Ramart, Pauline’s team published research in Compt. rend. in 182 | CAS: 596-01-0

Compt. rend. published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Synthetic Route of 596-01-0.

Ramart, Pauline published the artcileMolecular transpositions in the α,α,α-alkyldiarylethanol series, Synthetic Route of 596-01-0, the publication is Compt. rend. (1926), 1342-4, database is CAplus.

It has already been shown (cf. C. A. 19, 645) that by dehydration of primary alkyldiaryl alcs., transposition of the aryl radical occurs when the hydrocarbon is formed. In a further study of this dehydration and transposition the following alcs. were prepared, the 1st being unknown heretofore. 2,2,3-Triphenylpropanol, Ph2(PhCH2)CCH2OH, from benzyl diphenylbenzylacetate and Na in absolute EtOH, m. 80°, b16 240°; phenylurethan, m. 169°; Bz derivative, m. 95°. (PhCH2)2PhCOH, by condensation of BzMgCl with desoxybenzoin. Ph2(PhCH2CH2)COH, from PhMgBr and PhCH2CH2CO2Et. Dehydration of Ph2(PhCH2)CCH2OH with P2O2 gave a mixture of Ph2C:CHCH2Ph and Ph(PhCH2)C:CHPh, the latter predominating.

Compt. rend. published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Synthetic Route of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kapche, Gilbert D. W. F.’s team published research in Planta Medica in 77 | CAS: 56317-21-6

Planta Medica published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Category: benzofurans.

Kapche, Gilbert D. W. F. published the artcileHepatoprotective and antioxidant arylbenzofurans and flavonoids from the twigs of Morus mesozygia, Category: benzofurans, the publication is Planta Medica (2011), 77(10), 1044-1047, database is CAplus and MEDLINE.

The chem. investigation of the twigs of Morus mesozygia resulted in the isolation of three new prenylated 2-arylbenzofurans, named moracin KM, LM, and SC (1-3), nine known 2-arylbenzofurans (4-12), and two known flavonoids (13-14). The structures of the new compounds were established as [2”’,3”’:6,7]-(6-(S)-hydroxymethyl-6-methylpyrano)-2-(3,5-dihydroxyphenyl)benzofuran-5-ol (1), [2”,3”:6,7]-(4,7-dihydro-6-methyloxepine)-2-(3-hydroxy-5-methoxyphenyl)benzofuran-5-ol (2), and [2”’,3”:6,7]-(6,6-dimethylpyrano)-2-(3,5-dihydroxyphenyl)benzofuran (3). One of the new compounds, moracin LM (2), displayed modest antioxidant activity, whereas known compounds 4, 13, and 14 showed significant hepatoprotective and antioxidant activities.

Planta Medica published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Category: benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fozing, Christian D. A.’s team published research in Planta Medica in 78 | CAS: 56317-21-6

Planta Medica published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Synthetic Route of 56317-21-6.

Fozing, Christian D. A. published the artcilePhosphodiesterase I-inhibiting Diels-Alder adducts from the leaves of Morus mesozygia, Synthetic Route of 56317-21-6, the publication is Planta Medica (2012), 78(2), 154-159, database is CAplus and MEDLINE.

A new 2-arylbenzofuran derivative, (+)-dimethylsmoracin O (1), and three new Diels-Alder type adducts, mesozygins A-C (2-4), in addition to eight known compounds, artonin I (5), chalcomaracin (6), norartocarpetin (7), moracin L (8), mulberrofuran F (9), moracin M (10), moracin C (11), and morachalcone A (12), were isolated from the leaves of Morus mesozygia Stapf. Structures were elucidated by spectroscopic data analyses. Compounds 2-7 displayed a potent phosphodiesterase I inhibitory activity.

Planta Medica published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Synthetic Route of 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fernandez-Ramos, M. D.’s team published research in Analytical and Bioanalytical Chemistry in 410 | CAS: 596-01-0

Analytical and Bioanalytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Fernandez-Ramos, M. D. published the artcileIonic liquids on optical sensors for gaseous carbon dioxide, Application In Synthesis of 596-01-0, the publication is Analytical and Bioanalytical Chemistry (2018), 410(23), 5931-5939, database is CAplus and MEDLINE.

This work presents a study on the influence of eight different ionic liquids (ILs) in the composition of dry membranes used for gaseous CO2 optical sensing. The presence of CO2 causes a displacement of a colorimetric pH indicator toward its acid form that increases the emission intensity of the luminophore by an inner filter process. The influence of ILs in the membrane on the stability and dynamic behavior-usually the main drawbacks of these sensors-of the membranes was studied. The characterization of the different membranes prepared was carried out and the discussion of the results is presented. In all cases, the response and recovery times improved considerably, with the best case being response times of only 10 s and recovery times of 48 s, compared to response and recovery times of 41 and 100 s, resp., for membranes without IL. The useful life of the detection membranes is also considerably longer than that of membranes that do not include IL, at least 292 days in the best case. The sensing membrane without luminophore and only containing the pH indicator is proposed for the color-based measurement of CO2 using a digital camera for possible use in food-packaging technol. [Figure not available: see fulltext.].

Analytical and Bioanalytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Meier, Michael A. R.’s team published research in Analytical Chemistry in 79 | CAS: 596-01-0

Analytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Related Products of benzofurans.

Meier, Michael A. R. published the artcileStatistical Approach To Understand MALDI-TOFMS Matrices: Discovery and Evaluation of New MALDI Matrices, Related Products of benzofurans, the publication is Analytical Chemistry (2007), 79(3), 863-869, database is CAplus and MEDLINE.

A statistical approach is described to better understand the role of the matrix during a MALDI-TOFMS experiment Potential matrix mols. were selected based on a rational exptl. design and subsequently screened in order to investigate whether a certain compound can act as a matrix for synthetic polymers. The tested compounds were selected from a pool of 11 000 mols. based on descriptor calculations and a subsequent D-optimal design selection procedure. This approach selected 59 organic compounds that were then investigated for their ability to act a matrix for synthetic polymers in MALDI-TOFMS experiments Within this contribution, we focus on the discussion of new MALDI-TOFMS matrixes that were discovered in the course of the screening. At least 10 new matrixes were identified, and 5 of these were subsequently tested more closely with a variety of different synthetic polymers of different mol. weights revealing good to excellent performance of these new matrixes.

Analytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Nika, Maria-Christina’s team published research in Journal of Hazardous Materials in 419 | CAS: 372941-54-3

Journal of Hazardous Materials published new progress about 372941-54-3. 372941-54-3 belongs to benzofurans, auxiliary class Other Aliphatic Heterocyclic,Fluoride,Nitrile,Amine,Benzene,Ester, name is 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile, and the molecular formula is C20H19FN2O2, Quality Control of 372941-54-3.

Nika, Maria-Christina published the artcileNon-target trend analysis for the identification of transformation products during ozonation experiments of citalopram and four of its biodegradation products, Quality Control of 372941-54-3, the publication is Journal of Hazardous Materials (2021), 126401, database is CAplus and MEDLINE.

During ozonation in wastewater treatment plants, ozone reacts with emerging pollutants, which are partially removed through the secondary treatment, as long as, with their biotransformation products, triggering the formation of ozonation transformation products (TPs). Although the transformation of parent compounds (PCs) and their metabolites has been reported in the literature, the probable transformation of biotransformation products has not been investigated so far. This study evaluates the fate of citalopram (CTR) and four of its biotransformation products (DESCTR, CTRAM, CTRAC and CTROXO) during ozonation experiments A Gaussian curve-based trend anal. was performed for the first time for the automated detection of TPs in ozone concentrations ranging from 0.06 to 12 mg/L. In total 46 ozonation TPs were detected; 7 TPs of CTR, 10 of DESCTR, 9 of CTRAM, 12 of CTRAC and 8 of CTROXO and were structurally elucidated based on their high resolution tandem mass spectra interpretation and tandem mass spectra similarity with the resp. PC. Results have demonstrated that the examined compounds follow common transformation pathways in reaction with ozone and that common TPs were formed through the ozonation of different structurally-alike compounds Moreover, the toxicity of the identified TPs was predicted with an inhouse risk assessment program.

Journal of Hazardous Materials published new progress about 372941-54-3. 372941-54-3 belongs to benzofurans, auxiliary class Other Aliphatic Heterocyclic,Fluoride,Nitrile,Amine,Benzene,Ester, name is 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile, and the molecular formula is C20H19FN2O2, Quality Control of 372941-54-3.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Houbion, J. A.’s team published research in Organic Preparations and Procedures International in 1979-02-28 | CAS: 52010-22-7

Organic Preparations and Procedures International published new progress about phthalide hydroxy; hydroxyphthalide; toluate bromination cyclization; formylphenyloxazoline hydrolysis cyclization; oxazolinylbenzaldehyde hydrolysis cyclization. 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Quality Control of 52010-22-7.

Houbion, J. A. published the artcileThe synthesis of unambiguously substituted 3-hydroxyphthalides, Quality Control of 52010-22-7, the main research area is phthalide hydroxy; hydroxyphthalide; toluate bromination cyclization; formylphenyloxazoline hydrolysis cyclization; oxazolinylbenzaldehyde hydrolysis cyclization.

Hydroxyphthalides I (R = 4-, 6-, 7-Cl; 4-, 6-MeO) were obtained in 61-98% yield by photochem. bromination of II followed by hydrolysis. II (R = 4-MeO, 6-NO2) were obtained from R-2-MeC6H3CO2H by successive bromination and cyclization. I (R = 5-Cl, 5-MeO) were obtained in 63-71% yield by hydrolysis of III. III were obtained by ortho metalation-formylation of para substituted 2-aryloxazolines.

Organic Preparations and Procedures International published new progress about phthalide hydroxy; hydroxyphthalide; toluate bromination cyclization; formylphenyloxazoline hydrolysis cyclization; oxazolinylbenzaldehyde hydrolysis cyclization. 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Quality Control of 52010-22-7.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Darling, Stephen D.’s team published research in Journal of Organic Chemistry in 1967 | CAS: 13391-27-0

Journal of Organic Chemistry published new progress about FURAN BENZO REDN; BENZO FURAN REDN; BENZOFURANS LITHIUM AMMONIA REDN. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Recommanded Product: 5-Methoxy-2-methylbenzofuran.

Darling, Stephen D. published the artcileLithium-ammonia reduction of benzofurans, Recommanded Product: 5-Methoxy-2-methylbenzofuran, the main research area is FURAN BENZO REDN; BENZO FURAN REDN; BENZOFURANS LITHIUM AMMONIA REDN.

The reduction of 5-methoxy-2-methylbenzofuran (I), 5-methoxybenzofuran (II), 2,3- dihydro – 5 – methoxy – 2 – methylbenzofuran (III), and 2,3-dihydro-5-methoxybenzofuran (IV) with Li-NH3 systems is described. Furan ring opening was observed in the reduction of I or II when a limited amount of alc. was present in the NH3 solution With excess alc., the corresponding 5-methoxy-2,3,4,7-tetrahydrobenzofuran was formed from each substrate. A side product from the reduction of III was 2,3,4,5,6,7-hexahydro-2-methylbenzofuran (V). 21 references.

Journal of Organic Chemistry published new progress about FURAN BENZO REDN; BENZO FURAN REDN; BENZOFURANS LITHIUM AMMONIA REDN. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Recommanded Product: 5-Methoxy-2-methylbenzofuran.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Tanemura, Kiyoshi’s team published research in Bulletin of the Chemical Society of Japan in 1993-04-30 | CAS: 50551-63-8

Bulletin of the Chemical Society of Japan published new progress about dichlorodicyanobenzoquinone addition benzofuran indole. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, SDS of cas: 50551-63-8.

Tanemura, Kiyoshi published the artcileThe reaction of 2,3-dichloro-5,6-dicyano-p-benzoquinone with benzofurans and indoles, SDS of cas: 50551-63-8, the main research area is dichlorodicyanobenzoquinone addition benzofuran indole.

The reaction of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) with 6-methoxy-3-methylbenzofuran gave carbon-oxygen adduct I. The reaction in less polar solvents such as benzene and CH2Cl2 proceeds faster than that in more polar solvents such as THF and dioxane. In contrast, the reaction of DDQ with indoles II (R1 = H, Cl, Br, OMe, R2 = H; R1 = H, R2 = Me) gave carbon-carbon adducts III. This reaction proceeds rapidly with increasing solvent polarity.

Bulletin of the Chemical Society of Japan published new progress about dichlorodicyanobenzoquinone addition benzofuran indole. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, SDS of cas: 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ni, Yang’s team published research in Organic Chemistry Frontiers in 2021 | CAS: 13391-27-0

Organic Chemistry Frontiers published new progress about Amidation. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Computed Properties of 13391-27-0.

Ni, Yang published the artcileIron-catalyzed cross-dehydrogenative C-H amidation of benzofurans and benzothiophenes with anilines, Computed Properties of 13391-27-0, the main research area is diarylamine preparation; benzofuran aniline cross dehydrogenative amidation iron catalyst; benzothiophene aniline cross dehydrogenative amidation iron catalyst.

An efficient iron-catalyzed cross-dehydrogenative aromatic C-H amidation using DDQ as an oxidant under mild conditions was reported, providing a straightforward access to structurally diverse diarylamines 4-MeC6H4SO2NRR1 [R = 2-butylbenzofuran-3-yl, benzothiophen-3-yl, 4-MeOC6H4, etc.; R1 = 4-MeOC6H4, 3-F-4-MeOC6H3, 4-MeSC6H4, etc.] incorporating benzofuran/benzothiophene motifs. Mechanistic studies indicated that a nitrogen-centered anilino radical was involved in the C-N bond formation.

Organic Chemistry Frontiers published new progress about Amidation. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Computed Properties of 13391-27-0.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem