65399-05-5, 5-Aminophthalide is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,65399-05-5
20 g (0.13 mol) of 5-aminoisobenzofuranone, 30 ml of 47% HBr solution was added to a 250 ml three-necked flask, and the temperature was slowly controlled at 0 C.Then slowly adding 5 ml of an aqueous solution of sodium nitrite, wherein sodium nitrite contains 10.16 g (0.14 mol), and stirring for 1 h;20.56g (0.14mol) of cuprous bromide is dissolved in 5ml of 47% hydrobromic acid solution, slowly added dropwise to the diazonium salt solution prepared above, and reacted at room temperature for 1h-3h;Filtration, washing with water and recrystallization from isopropanol gave a white powder, i.e., 5-Bromophthalide, 21.6 g, yield 76.8%.
65399-05-5 5-Aminophthalide 720669, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Patent; Changchun University Of Technology; Shi Fuqiang; Ye Peng; (5 pag.)CN108383833; (2018); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem