Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 129-18-0, is researched, SMILESS is O=C(N(C1=CC=CC=C1)N2C3=CC=CC=C3)[C-](CCCC)C2=O.[Na+], Molecular C19H19N2NaO2Journal, Article, Experientia called Comparative dominant lethal studies with phenylbutazone, thio-TEPA, and methyl methanesulfonate [MMS] in the mouse, Author is Machemer, L.; Hess, R., the main research direction is phenylbutazone lethal mutation; thio TEPA lethal mutation; methanesulfonate lethal mutation; spermatogenesis thio TEPA; spermatozoa methanesulfonate.Safety of Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide.
Thio-TEPA (I) [52-24-4] (5 and 10 mg/kg) and Me methanesulfonate (II) [66-27-3] (50 and 100 mg/kg) given i.p. to male rats before mating induced dominant lethal effects, whereas Na phenylbutazone (III Na salt) [129-18-0] (50 and 100 mg/kg, i.p.) did not. I was highly effective on the postmeiotic stages of spermatogenesis, whereas I was highly effective on epididymal and testicular spermatozoa.
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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem