Tag: 284.106

Ekambaram, Ramesh et al. published their research in RSC Advances in 2015 | CAS: 330555-71-0

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Product Details of 330555-71-0

PIM kinase-responsive microsecond-lifetime photoluminescent probes based on selenium-containing heteroaromatic tricycle was written by Ekambaram, Ramesh;Babu Manoharan, Ganesh;Enkvist, Erki;Ligi, Kadri;Knapp, Stefan;Uri, Asko. And the article was included in RSC Advances in 2015.Product Details of 330555-71-0 This article mentions the following:

A new structural fragment was synthesized for construction of protein binding-responsive photoluminescent probes. In complex with protein kinases of the PIM family, bisubstrate inhibitors containing benzo[4,5]seleno[3,2-d]pyrimidin-4-one moiety revealed microsecond-lifetime phosphorescence emission after pulse excitation with near-UV radiation. The phosphorescence signal was substantially (more than 50-fold) amplified by a covalently bound fluorescent dye (PromoFluor-555 or PromoFluor-647) whose absorption spectrum well overlapped with the phosphorescence emission spectrum of the selenium-containing heteroaromatic tricycle. The developed organic small-mol. long-lifetime photoluminescence probes possess subnanomolar affinity towards kinases of the PIM family and reveal especially strong emission signal with PIM-2 isoenzyme. The developed probes have potential to be used for monitoring of activity of PIM kinases for diagnosis of cancer. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0Product Details of 330555-71-0).

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Product Details of 330555-71-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Yamuna, A. J. et al. published their research in International Journal of Pharmacy and Pharmaceutical Sciences in 2013 | CAS: 330555-71-0

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.COA of Formula: C11H10BrNO3

Synthesis, characterization and biological activities of some benzofuropyrimidine derivatives was written by Yamuna, A. J.;Vaidya, Vijayvithal P.;Shruthi, Eshwarappa;Mahadevan, Kittappa M.. And the article was included in International Journal of Pharmacy and Pharmaceutical Sciences in 2013.COA of Formula: C11H10BrNO3 This article mentions the following:

A series of new benzofuropyrimidinone derivatives I [Ar = C6H5, 2-ClC6H4, 4-ClC6H4, etc.; R = H, Me] were synthesized by using Et 3-amino-5-bromo-benzofuran-2-carboxylate (II) as a starting material. Amino ester II was converted into its hydrazide by reacting with hydrazine hydrate, which upon treatment with various aldehydes and ketones gave corresponding Schiff bases III [Ar = C6H5, 2-ClC6H4, 4-ClC6H4, etc.; R = H, Me]. The desired compounds I were obtained by reacting Schiff bases III with tri-Et orthoformate. The compounds I were evaluated for their antimicrobial activity by cup plate method and antioxidant activity by DPPH radical scavenging method. Some of the compounds exhibited considerable antimicrobial activities and compounds I [R = 4-MeOC6H4, 4-HOC6H4] were found to be excellent in scavenging DPPH radical at 50 μg and also retained almost same activity in 100 μg. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0COA of Formula: C11H10BrNO3).

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.COA of Formula: C11H10BrNO3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Yamuna, A. J. et al. published their research in International Journal of Pharmacy and Pharmaceutical Sciences in 2013 | CAS: 330555-71-0

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.COA of Formula: C11H10BrNO3

Synthesis, characterization and biological activities of some benzofuropyrimidine derivatives was written by Yamuna, A. J.;Vaidya, Vijayvithal P.;Shruthi, Eshwarappa;Mahadevan, Kittappa M.. And the article was included in International Journal of Pharmacy and Pharmaceutical Sciences in 2013.COA of Formula: C11H10BrNO3 This article mentions the following:

A series of new benzofuropyrimidinone derivatives I [Ar = C6H5, 2-ClC6H4, 4-ClC6H4, etc.; R = H, Me] were synthesized by using Et 3-amino-5-bromo-benzofuran-2-carboxylate (II) as a starting material. Amino ester II was converted into its hydrazide by reacting with hydrazine hydrate, which upon treatment with various aldehydes and ketones gave corresponding Schiff bases III [Ar = C6H5, 2-ClC6H4, 4-ClC6H4, etc.; R = H, Me]. The desired compounds I were obtained by reacting Schiff bases III with tri-Et orthoformate. The compounds I were evaluated for their antimicrobial activity by cup plate method and antioxidant activity by DPPH radical scavenging method. Some of the compounds exhibited considerable antimicrobial activities and compounds I [R = 4-MeOC6H4, 4-HOC6H4] were found to be excellent in scavenging DPPH radical at 50 μg and also retained almost same activity in 100 μg. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0COA of Formula: C11H10BrNO3).

Ethyl 3-amino-5-bromobenzofuran-2-carboxylate (cas: 330555-71-0) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.COA of Formula: C11H10BrNO3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem