Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide, is researched, Molecular C19H19N2NaO2, CAS is 129-18-0, about Analysis of drug decomposition products. Part 32. Spectrophotometric method for evaluating the stability of phenylbutazone and aminophenazone in the preparation “”Rheumopyrin””.Quality Control of Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide.
Na phenylbutazone [129-18-0] and aminophenazone [58-15-1] were determined simultaneously by their resp. maximum absorption at 241 and 265 nm. Both the quant. spectrophotometric anal. and qual. anal. by thin-layer chromatog. on silica gel indicated the presence of decomposition products of phenylbutazone but not aminophenazone in the preparation Rheumopyrine [8066-94-2].
《Analysis of drug decomposition products. Part 32. Spectrophotometric method for evaluating the stability of phenylbutazone and aminophenazone in the preparation “”Rheumopyrin””》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide)Quality Control of Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem