Kinetics of the opening and closing of lactone rings. Structural influence. II. Study on ortho substituted phthalides. Application of the Hammett equation was written by Vene, J.;Tirouflet, J.. And the article was included in Bulletin de la Societe Chimique de France in 1954.Name: 5-Methoxyisobenzofuran-1(3H)-one This article mentions the following:
Rate constants, energies of activation and entropy factors for the alk. hydrolysis of phthalides, substituted in the position ortho to the carboxyl were determined The results are analyzed considering the Hammett equation and the latter is found to be applicable to this case. Stearic factors enter into the reaction as they do in the case of the benzoates. In the experiment, the researchers used many compounds, for example, 5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2Name: 5-Methoxyisobenzofuran-1(3H)-one).
5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Name: 5-Methoxyisobenzofuran-1(3H)-one
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem