Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 767291-67-8, is researched, Molecular C20H42N2, about The asymmetric alkylation of dimethylhydrazones; intermolecular chirality transfer using sparteine as chiral ligand, the main research direction is sparteine chiral catalyst stereoselective alkylation hydrazone.Synthetic Route of C20H42N2.
An asym. alkylation of ketones represents a fundamental transformation in organic chem. Chiral auxiliaries have been used almost exclusively for this transformation. Herein the authors describe a strategy for the generation of enantiomerically enriched α-alkylated ketones up to an er of 83:17, using a chiral ligand protocol. The synthesis of the target compounds was achieved using 3-pentanone 2,2-dimethylhydrazone, 4-heptanone 2,2-dimethylhydrazone, Cycloheptanone 2,2-dimethylhydrazone, benzyl bromide,1-iodopentane, 1-iodohexane, allyl, bromide as starting materials. (7R,7AR,14R,14aS)-dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine [alkaloid, (+)-sparteine] and (7S,7aR,14S,14aS)-dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine [(-)-sparteine] were used as chiral ligands. The title compounds thus formed included (2R)-2-methyl-1-phenyl-3-pentanone, (4S)-4-methyl-3-nonanone, (2R)-2-(2-propen-1-yl)cycloheptanone, (2S)-2-(2-propen-1-yl)cycloheptanone.
After consulting a lot of data, we found that this compound(767291-67-8)Synthetic Route of C20H42N2 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem