dept Chem, Inage Ku, 1-33 Yayoi Cho, Chiba 2638522, Japan; [Nishiguchi, Yuna; Moriyama, Katsuhiko] Chiba Univ, Soft Mol Activat Res Ctr, Inage Ku, 1-33 Yayoi Cho, Chiba 2638522, Japan in 2021, Cited 42. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. HPLC of Formula: C8H6O2

We developed a method for the preparation of (diacetoxyiodo)-2-(N-alkylamido)benzene as an aniline-type hypervalent iodine(III). We also achieved direct cyclizations via C-H bond abstraction, such as the Hofmann-Loffler-Freytag reaction, a direct amination, and a direct lactonization, using the aniline-type hypervalent iodine(III) to obtain corresponding products in high yields.

HPLC of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Nishiguchi, Y; Moriyama, K or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about C-H BONDS; CATALYZED BORYLATION; PHOTOINDUCED BORYLATION; ORGANOBORON CHEMISTRY; N-TOSYLHYDRAZONES; ADDITIVE-FREE; ESTERS; EFFICIENT; CARBON; FUNCTIONALIZATION, Saw an article supported by the Canada Research Chair FoundationCanada Research Chairs; Canada Foundation for InnovationCanada Foundation for InnovationCGIAR; FQRNT Center in Green Chemistry and CatalysisFQRNT; Natural Sciences and Engineering Research Council of CanadaNatural Sciences and Engineering Research Council of Canada (NSERC)CGIAR; McGill University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Li, JB; Wang, HN; Qiu, ZH; Huang, CY; Li, CJ. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Formula: C8H6O2

Direct conversion of aldehydes and ketones into alkylboronic esters via deoxygenative borylation represents an unknown yet highly desirable transformation. Herein, we present a one-step and metal-free method for carbonyl deoxy-borylation under mild conditions. A wide range of aromatic aldehydes and ketones are tolerated and successfully converted into the corresponding benzylboronates. By the same deoxygenation manifold with aliphatic aldehydes and ketones, we also enable a concise synthesis of 1,1,2-tris(boronates), a family of compounds that currently lack efficient synthetic methods. Given its simplicity and versatility, we expect that this novel borylation approach could show great promise in organoboron synthesis and inspire more carbonyl deoxygenative transformations in both academic and industrial settings.

Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Li, JB; Wang, HN; Qiu, ZH; Huang, CY; Li, CJ or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

I found the field of Chemistry; Materials Science very interesting. Saw the article Coal tar- and residual oil-derived porous carbon as metal-free catalyst for nitroarene reduction to aminoarene published in 2019. Safety of Isobenzofuran-1(3H)-one, Reprint Addresses Shen, WZ (corresponding author), Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Shanxi, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Nitroarenes reduction is an important technology in the industrial production of aminoarenes. In this work, we presented an environment-friendly and low-cost green synthesis route for preparation of oxygen and nitrogen co-doped porous carbon (ONPC) via acid oxidation and alkali activation methods using coal tar- and residual oil-based as starting materials, and the prepared ONPC was employed as metal-free carbon catalyst for nitroarenes reduction to aminoarenes in the presence of hydrazine hydrate. This ONPC catalyst showed much higher catalytic activity as compared to those of un-doped porous carbon (PC), activated carbon (AC) and carbon black, which was attributed to its large surface area and developed pore structure as well as O and N co-doping. Additionally, it also exhibited a versatility in various aromatic nitro-compounds reduction to relative aromatic amines. Experimental results by using model catalysts to simulate different carbons with various oxygen-containing groups proved that carbonyl groups were more favorable for nitrobenzene reduction to aniline. Upon co-doping O and N into PC, the two kinds of introduced species synergistically promoted the catalytic activity of PC. Good performance together with low-cost preparation makes oxygen and nitrogen co-doped porous carbon a potential substitution of supported metal catalyst for nitroarenes reduction. (C) 2018 Elsevier Ltd. All rights reserved.

Safety of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Wei, QH; Qin, FF; Ma, QX; Shen, WZ or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Product Details of 87-41-2. I found the field of Chemistry; Environmental Sciences & Ecology very interesting. Saw the article Synthesis of polyoxymethylene dimethyl ethers from dimethoxymethane and trioxymethylene over graphene oxide: Probing the active species and relating the catalyst structure to performance published in 2019, Reprint Addresses Wu, ZW; Qin, ZF; Wang, JG (corresponding author), Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, POB 165, Taiyuan 030001, Shanxi, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

Polyoxymethylene dimethyl ethers (PODE, with the formula of CH3O-(CH2O)(n)-CH3), as a promising environmentally benign diesel fuel or additive with an enormous potential in the reduction of soot and NIC, emissions, can be efficiently synthesized from methanol derivatives such as dimethoxymethane (DMM) and trioxymethylene (TOM), which requests a proper catalyst of high performance. In this work, the catalytic performance of graphene oxide (GO) in the synthesis of PODEn as well as its relation to the catalyst structure was thoroughly investigated. The results indicate that GO is an excellent catalyst in the synthesis of PODEn from DMM and TOM; a TOM conversion of 94.6% and selectivity of 86.0% to PODE2-8 are achieved under mild reaction conditions, which is superior to the majority of the state-of-the-art catalysts. Meanwhile, the active species and characteristic layer structure of GO sheets catalytically responsible for PODEn formation were discriminated through selectively removing certain surface functional groups, thermally annealing at different temperatures, and carefully comparing with a series of model compounds. The results illustrate that the superior catalytic performance of GO in the PODEn synthesis should be ascribed to a synergy between the surface sulfonyl, hydroxyl and carboxyl groups present on the GO surface and the unique layered structure of GO sheets, wherein the surface sulfonyl groups act as the main active sites. The insights shown in this work are beneficial to a deep understanding on the catalytic principle of GO and development of efficient catalyst for the synthesis of PODEn.

Product Details of 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Wang, RY; Wu, ZW; Li, ZK; Qin, ZF; Chen, CM; Zheng, ZF; Wang, GF; Fan, WB; Wang, JG or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Application of polar solvent effects in absorption spectra for determination of lowest electron-excited states of phthalide WOS:000456799900022 published article about AQUEOUS-SOLUTION; FLUORESCENCE; MOLECULES; DYNAMICS; URACIL in [Tseplin, Evgeniy E.; Tseplina, Svetlana N.] Russian Acad Sci, Ufa Fed Res Ctr, Inst Mol & Crystal Phys, Prospekt Oktyabrya 151, Ufa 450075, Russia in 2019, Cited 37. SDS of cas: 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

The optical absorption spectra of phthalide in polar (methanol) and nonpolar (n-hexane) solvents are recorded. The electronic phthalide spectrum was calculated by TDDFT B3LYP/6-311 + G(d, p) using the polarisable continuum model. Based on an analysis of calculation data and the displacement of absorption bands in a polar solvent, it was established that the absorption bands of phthalide at energies of 3.51 and 3.96 eV correspond to singlet-triplet transitions to the T-1 and T-2 states, respectively.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Tseplin, EE; Tseplina, SN or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about MEDIATED 2+2+1 CYCLOADDITIONS; IRON-CATALYZED HYDROGENATION; OPPENAUER-TYPE OXIDATION; METAL-DIENE COMPLEXES; REGIOSELECTIVE DEHYDROGENATION; AEROBIC OXIDATION; ORGANIC-SYNTHESIS; CARBON-MONOXIDE; LACTONIZATION; ALCOHOLS, Saw an article supported by the UR American Chemical Society Petroleum Research Fund grant [52162-UR1]; Cross Disciplinary Science Institute at Gettysburg College (X-SIG); Gettysburg College. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Tang, YD; Meador, RIL; Malinchak, CT; Harrison, EE; McCaskey, KA; Hempel, MC; Funk, TW. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Recommanded Product: 87-41-2

Air-stable iron carbonyl compounds bearing cyclo-pentadienone ligands with varying substitution were explored ,as catalysts in dehydrogenative diol lactonization reactions using acetone as both the solvent and hydrogen acceptor. Two catalysts with trimethylsilyl groups in the 2- and 5-positions, [2,S-(SiMe3)(2)-3,4-(CH2)(4)(eta(4)-C4C=O))Fe(CO)(3) (1) and [2,5-(SiMe3)(2)-3,4(CH2)(3)(eta(4)-C4C=O)]Fe(CO)(3) (2), were found to be the most active, with 2 being the most selective in the lactonization of diols containing both primary and secondary alcohols. Lactones containing five-, six-, and seven-membered rings .were successfully synthesized, and no over-oxidations to carboxylic acids were detected. The lactonization of unsymmetrical diols containing two primary alcohols occurred with catalyst 1, but selectivity was low based on alcohol electronics and modest based on alcohol sterics. Evidence for a transfer dehydrogenation mechanism was found, and insight into the origin of selectivity in the lactonization of 1 degrees/2 degrees diols was obtained. Additionally, spectroscopic evidence for a trimethylamine-ligated iron species formed in solution during the reaction was discovered.

Recommanded Product: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Tang, YD; Meador, RIL; Malinchak, CT; Harrison, EE; McCaskey, KA; Hempel, MC; Funk, TW or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem