The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Congo red interaction with alpha-proteins.》. Authors are Sereikaite, Jolanta; Bumelis, Vladas-Algirdas.The article about the compound:Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinatecas:70539-42-3,SMILESS:O=C(ON1C(CCC1=O)=O)CCC(OCCOC(CCC(ON2C(CCC2=O)=O)=O)=O)=O).Formula: C18H20N2O12. Through the article, more information about this compound (cas:70539-42-3) is conveyed.
The ability of Congo red to form complexes with alpha-proteins, human growth hormone and human interferon-alpha2b, was found by absorption difference spectroscopy. A human growth hormone-Congo red complex was isolated by gel-permeation chromatography, and its visible absorption spectrum was registered in comparison to free dye. The ability of Congo red to induce dimerization of human growth hormone was demonstrated using chemical cross-linking agents 1,3,5-triacryloyl-hexahydro-s-triazine and ethylene glycol bis(succinimidylsuccinate).
《Congo red interaction with alpha-proteins.》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate)Formula: C18H20N2O12.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem