Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of Benzo[b]furan-2-carboxaldehyde. Introducing a new discovery about 4265-16-1, Name is Benzo[b]furan-2-carboxaldehyde
Na+-glucose cotransporter inhibitors as antidiabetic agents. II. Synthesis and structure-activity relationships of 4′-dehydroxyphlorizin derivatives
A novel series of 4′-dehydroxyphlorizin derivatives was synthesized and the effects of these compounds on urinary glucose excretion were evaluated in rats. There was a strict structural requirement for activity. Introduction of a small substituent or a fiat ring at the 3- and/or the 4-position on the A ring was permissible, but any change at the bridge part between the A and B rings or in the sugar moiety resulted in complete loss of activity. The 6′- OH group on the B ring was also necessary, and even small structural modifications of the 6′-OH group reduced the activity considerably. Among the compounds synthesized, the 5-benzofuryl derivative 25 was the most potent and was selected as a new lead for further structure-activity relationship investigations.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of Benzo[b]furan-2-carboxaldehyde, you can also check out more blogs about4265-16-1
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H854O – PubChem