The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Antacids. II. Gel of aluminum hydroxide》. Authors are Okasaki, Kanzo; Tanabe, Shizuko.The article about the compound:Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-idecas:129-18-0,SMILESS:O=C(N(C1=CC=CC=C1)N2C3=CC=CC=C3)[C-](CCCC)C2=O.[Na+]).Synthetic Route of C19H19N2NaO2. Through the article, more information about this compound (cas:129-18-0) is conveyed.
The antacidic effectiveness of Al(OH)3 is studied by the modified Fuchs’ method. The efficacy of the spray-dried gel is better than the one dried at low temperature The efficacy decreases in the order liquid gel, dried gel, and granules. Even if dried gel is suspended in water, its efficacy is not improved. The efficacy is related not only to the size of particles, but also to aging. Mech. mixture of dried gel and other antacids, such as Mg salts, did not improve the antacid efficacy, but such mixtures treated with water showed good result.
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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem