Tirouflet, Jean et al. published their research in Bull. soc sci. Bretagne Spec. in 1951 | CAS: 4741-62-2

5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.COA of Formula: C9H8O3

Syntheses of substituted phthalides and substituted phthalic anhydrides and a study of the reactivity of the carbonyl group. III. Kinetic study of the alkaline hydrolysis of substituted phthalides. 1. Alkaline hydrolysis of phthalides was written by Tirouflet, Jean. And the article was included in Bull. soc sci. Bretagne Spec. in 1951.COA of Formula: C9H8O3 This article mentions the following:

The rate constants for the alk. hydrolysis of many substituted phthalides have been determined at 25.0° in 15.1 weight-% EtOH in CO2-free water by titrating the excess NaOH with 0.01N H2SO4 and phenolphthalein; 0.0005 mole of the substituted phthalide was used in 250 cc. solution, although check runs with 0.02 and 0.008 mole showed no significant change. The solutions of the phthalides were tested after hydrolysis with AgNO3 solution, but no secondary reactions involving halogen displacements were found. Similarly, no hydrolysis of AcNH groups occurred, as shown by quant. recovery of AcNH-substituted acid alcs. after hydrolysis. The following average rate constants were obtained for the phthalides [substituent, K (min.-1 mole/liter-1)]: H, 11.7; 4-NH2, 8.75; 5-NH2, 0.47; 6-NH2, 6.7; 7-NH2, 0.60; 4-AcNH, 28.8; 5-AcNH, 7.6; 6-AcNH, 21.3; 7-AcNH, 13.3; 4-MeO, 17.6; 5-MeO, 2.5; 6-MeO, 13.65; 6,7-(MeO)2, 7.9; 4-EtO 19.4 (estimated value because of precipitation of supersaturated phthalide solution prior to complete reaction); 5-EtO, 2.58; 6-EtO, 11.9; 4-O2N, 184; 5-O2N, 398; 6-O2N, 246; 5-NC, 275; 6-NC, 161; 4-Cl, 54.3; 5-Cl, 25.2; 6-Cl, 47.6; 7-Cl, 50.3; 4-Br, 50.6; 5-Br, 27.0; 6-Br, 48.4; 7-Br, 43.4; 4-I, 47.1; 5-I, 30; 6-I, 49.1; 7-I, 32.1; 3-Me, 6.5; 3,4-Me(H2N), 3.3. In the experiment, the researchers used many compounds, for example, 5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2COA of Formula: C9H8O3).

5-Methoxyisobenzofuran-1(3H)-one (cas: 4741-62-2) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.COA of Formula: C9H8O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem