Synthesis of some benzofuro[3,2-d]pyrimidine derivatives as antibacterial and antifungal agents was written by Sangapure, S. S.;Veeresh, D. H.;Yadav, Bodke. And the article was included in Indian Journal of Heterocyclic Chemistry in 2000.Application In Synthesis of 3-Aminobenzofuran-2-carboxamide This article mentions the following:
Condensation of 3-amino-2-benzofurancarboxamide with aromatic aldehydes in presence of catalytic amount of conc hydrochloric acid gave 2-aryl-3,4-dihydro-4-oxobenzofuro[3,2-d]pyrimidines in a single step. Some 2,4-disubstituted benzofuro[3,2-d]pyrimidines have been synthesized. Benzofuropyrimidine derivatives have been screened for antibacterial and antifungal activity against S. aureus, E. coli and C. albicans. In the experiment, the researchers used many compounds, for example, 3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7Application In Synthesis of 3-Aminobenzofuran-2-carboxamide).
3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Application In Synthesis of 3-Aminobenzofuran-2-carboxamide
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem