With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4265-16-1,Benzo[b]furan-2-carboxaldehyde,as a common compound, the synthetic route is as follows.,4265-16-1
6-Aminocoumarin (1.0 mmol) and benzofuran-2-carbaldehyde (1.2 mmol) were refluxed in absolute ethanol (15 mL) for 4 hours, then naturally cooled to room temperature, and then hydrobored under ice bath. Sodium (2.5 mmol), after reacting for 3 hours, concentrated under reduced pressure to remove ethanol, extracted with dichloromethane, washed with water, and then evaporated. 1) A pale yellow solid (258 mg, yield: about 88.5%) was obtained as a benzofuran-substituted coumarin amine derivative of the formula I.
4265-16-1 Benzo[b]furan-2-carboxaldehyde 61341, abenzofuran compound, is more and more widely used in various.
Reference£º
Patent; Yangzhou Industry Polytechnic College; Yang Luyu; Chen Huajin; (6 pag.)CN110105345; (2019); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem