Alkaline hydrolysis of the methyl esters of benzo[b]furan-2- and 3-carboxylic acid, benzo[b]thiophene-2- and 3-carboxylic acid, and indole-2- and 3-carboxylic acid was written by Feinstein, A.;Gore, Peter H.;Reed, George Leonard. And the article was included in Journal of the Chemical Society [Section] B: Physical Organic in 1969.Electric Literature of C10H8O3 This article mentions the following:
The rates of alk. hydrolysis of carboxylic acid Me esters, in 70% dioxane follow the sequence 3-benzo[b]furyl >2-benzo[b]furyl >2-benzo[b]thienyl > indol-2-yl > indol-3-yl > phenyl > 3-benzo[b]thienyl. The effect of benzosubstitution on the rates of hydrolysis was determined for furan, thiophene, and pyrrole esters; it ranges from a rate enhancement of ∼200 (for pyrrol-2-yl) to a 70% rate reduction (for 3-thienyl). In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Electric Literature of C10H8O3).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Electric Literature of C10H8O3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem