Synthetic Route of 1563-38-8, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1563-38-8, molcular formula is C10H12O2, introducing its new discovery.
Unsymmetrical bis-[N-alkyl-N-arylcarbamate] sulfide compounds exhibit outstanding miticidal, nematocidal and insecticidal activity, coupled with substantially reduced mammalian toxicity and phytotoxicity. SUMMARY OF THE INVENTION This invention relates to a novel class of unsymmetrical bis-arylcarbamate sulfide compounds and to methods of preparing them. This invention also relates to insecticidal, nematocidal and miticidal compositions comprising an acceptable carrier and an insecticidally or miticidally effective amount of a compound of this invention as well as to a method of controlling insects, mites and nematodes by subjecting them to an insecticidally, miticidally or nematocidally effective amount of a compound of this invention. The bis-carbamate compounds of this invention exhibit wide spectrum high level insecticidal activity as well as relatively low mammalian toxicity. This unique combination of high insecticidal activity and low mammalian toxicity permit the use of the novel unsymmetrical bis-carbamate compounds of this invention in relative safety. DESCRIPTION OF THE INVENTION This invention relates to compounds of the formula: STR1 wherein: R’ and R” are the same or different and are alkyl having from 1 to 4 carbon atoms; R1 and R2 are individually hydrogen or alkyl having from 1 to 4 carbon atoms; R3 is: (A) naphthyl, benzodioxolanyl, tetrahydronaphthyl, indanyl or benzothienyl, all of which may be either unsubstituted or substituted with one or more alkyl groups. (B.) phenyl either unsubstituted or substituted with one or more alkyl having from 1 to 12 carbon atoms, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, dialkylamino or nitro groups; With the proviso that R3 may not include more than eight aliphatic carbon atoms, except as noted. Other compounds which are illustrative of the new compounds of this invention are: N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[3-(1-methylpropyl)phenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[(4-dimethylamino-3,5-xylylmethylcarbamate] sulfide. N-[2,3-dihydro-2-methyl-7-benzofuranylmethylcarbamate] N-[2-isopropoxyphenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranylmethylcarbamate] N-[4-benzothienyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranylmethylcarbamate] N-[5,6,7,8-tetrahydronaphthyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranylmethylcarbamate] N-[3,4,5-trimethylphenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranylmethylcarbamate] N-[4-methylthio-3,5-xylylmethylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranylmethylcarbamate] N-[4-dimethylamino-3-tolyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[4-indanylmethylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[2-ethylthiomethylphenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[2-ethylsulfinylmethylphenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[4-methylsulfinyl-3,5-xylylmethylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[3,5-diisopropylphenyl methylcarbamate] sulfide. N-[2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate] N-[2,2-dimethylbenzodioxolanyl-4-methylcarbamate] sulfide. All of the compounds within the purview of the generic formula set forth above exhibit miticidal and insecticidal activity to a lesser or greater extent. Accordingly, these compounds are extremely useful for the control of insect, nematode and mite pests. Some of these compounds exhibit very high levels of miticidal, nematocidal and insecticidal activity in extremely small dosages while others require larger dosages to be effective. In general, the compounds of this invention are either totally lacking in phytotoxicity or exhibit only minimal phytotoxicity with respect to economically important crop species. In addition, these compounds exhibit substantially reduced levels of mammalian toxicity as compared to known pesticidal compounds having a comparable spectrum of activity against insect, arachnid and nematode pests. Preferred because of their higher levels of miticidal and insecticidal activity are the compounds of this invention in which: R’, r”, r1 and R2 are methyl; R3 is naphthyl, or phenyl substituted with one or more alkoxy, alkyl, alkylthio or dialkylamino groups. The unsymmetrical bis-[N-alkyl-N-arylcarbamate] sulfide compounds of this invention can be conveniently prepared by a variety of methods. One preferred method is illustrated by the reaction scheme set forth below in which R’, R”, R1, R2 and R3 are as described above, except as noted: STR2 METHOD I is a two-step reaction sequence which can be conducted either in-situ or the carbamate-sulfenyl carbamoyl halide intermediate (I…
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1563-38-8 is helpful to your research. Synthetic Route of 1563-38-8
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2292O – PubChem