Day: November 4, 2021

An article An Entry to Enantioenriched 3,3-Disubstituted Phthalides through Asymmetric Phase-Transfer-Catalyzed gamma-Alkylation Marina WOS:000538764000061 published article about MICHAEL ADDITION; CONVENIENT SYNTHESIS; METHYL ETHERS; CHEMISTRY; ACIDS; DIHYDRONAPHTHOQUINONES; CITALOPRAM; INHIBITORS; KETONES; CENTERS in [Sicignano, Marina; Schettini, Rosaria; Pierri, Giovanni; Marino, Maria Leda; Izzo, Irene; De Riccardis, Francesco; Della Sala, Giorgio] Univ Salerno, Dipartimento Chim & Biol Zambelli, I-84084 Fisciano, SA, Italy; [Bernardi, Luca] Alma Mater Studiorum Univ Bologna, Dept Ind Chem Toso Montanari, I-40136 Bologna, Italy; [Bernardi, Luca] Alma Mater Studiorum Univ Bologna, INSTM RU Bologna, I-40136 Bologna, Italy in 2020, Cited 63. COA of Formula: C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

A novel asymmetric phase-transfer-catalyzed gamma-alkylation of phthalide 3-carboxylic esters has been developed, giving access to 3,3-disubstituted phthalide derivatives, which present a chiral quaternary gamma-carbon in good to excellent yields and good enantioselectivities (74-88% ee). The enantiomeric purity could be substantially enhanced to 94-95% ee by recrystallization. Both electron-withdrawing and electron-releasing substituents are well tolerated on the phthalide core as well as on the aromatic moiety of the alkylating agent. This methodology, enabling the introduction of an unfunctionalized group at the phthalide gamma-position, fully complements previously reported organocatalytic strategies involving functionalized electrophiles, thus expanding the scope of accessible 3,3-disubstituted products. The high synthetic value of this asymmetric reaction has been proven by the formal synthesis of the naturally occurring alkaloid (+)-(9S,13R)-13-hydroxyisocyclocelabenzine.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Name: Isobenzofuran-1(3H)-one. I found the field of Chemistry very interesting. Saw the article Redox deracemization of alpha-substituted 1,3-dihydroisobenzofurans published in 2021, Reprint Addresses Liu, L (corresponding author), Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Jinan 250012, Peoples R China.; Liu, QY (corresponding author), Shandong Univ Sci & Technol, Coll Chem & Biol Engn, State Key Lab Min Disaster Prevent & Control Cofo, Qingdao 266590, Peoples R China.; Liu, QY (corresponding author), Shandong Univ Sci & Technol, Minist Sci & Technol, Qingdao 266590, Peoples R China.; Sun, X (corresponding author), Shandong Univ, Cheeloo Coll Med, Sch Basic Med Sci, Dept Pharmacol, Jinan 250012, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

Chiral alpha-substituted 1,3-dihydroisobenzofurans are key scaffolds in a number of bioactive natural products and synthetic pharmaceuticals. However, catalytic asymmetric approaches have been rarely developed. Here, a redox deracemization technology is adopted to address the catalytic asymmetric synthesis. A broad range of alpha-aryl substituted 1,3-dihydroisobenzofurans are effectively deracemized in high efficiency with excellent ee. alpha-Alkynyl substituted ethers were also compatible with the deracemization technology. (c) 2021 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Name: Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Ovchinnikov, MY; Antipin, VA; Khursan, SL in [Ovchinnikov, Mikhail Yu; Antipin, Vyacheslav A.; Khursan, Sergey L.] Ufa Inst Chem UFRC RAS, 71 Prospect Oktyabrya, Ufa 450054, Russia published Thermostimulated luminescence of poly(diphenylenephthalide) films. Kinetics and mechanistic steps of irradiative processes in 2020, Cited 59. Application In Synthesis of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Kinetics of thermostimulated luminescence (TSL) of poly(diphenylenephthalide) (PDPh) films has been studied using mathematical modelling and DFT approximation. TSL of PDPh-film was considered to be arising from irradiative deactivation of diphenylene (DP) fragment of polymer chain in excited state formed upon recombination of the spatial separated ion-radical pairs generated by photoexcitation. Two parallel monomolecular transformations leading to excited DP have been revealed: the first path is characterized by the activation parameters of the kinetic rate constant k1 which equal to Al ti 105 sec 1 and Eat ti 70 kJ mol(-1). This path may be interpreted in terms of mechanical relaxation theory by segmental polymer mobility as electron transfer (ET) from phthalide (Ph) anion-to DP cation-radical. The second channel is supposed to be consist of two consecutive ET from triarylmethyl anion-radical to phthalide neutral (A2 ti 1 sec 1, Ea2 ti 20 kJ mol(-1)), and then to DP cation-radical (A3 N 104 sec 1, E,3 N 40 kJ mol(-1)) of the polymer chain indicating y- and fl-relaxation, respectively. The revealed mechanistic steps and electron retention efficiency estimated in B97-2/6-311 + G(d,p) approximation for the most probable anion-radicals may point out the key role of domino quantum tunneling in transfer and recombination of charges in PDPh films.

Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Ovchinnikov, MY; Antipin, VA; Khursan, SL or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters WOS:000460683700012 published article about ACCEPTORLESS DEHYDROGENATION; ALIPHATIC-ALCOHOLS; COMPLEXES; OXIDATION; ESTERIFICATION in [Jiang, Xiaolin; Zhao, Dongmei] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China; [Jiang, Xiaolin; Zhang, Jiahui; Li, Yuehui] Chinese Acad Sci, State Key Lab Oxo Synth & Select Oxidat, Lanzhou Inst Chem Phys, Suzhou Res Inst LICP, Lanzhou 730000, Peoples R China; [Zhang, Jiahui] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China in 2019, Cited 25. Quality Control of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

The presence of different aldehydes is found to have a significant influence on the catalytic performance when using PN(H)P type ligands for dehydrogenation of alcohols. Accordingly, hybrid multi-dentate ligands were discovered based on an oxygen-transfer alkylation of PNP ligands by aldehydes. The relevant Ru-PNN(PO) system provided the desired unsymmetrical esters in good yields via acceptorless dehydrogenation of alcohols. Hydrogen bonding interactions between the phosphine oxide moieties and alcohol substrates likely assisted the observed high chemoselectivity.

Quality Control of Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about PALLADIUM-CATALYZED CARBONYLATION; METAL-FREE CONSTRUCTION; ARYL HALIDES; N-FORMYLSACCHARIN; EX-SITU; CO; HYDROESTERIFICATION; AMINOCARBONYLATION; ALKYNES; SEQUENCE, Saw an article supported by the Zhejiang Provincial Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province [LY19B020004, LQ15B060005]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21606080]; Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2018BB029]; Summit Program of Jiaxing University for Leading Talents. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Chen, DP; Yao, JZ; Chen, LL; Hu, LF; Li, XF; Zhou, HW. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. SDS of cas: 87-41-2

A highly efficient palladium-catalyzed TBD-formate system for carbonylation/hydrogenation was reported. Based on the obvious solvent effect and reasonable mechanism study, we achieved tunable carbonylation or hydrogenation. With the advantages of simple operation, mild conditions and storable reagents, this protocol should be of interest not only for synthetic scientists but also helpful for laboratory operators.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Chen, DP; Yao, JZ; Chen, LL; Hu, LF; Li, XF; Zhou, HW or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

HPLC of Formula: C8H6O2. Collin, DE; Folgueiras-Amador, AA; Pletcher, D; Light, ME; Linclau, B; Brown, RCD in [Collin, Diego E.; Folgueiras-Amador, Ana A.; Pletcher, Derek; Light, Mark E.; Linclau, Bruno; Brown, Richard C. D.] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England published Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions in 2020, Cited 64. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

The highly strained cubane system is of great interest as a scaffold and rigid linker in both pharmaceutical and materials chemistry. The first electrochemical functionalisation of cubane by oxidative decarboxylative ether formation (Hofer-Moest reaction) was demonstrated. The mild conditions are compatible with the presence of other oxidisable functional groups, and the use of flow electrochemical conditions allows straightforward upscaling.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Cu(I)-Based Metal-Organic Frameworks as Efficient and Recyclable Heterogeneous Catalysts for Aqueous-Medium C-H Oxidation WOS:000458348000054 published article about AEROBIC OXIDATION; COORDINATION POLYMERS; BONDS ACTIVATION; HIGHLY EFFICIENT; FACILE SYNTHESIS; KETONES; WATER; ARYLALKANES; CONVERSION; SORPTION in [Gao, Kuan; Yang, Yisen; Li, Hong; Wu, Jie; Hou, Hongwei] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China; [Huang, Chao] Zhongyuan Univ Technol, Ctr Adv Mat Res, Zhengzhou 450001, Henan, Peoples R China in 2019, Cited 48. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Safety of Isobenzofuran-1(3H)-one

The enantioselective transformation of ubiquitous C-H bonds into valuable C=O bonds offers an efficient synthetic approach to construct carbonyl functionalized molecules. However, the grand obstacles in the reaction are the selectivity issues and side reactions under the harsh reaction conditions. In order to overcome the limits, two Cu(I)-based MOFs {(NEt4)(0.5)[Cu-3 (TTPB)(0.75) (CN)(0.5)(H2O)]center dot H2O}(n) (1) and {[Cu-2 (TTPB)(0.5)]center dot DMF center dot 2H(2)O}(n) (2) were synthesized (H-4 TTPB = 5,5′ – (4′,5′ -bis (4- (1H-tetrazol-5-yl)phenyl)- [1,1′ :2′,1 ”-terphenyl]-4,4 ”-diyl) bis(1H-tetrazole)) under hydrothermal conditions with (triethylamine (TEA) and ethyldiisopropylamine (DIPEA) as structure-directing agents, respectively. Of these, 1 shows an anionic three-dimensional (3D) framework composed of two kinds of cagelike micropores with 7 X 17 angstrom and 10 x 17 angstrom, respectively. In comparison, 2 exhibits a 3D framework with open channels (14 x 8 angstrom). The stability studies showed that the crystallinity of 1 and 2 could remain in a series of organic solvents (ethanol, N,N-dimethylformamide, chloroform, dioxane, toluene) and acid and alkali aqueous solutions (pH = 1-13) at room temperature for 48 h. 1 and 2 with coordinatively unsaturated Cu(I) sites were applied as heterogeneous catalysts for the oxidation of arylacycloalkanes in aqueous medium and exhibited excellent catalytic activities, selectivities, and recyclabilities. Moreover, free-radical reaction mechanism and reversible valence-tautomeric conversions of central copper were confirmed during the process by control experiment.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Hassan, AY; Mohamed, MA; Abdel-Aziem, A; Hussain, AO in [Hassan, A. Y.; Abdel-Aziem, A.; Hussain, A. O.] Al Azhar Univ, Chem Dept, Fac Sci, Girls Branch, POB 11754,Yousef Abbas Str, Cairo, Egypt; [Mohamed, M. A.] Al Azhar Univ, Girls Branch, Fac Sci, Biochem Div,Chem Dept, Cairo, Egypt published Synthesis and Anticancer Activity of Some Fused Heterocyclic Compounds Containing Pyrazole Ring in 2020, Cited 25. Product Details of 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

5-Amino-1-phenyl-1H-pyrazole-4-carbohydraizde(1) was used as a key to synthesize new imidazopyrazol-5(1H)-one 5, pyrazolopyrimidines 7 and 9. Furthermore, imidazopyrazoles 13, 15, pyrazolopyridine 16 and pyrazolopyrazolopyridopyrimidine 17 were prepared from pyrazoles 10 and 11. The structure of the new compounds was confirmed by spectral data as well as elemental analysis. Some compounds were selected by the national cancer institute NCI (USA) for anticancer activity against different human cancer cell lines. The results indicated that compound 12 exhibited strong anticancer activity toward Renal Cancer UO-31(GI, 42.81%), while compound 3 was strong active against Breast Cancer MCF7 (GI, 49.88%) and moderate against T-47D (GI, 38.15%) cell lines. However, compound 17 showed strong activity against Leukemia CCRF-CEM (GI, 41.37%) and SR (GI, 44.95%), whereas, compound 9 showed weak activity toward all tested cancer cell lines.

Product Details of 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Hassan, AY; Mohamed, MA; Abdel-Aziem, A; Hussain, AO or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2020 WATER RES published article about MUSSEL MYTILUS-EDULIS; SEA-URCHIN; BISPHENOL-A; TOXICITY; METALS; EMBRYOS; WATER; ZINC; MICROPLASTICS; ENVIRONMENT in [Capolupo, Marco; Jayasena, Kongalage Don Ranil; Fabbri, Elena] Univ Bologna, Dept Biol Geol & Environm Sci, Via St Alberto 163, I-48123 Ravenna, Italy; [Sorensen, Lisbet; Booth, Andy M.] SINTEF Ocean Environm & New Resources, Postboks 4762, N-7465 Trondheim, Norway in 2020, Cited 66. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. HPLC of Formula: C8H6O2

Synthetic polymer-based materials are ubiquitous in aquatic environments, where weathering processes lead to their progressive fragmentation and the leaching of additive chemicals. The current study assessed the chemical content of freshwater and marine leachates produced from car tire rubber (CTR), polypropylene (PP), polyethylene terephthalate (PET), polystyrene (PS) and polyvinyl chloride (PVC) microplastics, and their adverse effects on the microalgae Raphidocelis subcapitata (freshwater) and Skeletonema costatum (marine) and the Mediterranean mussel Mytilus galloprovincialis. A combination of non-target and target chemical analysis revealed a number of organic and metal compounds in the leachates, including representing plasticizers, antioxidants, antimicrobials, lubricants, and vulcanizers. CTR and PVC materials and their corresponding leachates had the highest content of tentatively identified organic additives, while PET had the lowest. The metal content varied both between polymer leachates and between freshwater and seawater. Notable additives identified in high concentrations were benzothiazole (CTR), phthalide (PVC), acetophenone (PP), cobalt (CTR, PET), zinc (CTR, PVC), lead (PP) and antimony (PET). All leachates, except PET, inhibited algal growth with EC50 values ranging from 0.5% (CTR) and 64% (PP) of the total leachate concentration. Leachates also affected mussel endpoints, including the lysosomal membrane stability and early stages endpoints as gamete fertilization, embryonic development and larvae motility and survival. Embryonic development was the most sensitive parameter in mussels, with EC50 values ranging from 0.8% (CTR) to 65% (PET) of the total leachate. The lowest impacts were induced on D-shell larvae survival, reflecting their ability to down-regulate motility and filtration in the presence of chemical stressors. This study provides evidence of the relationship between chemical composition and toxicity of plastic/rubber leachates. Consistent with increasing contamination by organic and inorganic additives, the leachates ranged from slightly to highly toxic to mussels and algae, highlighting the need for a better understanding of the overall impact of plastic-associated chemicals on aquatic ecosystems. (C) 2019 The Authors. Published by Elsevier Ltd.

HPLC of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Capolupo, M; Sorensen, L; Jayasena, KD; Booth, AM; Fabbri, E or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Manganese catalyzed selective hydrogenation of cyclic imides to diols and amines WOS:000537870500006 published article about HOMOGENEOUS CATALYSIS; ALCOHOLS; EFFICIENT; AMIDES; KETONES; ESTERS; DESYMMETRIZATION; DEHYDROGENATION; MONOREDUCTION; REDUCTION in [Das, Uttam Kumar; Janes, Trevor; Kumar, Amit; Milstein, David] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel; [Kumar, Amit] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland in 2020, Cited 43. Computed Properties of C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Herein we report the selective hydrogenation of cyclic imides to diols and amines, homogeneously catalyzed for the first time by a complex of an earth-abundant metal, a manganese pincer complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments.

Computed Properties of C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem