Heterocyclic Building Block-benzofuran

Anti-inflammatory activity of caffeic acid derivatives isolated from the roots of Salvia miltiorrhiza Bunge was written by Choi, Hyun Gyu;Tran, Phuong Thao;Lee, Jeong-Hyung;Min, Byung Sun;Kim, Jeong Ah. And the article was included in Archives of Pharmacal Research in 2018.Name: (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2S,3S)-2-(3,4-dihydroxyphenyl)-4-((E)-3-(((R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)oxy)-3-oxoprop-1-en-1-yl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylate This article mentions the following:

Ten caffeic acid derivatives (1-10) were isolated from the roots of S. miltiorrhiza by using various chromatog. methods and their chem. structures were spectroscopically elucidated. The absolute configurations of chiral centers were determined by comparison with reported coupling constants, optical rotation values, and CD techniques. Anti-inflammatory activities were evaluated using NO, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) inhibition assays, and by determining the expression of heme oxygenase-1 (HO-1). Two new caffeic acid derivatives, 8-epiblechnic acid 9-Me ester (4) and 8-epiblechnic acid 9′-Me ester (5), and 8 known derivatives, caffeic acid Me ester (1), shimobashiric acid B (2), rosmarinic acid Me ester (3), salvianolic acid C (6), Me salvianolate C (7), lithospermic acid monomethyl ester (8), lithospermic acid di-Me ester (9), and di-Me lithospermate B (10), were isolated from the EtOAc fraction of S. miltiorrhiza. All caffeic acid derivatives were evaluated for their inhibitory effect on NO production Compounds 2 and 3 inhibited NO production with IC₅₀ values of 1.4 and 0.6 μM, resp. These compounds also strongly inhibited the production of iNOS and COX-2. In addition, compound 3 induced the expression HO-1 in a concentration-dependent manner at 0.1, 0.3, and 1.0 μM. In the experiment, the researchers used many compounds, for example, (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2S,3S)-2-(3,4-dihydroxyphenyl)-4-((E)-3-(((R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)oxy)-3-oxoprop-1-en-1-yl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylate (cas: 875313-64-7Name: (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2S,3S)-2-(3,4-dihydroxyphenyl)-4-((E)-3-(((R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)oxy)-3-oxoprop-1-en-1-yl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylate).

(R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2S,3S)-2-(3,4-dihydroxyphenyl)-4-((E)-3-(((R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)oxy)-3-oxoprop-1-en-1-yl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylate (cas: 875313-64-7) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Name: (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2S,3S)-2-(3,4-dihydroxyphenyl)-4-((E)-3-(((R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)oxy)-3-oxoprop-1-en-1-yl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylate

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Allergen-specific T-cell response in patients with phenytoin hypersensitivity; simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester (CFSE) dilution assay was written by Tsuge, Ikuya;Okumura, Akihisa;Kondo, Yasuto;Itomi, Seiko;Kakami, Michiko;Kawamura, Makiko;Nakajima, Yoichi;Komatsubara, Ryo;Urisu, Atsuo. And the article was included in Allergology International in 2007.Application In Synthesis of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate This article mentions the following:

Background: Phenytoin can induce diversified adverse reactions including generalized eruptions and the hypersensitivity syndrome. Delayed-type allergic mechanisms have been postulated to underlie these reactions. The tests most widely used to detect T-cell sensitization to drugs are the patch test and the lymphocyte transformation test (LTT), but their sensitivity is not sufficient. Simultaneous assessment of both the frequencies and the cytokine-producing phenotypes of allergen-specific T cells has become possible with the recently introduced carboxyfluorescein succinimidyl ester (CFSE) assay. Methods: Seven patients who presented with phenytoin-induced maculopapular exanthema with and without fever were included in this study. Peripheral blood mononuclear cells (PBMCs) were labeled with CFSE and cultured with phenytoin for seven days. The cells were stained with anti-CD4 and cytokine-specific monoclonal antibodies (MoAbs), and analyzed with FACSCalibur. Results: The phenytoin-specific proliferation of CD4⁺ cells in patients was significantly higher than in the four controls exposed to phenytoin, and in seven healthy children with no previous phenytoin intake. A significant difference in the percentages of CD4⁺ IFN-γ⁺ cells between patients and the seven healthy children was observed The sensitivity and specificity of proliferation were 100% and 90.9%, and those of IFN-γ secretion were 71.4% and 100%, resp. Conclusions: Phenytoin-specific proliferation may be detected with greater sensitivity by the CFSE dilution assay than the conventional LTT. The assay revealed that both CD4⁺ and CD4^– T cells proliferated and produced IFN-γ and TNF-α after stimulation with phenytoin. The CFSE dilution assay might be useful for the diagnosis and understanding of drug hypersensitivity. In the experiment, the researchers used many compounds, for example, 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7Application In Synthesis of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate).

2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Application In Synthesis of 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Transpositive Tandem Annulation of Phthalides with Allene Carboxylates: Regioselective Synthesis of Arylnaphthalene Lignans was written by Mal, Dipakranjan;Jana, Supriti. And the article was included in Journal of Organic Chemistry in 2016.Safety of 5-Methoxyisobenzofuran-1(3H)-one This article mentions the following:

Allene carboxylates, scarcely used as Michael acceptors, serve as acceptors in the annulation with phthalides in the presence of LDA and provide a one-pot synthesis of naphtho[c]furanones in very good yields. This tandem annulation is proposed to proceed via transposition of the hydroxy group resulting from the initial annulation. In the experiment, the researchers used many compounds, for example, 5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2Safety of 5-Methoxyisobenzofuran-1(3H)-one).

5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Safety of 5-Methoxyisobenzofuran-1(3H)-one

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Molecular nanoinformatics approach assessing the biocompatibility of biogenic silver nanoparticles with channelized intrinsic steatosis and apoptosis was written by Panda, Pritam Kumar;Kumari, Puja;Patel, Paritosh;Samal, Shailesh Kumar;Mishra, Suman;Tambuwala, Murtaza M.;Dutt, Ateet;Hilscherova, Klara;Mishra, Yogendra Kumar;Varma, Rajender S.;Suar, Mrutyunjay;Ahuja, Rajeev;Verma, Suresh K.. And the article was included in Green Chemistry in 2022.Related Products of 496-16-2 This article mentions the following:

The developmental rapidity of nanotechnol. poses higher risks of exposure to humans and the environment through manufactured nanomaterials. The multitude of biol. interfaces, such as DNA, proteins, membranes, and cell organelles, which come in contact with nanoparticles, is influenced by colloidal and dynamic forces. Consequently, the ensued nano-bio interface depends on dynamic forces, encompasses many cellular absorption mechanisms along with various biocatalytic activities, and biocompatibility that needs to be investigated in detail. Addressing the issue, the study offers a novel green synthesis strategy for antibacterial AgNPs with higher biocompatibility and elucidates the mechanistic in vivo biocompatibility of silver nanoparticles (AgNPs) at the cellular and mol. levels. The anal. ascertained the biosynthesis of G-AgNPs with the size of 25 ± 10 nm and zeta potential of -29.2 ± 3.0 mV exhibiting LC50 of 47.2 μg mL-1 in embryonic zebrafish. It revealed the mechanism as a consequence of abnormal physiol. metabolism in oxidative stress and neutral lipid metabolism due to dose-dependent interaction with proteins such as he1a, sod1, PEX protein family, and tp53 involving amino acids such as arginine, glutamine and leucine leading to improper apoptosis. The research gave a detailed insight into the role of diverse AgNPs-protein interactions with a unique combinatorial approach from first-principles d. functional theory and in silico analyses, thus paving a new pathway to comprehending their intrinsic properties and usage. In the experiment, the researchers used many compounds, for example, 2,3-Dihydrobenzo[b]furan (cas: 496-16-2Related Products of 496-16-2).

2,3-Dihydrobenzo[b]furan (cas: 496-16-2) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Related Products of 496-16-2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Novel one pot synthesis of 3-acetyl-5-hydroxy-2-methylbenzofuran and 3-acetyl-5-hydroxy-2-methylnaphthofuran and synthesis of their derivatives was written by Gadaginamath, Guru S.;Kavali, Rajesh R.;Pujar, Shashikanth R.. And the article was included in Synthetic Communications in 2003.Product Details of 28241-99-8 This article mentions the following:

Benzofurans and naphthofurans have so far been obtained, by using either catalyst or as side products. 3-Acetyl-5-hydroxy-2-methylbenzofuran (I; R = H) and 3-acetyl-5-hydroxy-2-methylnaphthofuran (II; R = H) were formed in quant. yield by the Nenitzescu reaction. Further, I and II (R = H) were converted to their corresponding 5-methoxy/5-methoxycarbonylmethoxy derivatives I and II (R = Me, CH₂CO₂Me). In the experiment, the researchers used many compounds, for example, 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8Product Details of 28241-99-8).

1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Product Details of 28241-99-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Important lack of difference in tacrolimus and mycophenolic acid pharmacokinetics between Aboriginal and Caucasian kidney transplant recipients was written by Barraclough, Katherine A.;Metz, David;Staatz, Christine E.;Gorham, Gillian;Carroll, Robert;Majoni, Sandawana William;Cherian, Sajiv;Swaminathan, Ramyasuda;Holford, Nick. And the article was included in Nephrology in 2022.Category: benzofurans This article mentions the following:

To examine whether differences in tacrolimus and mycophenolic acid (MPA) pharmacokinetics contribute to the poorer kidney transplant outcomes experienced by Aboriginal Australians. Concentration-time profiles for tacrolimus and MPA were prospectively collected from 43 kidney transplant recipients: 27 Aboriginal and 16 Caucasian. Apparent clearance (CL/F) and distribution volume (V/F) for each individual were derived from concentration-time profiles combined with population pharmacokinetic priors, with subsequent assessment for between-group difference in pharmacokinetics. In addition, population pharmacokinetic models were developed using the prospective dataset supplemented by previously developed structural models for tacrolimus and MPA. The change in NONMEM objective function was used to assess improvement in goodness of model fit. No differences were found between Aboriginal and Caucasian groups or empirical Bayes estimates, for CL/F or V/F of MPA or tacrolimus. However, a higher prevalence of CYP3A5 expressers (26% compared with 0%) and wider between-subject variability in tacrolimus CL/F (SD = 5.00 compared with 3.25 L/h/70 kg) were observed in the Aboriginal group, though these differences failed to reach statistical significance (p = .07 and p = .08). There were no differences in typical tacrolimus or MPA pharmacokinetics between Aboriginal and Caucasian kidney transplant recipients. This means that Bayesian dosing tools developed to optimize tacrolimus and MPA dosing in Caucasian recipients may be applied to Aboriginal recipients. In turn, this may improve drug exposure and thereby transplant outcomes in this group. Aboriginal recipients appeared to have greater between-subject variability in tacrolimus CL/F and a higher prevalence of CYP3A5 expressers, attributes that have been linked with inferior outcomes. In the experiment, the researchers used many compounds, for example, (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1Category: benzofurans).

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid (cas: 24280-93-1) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Category: benzofurans

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Shape-Encoded Chitosan-Polyacrylamide Hybrid Hydrogel Microparticles with Controlled Macroporous Structures via Replica Molding for Programmable Biomacromolecular Conjugation was written by Kang, Eunae;Jung, Sukwon;Abel, John H.;Pine, Allison;Yi, Hyunmin. And the article was included in Langmuir in 2016.COA of Formula: C25H15NO9 This article mentions the following:

Polymeric hydrogel microparticle-based suspension arrays with shape-based encoding offer powerful alternatives to planar and bead-based arrays toward high throughput biosensing and medical diagnostics. We report a simple and robust micromolding technique for polyacrylamide- (PAAm-) based biopolymeric-synthetic hybrid microparticles with controlled 2D shapes containing a potent aminopolysaccharide chitosan as an efficient conjugation handle uniformly incorporated in PAAm matrix. A postfabrication conjugation approach utilizing amine-reactive chemistries on the chitosan shows stable incorporation and retained chem. reactivity of chitosan, readily tunable macroporous structures via simple addition of low content long-chain PEG porogens for improved conjugation capacity and kinetics, and one-pot biomacromol. assembly via bioorthogonal click reactions with minimal nonspecific binding. We believe that the integrated fabrication-conjugation approach reported here could offer promising routes to programmable manufacture of hydrogel microparticle-based biomacromol. conjugation and biofunctionalization platforms for a large range of applications. In the experiment, the researchers used many compounds, for example, 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7COA of Formula: C25H15NO9).

2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.COA of Formula: C25H15NO9

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Prucalopride in intestinal pseudo obstruction, paediatric experience and systematic review. was written by Mutalib, M;Kammermeier, J;Vora, R;Borrelli, O. And the article was included in Acta gastro-enterologica Belgica in 2021.Recommanded Product: 4-Amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide This article mentions the following:

BACKGROUND: Intestinal pseudo obstruction both acute and chronic is an uncommon severe motility disorder that affect both children and adults, can lead to significant morbidity burden and have no standard management strategy. Prucalopride a highly selective serotonin receptor agonist is an effective laxative with reported extra colon action. We aim to report our experience in children with acute and chronic intestinal pseudo obstruction who responded to prucalopride and systemically review the use of prucalopride in intestinal pseudo obstruction. METHODS: A report of clinical experience and systemic review of the relevant medical databases to identify the outcome of usage of prucalopride in patients with acute and chronic intestinal pseudo obstruction. Studies meeting the selection criteria were reviewed including abstract only and case reports. RESULTS: All reported cases showed clinical response to prucalopride. There were three full text, two abstracts only and three case reports all reporting clinical improvement with prucalopride. CONCLUSION: Prucalopride appears to show promising results in children and adults with acute and chronic intestinal pseudo obstruction. In the experiment, the researchers used many compounds, for example, 4-Amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide (cas: 179474-81-8Recommanded Product: 4-Amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide).

4-Amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide (cas: 179474-81-8) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Recommanded Product: 4-Amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Establishment of a UPLC-MS/MS Method for studying the effect of salt-processing on tissue distribution of twelve major bioactive components of qing’e pills in rats was written by Hou, Jingxia;Lin, Shangyang;Lu, Jinlan;Wu, Yu;Wu, Li;Chen, Zhipeng;Li, Weidong. And the article was included in Journal of Analytical Methods in Chemistry in 2020.Application of 905954-17-8 This article mentions the following:

Qing’e pills is clin. used for treating osteoporosis in postmenopausal women in China. Eucommiae Cortex and Psoraleae Fructus are the main herbs of Qing’e pills and are both required to be salt-processed. In order to study the influence of salt-processing on the tissue distribution of Qing’e pills, a UPLC-MS/MS method was established for studying the tissue distribution of 12 main bioactive ingredients of Qing’e pills in rats. The linear relationships of the 12 compounds in each tissue were good. The method was fully validated for its selectivity, accuracy, precision, stability, matrix effect, and extraction recovery. Then, the validated method was successfully applied for simultaneous determination of the 12 chem. components in Qing’e pills in tissues for the first time. Areas under the curve (AUC) results showed that, except for pinoresinol diglucoside, psoralen, and isopsoralen, the distribution of the other components was increased in the kidney, uterus, ovary, and testes. Relative targeting efficiency (RTE) results showed that all 12 chem. components targeted the kidney and sexual organs. The results indicated that the Eucommiae Cortex and Psoraleae Fructus after salt-processing could significantly increase the distribution of components to the kidney and generative organs. In the experiment, the researchers used many compounds, for example, (Z)-3-(6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzofuran-5-yl)acrylic acid (cas: 905954-17-8Application of 905954-17-8).

(Z)-3-(6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzofuran-5-yl)acrylic acid (cas: 905954-17-8) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Application of 905954-17-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Simultaneous characterization of two types of major active components in Kushen by high performance liquid chromatography coupled to multi-stage mass spectrometry was written by Zhao, Qinqin;Zhang, Yufeng;Fan, Xiaohui. And the article was included in Zhongguo Zhongyao Zazhi in 2011.Reference of 6807-83-6 This article mentions the following:

In this study, a high performance liquid chromatog. coupled with multi-stage mass spectrometry method (HPLC-MS) was developed for simultaneous characterization of alkaloids and flavonoids, the main active components, in Kushen with diverse phys. and chem. properties. Forty-two major constituents, including sixteen Kushen alkaloids and twenty-six Kushen flavonoids were tentatively identified. Addnl., useful and characteristic fragmentation pathways of two types of Kushen alkaloids, namely cytisine-type and sparteine-type, in pos. ions mode were proposed and summarized, which would lay a foundation for the rapid identification of the active ingredients in traditional Chinese medicine Kushen. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6Reference of 6807-83-6).

(2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4′,5′:5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 6807-83-6) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Reference of 6807-83-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem