Simple exploration of 5-Hydroxyisobenzofuran-1(3H)-one

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Electric Literature of 55104-35-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 55104-35-3, 5-Hydroxyisobenzofuran-1(3H)-one, introducing its new discovery.

The invention discloses 4 – oxo – 2, 3 – dihydro quinoline compounds by oxidation method, it to 4 – oxo – 2, 3 – dihydro quinoline compound as raw material, the organic solvent is added, an acidulant and oxidizing agent, in the 50 – 85 C oxidize under the reaction, the reaction solution after the reaction is finished after treatment to obtain 4 – hydroxy quinoline compounds. Preparation method of this invention using different raw materials of simple and easy to obtain, are […], source is wide, and the price is low; and the preparation method is simple, easy to operate, and the yield is high, compared with previous 4 – oxo – 2, 3 – dihydro quinoline compounds by oxidation process more efficient, and after treatment is more simple advantages, the industrialization of the products is particularly important. (by machine translation)

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H1516O – PubChem

New explortion of 5-Hydroxyisobenzofuran-1(3H)-one

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A variety of 1-arylazetidin-2-ones were treated with trifluoroacetic acid under reflux, methanesulphonic acid at 100 deg C, or conc. sulphuric acid to give the corresponding 2,3-dihydro-4(1H)-quinolones via acyl migration and N-CO fission.In the case of 1-(3-substituted phenyl)azetidin-2-ones, two positional isomeric products, 5- and 7-substituted 2,3-dihydro-4(1H)-quinolones were obtained. 4-Methyl, 4-ethoxycarbonyl, and 4-piperidin-2-yl-1-arylazetidin-2-ones and their analogues were also converted into the corresponding 2-substituted 2,3-dihydro-4(1H)-quinolones under acidic conditions.The 3-substituted 1-phenylazetidin-2-ones (36) and (37) were converted into the furo<3,2-c>quinoline systems (38) and (40), respectively, by application of this method.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H1517O – PubChem

Top Picks: new discover of 55104-35-3

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C8H6O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 55104-35-3, Name is 5-Hydroxyisobenzofuran-1(3H)-one, molecular formula is C8H6O3

Synthesis of 2,3-dihydro-4(1H)-quinolones and the corresponding 4(1H)-quinolones via low-temperature fries rearrangement of N-arylazetidin-2- ones

N-Arylazetidin-2-ones of the general form 1, which are readily prepared by GoldbergBuchwald-type copper-catalyzed coupling of N-unsubstituted azetidin-2-ones with the relevant aryl halide or using Mitsunobu cyclization processes, undergo smooth Fries-rearrangement in triflic acid at 018C to give the isomeric 2,3-dihydro-4(1H)-quinolones (2). Dehydrogenation of the latter compounds using 10% Pd on C in 1.0M aqueous sodium hydroxide/propan-2-ol mixtures at ca. 82C provides the corresponding 4(1H)-quinolones (3).

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1518O – PubChem

Awesome Chemistry Experiments For 5-Hydroxyisobenzofuran-1(3H)-one

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Application of 55104-35-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 55104-35-3, 5-Hydroxyisobenzofuran-1(3H)-one, introducing its new discovery.

Structure-activity relationships of antimalarial indolo<3,2-c>quinolines <1,2>

Structure-activity relationships have been ascertained and chemical metodology developed for a series of antimalarial 3-chloroindolo<3,2-c>quinoline-5-oxides.The basic side chain as well as the ring N-oxide are critical for antimalarial activity as is a bromine or chlorine in position 3.Substitution at positions 7,8,9,10 in not essential, although the most potent analog in our studies was the 8-nitro compound 4vv. indolo<3,2-c>quinolines <1,2> / antimalarial agents

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1519O – PubChem

Discovery of 55104-35-3

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Synthetic Route of 55104-35-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.55104-35-3, Name is 5-Hydroxyisobenzofuran-1(3H)-one, molecular formula is C8H6O3. In a Patent£¬once mentioned of 55104-35-3

Process for the preparation of quinolin-4-ones

1,2,3,4-Tetrahydroquinolin-4-ones of the formula: STR1 wherein R represents a hydrogen or halogen atom, an alkyl radical (1 to 4 carbon atoms), an alkoxy radical (1 to 4 carbon atoms) or the trifluoromethyl radical, and R1 represents a hydrogen atom, an alkyl radical (1 to 4 carbon atoms) or the trifluoromethyl radical, are prepared by cyclizing a 3-anilinopropionic acid of the formula: STR2 (wherein R and R1 are as hereinbefore defined) in a mixture of hydrofluoric acid and boron trifluoride. The quinolinone products are useful intermediates in the synthesis of therapeutically active substances.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 55104-35-3, and how the biochemistry of the body works.Synthetic Route of 55104-35-3

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1515O – PubChem