Derayea, Sayed M. et al. published their research in Microchemical Journal in 2020 | CAS: 38183-12-9

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.COA of Formula: C17H10O4

A review on the use of fluorescamine as versatile and convenient analytical probe was written by Derayea, Sayed M.;Samir, Ebtihal. And the article was included in Microchemical Journal in 2020.COA of Formula: C17H10O4 This article mentions the following:

Fluorescamine (FSA) has been widely applied for the determination of several classes of compounds containing amino groups. The estimated substances included pharmaceutical compounds, pesticides, amino acids, peptides and proteins. In addition, the activities of some enzymes were also monitored by FSA assay. The employed techniques mainly included spectrofluorimetry, as spray reagent in TLC, a derivativzation reagent in HPLC and capillary electrophoresis. Although there are many other reagents for detecting primary amino group containing compounds, FSA is advantageous as the reagent itself and its hydrolytic product are non-fluorescent. While other reagents such as NBD-Cl, dansyl chloride and o-phthaldehyde have a native fluorescence and their hydrolytic products are indeed fluorescent. In addition, the involved reaction is very fast and carried out at ambient temperature However, the sensitivity of FSA anal. is much lower than these reagents. The sensitivity of the reagent could be enhanced by the proper selection of the diluting solvent, addition of surfactants or extraction with water immiscible solvent. The present article represents a comprehensive review for the application of FSA as a reagent in chem. and biochem. anal. since its discovery until now. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9COA of Formula: C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.COA of Formula: C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem