Synthesis, characterization and biological activities of some new pyrimidines and isoxazoles bearing benzofuran moiety was written by Tirlapur, Vijay Kumar;Gandhi, Narasimha;Basawaraj, Raga;Rajendra Prasad, Y.. And the article was included in International Journal of ChemTech Research in 2010.COA of Formula: C10H7BrO2 This article mentions the following:
1-(5-Bromo-1-benzofuran-2-yl)-3-(substituted phenyl)-prop-2-en-1-one 2a-e were prepared by the reaction of 5-bromo-2-acetylbenzofuran 1 with different aromatic aldehydes in presence of alkali. Reaction of 2a-e with urea, thiourea and hydroxylamine hydrochloride to gave 4-(5-bromo-1-benzofuran-2-yl)-6-(substituted phenyl)-pyrimidine-2-ol 3a-e, 4-(5-bromo-1-benzofuran-2-yl)-6-(substituted phenyl)-pyrimidine-2-thiol 4a-e and 3-(5-bromo-1-benzofuran-2-yl)-5-(substituted phenyl)-4,5 dihydroisoxazole 5a-e resp. The characterization of all synthesized compounds was done by anal. and spectral studies. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6COA of Formula: C10H7BrO2).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.COA of Formula: C10H7BrO2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem