Wu, Yingnan et al. published their research in Journal of Physical Chemistry Letters in 2020 | CAS: 76-54-0

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Reference of 76-54-0

Enhancing intersystem crossing to achieve thermally activated delayed fluorescence in a water-soluble fluorescein derivative with a flexible propenyl group was written by Wu, Yingnan;Zhao, Yanliang;Zhou, Panwang;Zheng, Daoyuan;Wang, Honglei;Tang, Shanliang;Tian, Jiarui;Yang, Songqiu;Deng, Weiqiao;Han, Keli;Song, Fengling. And the article was included in Journal of Physical Chemistry Letters in 2020.Reference of 76-54-0 This article mentions the following:

It is a challenge to rationally design an organic mol. with thermally activated delayed fluorescence (TADF) due to the intrinsically spin-forbidden transition. Meanwhile, those reported TADF organic mols. have difficulty to be directly applied in the field of biol. and medical imaging because they usually have no water solubility Here, a water-soluble TADF organic mol. DCF-BXJ was developed by introducing a flexible propenyl group into the com. traditional fluorophore DCF (2,7-dichlorofluorescein). The flexible group provides nonradiative rotational motion, which causes an efficient energy level cross between the S1 state and the T2 state of DCF-BXJ. Results of transient absorption spectra and theor. calculations supported that nonradiative rotational motion of the flexible group can enhance intersystem crossing (ISC) and bring out TADF. This work provides a new mechanism explanation for TADF existing in organic mols. In the experiment, the researchers used many compounds, for example, 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0Reference of 76-54-0).

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Reference of 76-54-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem