Chemistry is traditionally divided into organic and inorganic chemistry. Computed Properties of C8H5BrO, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 128851-73-0
The synthesis and structure-activity relationships of a series of 5,7-diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acids are described. Our efforts have been focused on modification of the aryl ring at the 5-position and the alkyl substituent at the 2-position of the bottom 4-methoxyphenyl ring in an effort to develop orally available ETA selective antagonists with safer profiles in terms of the P-450 enzyme inhibitory activity. Incorporation of a hydroxymethyl group as an alkyl substituent in methylenedioxyphenyl and 6-dihydrobenzofuran derivatives led to the identification of orally bioavailable ETA selective antagonists 1f and 7f. These compounds also showed not only excellent binding affinity (IC50<0.10nM, more than 800-fold selectivity for the ETA receptor over the ETB receptor) but also sufficient oral bioavailability, 48% and 56%, respectively, in rats. Furthermore, these compounds did not exhibit either competitive or mechanism-based inhibition of human cytochrome P450 enzymes. If you are interested in 128851-73-0, you can contact me at any time and look forward to more communication. Computed Properties of C8H5BrO
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3315O – PubChem