Top Picks: new discover of 16859-59-9

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 16859-59-9, you can also check out more blogs about16859-59-9

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 16859-59-9. Introducing a new discovery about 16859-59-9, Name is 3-Hydroxyisobenzofuran-1(3H)-one

Synthesis of Enantioenriched Phthalide and Isoindolinone Derivatives from 2-Formylbenzoic Acid

Transformations of 2-formylbenzoic acid provide direct access to a series of heterocyclic organic compounds such as phthalides and isoindolinones. Here, we use (+)-cinchonine as a catalyst in conjunction with nonafluoro-tert-butanol as a hydrogen-bond donor to afford enantiomerically enriched acylated 3-hydroxyphthalides with up to 99% yield and 90% ee through dynamic kinetic resolution. Moreover, various 3-alkoxyphthalides as well as 2-alkyl-3-hydroxy-1-isoindolinones were synthesized from 2-formylbenzoic acid.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 16859-59-9, you can also check out more blogs about16859-59-9

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1487O – PubChem