Application of 83528-03-4, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 83528-03-4, molcular formula is C8H7NO2, introducing its new discovery.
Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi-triptolide
Two series of novel C14 heterocycle substituted epi-triptolide derivatives as potential anticancer agents were synthesized and tested for their cytotoxicity against SKOV-3 and PC-3 tumor cell lines. The introduction of C14beta-aryl heterocycle aminomethyl substituent to the leading compound was found to be an effective modification method to retain the potent anticancer activity. Meanwhile, the series of epi-triptolide derivatives (21-40) with C14alpha-hydroxyl group, still retained the natural product’s cytotoxicity. This is apparently challenges the classical structure-activity relationship of triptolide that considers the C14beta-hydroxyl group to be essential for its anticancer activity.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 83528-03-4 is helpful to your research. Application of 83528-03-4
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1351O – PubChem