Properties and Exciting Facts About Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 143878-29-9, you can also check out more blogs about143878-29-9

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 143878-29-9. Introducing a new discovery about 143878-29-9, Name is Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

SAR studies of 7-phenylpyrrolo[1,2-alpha]pyrimid-4-ones 1 and 2, and 2-phenylimidazolo[1,2-alpha]-pyrimidines 3 and 4, as nonpeptide human GnRH receptor antagonists, lead us to believe that the aromatic ring at position-2 of 4 is no longer crucial for the binding once an aryl group is incorporated at postion-6. We report here the use of a 2-alkyl group on the imidazolo[1,2-alpha]- pyrimidone core to generate potent GnRH receptor antagonists. This discovery enabled us to obtain smaller but equally potent GnRH receptor antagonists.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 143878-29-9, you can also check out more blogs about143878-29-9

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4100O – PubChem