Category: 569-31-3

Related Products of 569-31-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4. In a Article，once mentioned of 569-31-3

The present study aims to investigate the influence of metabolic behavior by the introduction of bromo atom into the structure of noscapine. Oral gavage of 50 mg/kg bromo-noscapine for 6- to 8-week-old male mice with C57BL/6 background resulted in the detection of the metabolite undergoing cleavage of methylenedioxy group (II), demethylated bromo-noscapine (III, IV), meconine (V), bromo-cotarnine (VI), bisdemethylated bromo-noscapine (VII), and their corresponding glucuronides (G1-G4) in urine, feces, and serum (24 h). In vitro human liver microsomes or mice liver microsomes incubation system can also give the formation of phase I metabolites. Furthermore, the phase I drug-metabolizing enzymes involved in the metabolism of bromo-noscapine was screened. Many CYP isoforms were involved in the formation of metabolite II, and CYP3A4, CYP1A1, CYP2C19, and CYP2D6 were major CYP isoforms. All the determined CYP isoforms showed the catalytic activity towards the formation of metabolites III, V, and VI. The major CYP isoforms involved in the catalytic formation of metabolite IV were CYP2C19, CYP2D6, and CYP2E1. In conclusion, to date, many structural derivatives of noscapine have been synthesized based on the efficiency. However, the metabolic behavior remains to be elucidated, and the present study gave an example through the investigation of metabolic pathway of bromo-noscapine. The introduction of bromo atom into the structure of noscapine did not alter the metabolites profile, but changed the drug-metabolizing enzyme profiles.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 569-31-3. In my other articles, you can also check out more blogs about 569-31-3

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Benzofuran – Wikipedia,
Benzofuran | C8H3159O – PubChem

Application of 569-31-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4. In a Article£¬once mentioned of 569-31-3

Transpositive Tandem Annulation of Phthalides with Allene Carboxylates: Regioselective Synthesis of Arylnaphthalene Lignans

Allene carboxylates, scarcely used as Michael acceptors, serve as acceptors in the annulation with phthalides in the presence of LDA and provide a one-pot synthesis of naphtho[c]furanones in very good yields. This tandem annulation is proposed to proceed via transposition of the hydroxy group resulting from the initial annulation.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 569-31-3. In my other articles, you can also check out more blogs about 569-31-3

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Benzofuran – Wikipedia,
Benzofuran | C8H3140O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 6,7-Dimethoxy-3H-1-isobenzofuranone, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 569-31-3

A NEW SYNTHESIS OF PHTHALIDES THROUGH beta-SCISSION OF BENZOCYCLOBUTENOL HYPOIODITES

A simple new method for the synthesis of phthalides and their 3-alkyl 3,3′-spiroalkyl derivatives including (+/-)-3-butylphthalide, a racemic form of a constituent of celery oil, through the beta-scission of alkoxyl radicals generated from hypoiodites of benzocyclobutenols by the photolysis, is described.

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Benzofuran – Wikipedia,
Benzofuran | C8H3135O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C10H10O4, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4

PHOTOREACTION OF PHTHALIMIDES POSSESSING AN ORTHO-METHYLPHENYL GROUP IN THEIR N-SIDE CHAIN. SYNTHESIS OF TETRACYCLIC NITROGEN HETEROCYCLES

Upon irradiation phthalimides (5 and 8) possesing o-methylphenyl group in their N-side chain gave mainly the tetracyclic ring systems (9 and 10).It was shown that the photocyclization occurs at epsilon- or zeta-position across the carbons of the benzene ring (B-ring).

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Benzofuran – Wikipedia,
Benzofuran | C8H3138O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 569-31-3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4

Studies on Carboxylation of Alkoxy-Substituted Benzyl Alcohols via Direct Lithiation and Bromine-Lithium Exchange: Synthesis of Phthalides and Phthalideisoquinoline Alkaloids

Conversion of alkoxy-substituted benzyl alcohols to the corresponding phthalides by carboxylation via ortho lithiation and bromine-lithium exchange was studied.The method was applied to the key step in the synthesis of phthalideisoquinoline alkaloids.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 569-31-3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 569-31-3, in my other articles.

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Benzofuran – Wikipedia,
Benzofuran | C8H3151O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Quality Control of 6,7-Dimethoxy-3H-1-isobenzofuranone, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 569-31-3, name is 6,7-Dimethoxy-3H-1-isobenzofuranone. In an article£¬Which mentioned a new discovery about 569-31-3

NEW SHORT STEP GENERAL SYNTHESIS OF ISOBENZOFURAN-1(3H)-ONES (PHTALIDES) BASED ON A SINGLE OR DOUBLE beta-SCISSION OF ALKOXYL RADICALS GENERATED FROM 1-ETHYL-BENZOCYCLOBUTEN-1-OLS AND FROM 1,3-DIHYDROISOBENZOFURAN-1-OLS; SYNTHESIS OF SOME NATURAL PHTHALIDES

New general methods are described for the synthesis of phthalides, 3-monosubstituted, and 3,3-disubstituted phthalides including naturally-occuring phthalides such as pierardine based on a regioselective single or double beta-scission of the alkoxyl radicals generated by the photolysis of the hypoiodites of 1-ethyl-benzocyclobuten-1-ols or 1,2-catacondensed benzocyclobuten-1-ols or 1,3-dihydro-1,3-alkanoisobenzofuran-1-ols.The formation paths of the phthalides, which involve a regioselective single or double beta-scission of the alkoxyl radicals generated from 1-alkylbenzocyclobuten-1-ols and from catacondensed benzocyclobuten-1-ols, are discussed.Key Words: Synthesis of Phthalides; Alkoxy Radicals; Mercury(II)oxide-Iodine Reagent; Photolysis; Double beta-Scission

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Benzofuran – Wikipedia,
Benzofuran | C8H3134O – PubChem

Reference of 569-31-3, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4. In a article£¬once mentioned of 569-31-3

Synthesis of phthalideisoquinolines by direct coupling of phthalide anions with 3,4-dihydroisoquinolinium salts

The condensation of phthalide anions, derived from phthalide itself and from its 6,7- and 5,6-dimethoxy derivatives, with 6,7-dimethoxy-2-methyl-3,4-dihydroisoquinoline is described.The reaction products obtained in ca. 40percent yield are easily separable mixtures of substituted (+/-)-erythro and (+/-)-threo-phthalidetetrahydroisoquinolines.The reaction is potentially useful for synthesis of naturally occurring alkaloids of this family.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 569-31-3

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Benzofuran – Wikipedia,
Benzofuran | C8H3144O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 6,7-Dimethoxy-3H-1-isobenzofuranone, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4

ANALOGS OF PYRIMIDINE NUCLEOSIDES. 19. SYNTHESIS, ANTINEOPLASTIC ACTIVITY, AND KINETICS OF THE HYDROLYSIS OF 1-(3-PHTHALIDYL)-5-FLUOROURACILS

1-(3-Phthalidyl)-5-fluorouracils were synthesized by alkylation of 2,4-bis(trimethylsilyl)-5-fluorouracil with substituted 3-bromophthalides, and the rate constants for hydrolysis at pH 8.0-11.5 were determined.The antineoplastic activity of a number of the compounds was established, and it was assumed that there is a relationship between the biological activity and the rate of hydrolysis.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: 6,7-Dimethoxy-3H-1-isobenzofuranone, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 569-31-3, in my other articles.

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Benzofuran – Wikipedia,
Benzofuran | C8H3160O – PubChem

Electric Literature of 569-31-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 569-31-3, Name is 6,7-Dimethoxy-3H-1-isobenzofuranone, molecular formula is C10H10O4. In a Article£¬once mentioned of 569-31-3

Central Nervous System Active Compounds. XII. The Synthesis and Properties of 3-Dimethylaminomethylene Phthalides

Isobenzofuran-1(3H)-one (phthalide), and its derivatives react with dimethylformamide dimethyl acetal to form 3-dimethylaminomethyleneisobenzofuran-1-one and minor amounts of the corresponding internal betaine 2-(2-carboxylatophenyl)ethynyltrimethylammonium.The use of the t-butoxy-bis(dimethylamino)methane allows the isolation of the corresponding aminal, which readily loses dimethylamine on recrystallization.The dimethylamino group in the title compounds is replaceable by amino, hydrazino or hydroxy groups in mildly acidic solution. 3-Formylphthalide, the tautomer of the last-named product, could be isolated as the 2,4-dinitrophenylhydrazone.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 569-31-3. In my other articles, you can also check out more blogs about 569-31-3

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3128O – PubChem