Category: 5471-63-6

《Generation and Reactivity of a NiIII2(μ-1,2-peroxo) Complex》 was written by Zhao, Norman; Filatov, Alexander S.; Xie, Jiaze; Hill, Ethan A.; Rogachev, Andrey Yu.; Anderson, John S.. HPLC of Formula: 5471-63-6 And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

High-valent transition metal-oxo, -peroxo, and -superoxo complexes are crucial intermediates in both biol. and synthetic oxidation of organic substrates, water oxidation, and oxygen reduction While high-valent oxygenated complexes of Mn, Fe, Co, and Cu are increasingly known, high-valent oxygenated Ni complexes are comparatively rarer. Herein authors report the isolation of such an unusual high-valent species in a thermally unstable NiIII2(μ-1,2-peroxo) complex, which was characterized using single-crystal x-ray diffraction and x-ray absorption, NMR, and UV-visible spectroscopies. Reactivity studies show that this complex is stable toward dissociation of oxygen but reacts with simple nucleophiles and electrophiles.1,3-Diphenylisobenzofuran(cas: 5471-63-6HPLC of Formula: 5471-63-6) was used in this study.

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.HPLC of Formula: 5471-63-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthetic Route of C20H14OIn 2021 ,《Conferring Ti-Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy》 was published in Advanced Materials (Weinheim, Germany). The article was written by Liang, Shuang; Xiao, Xiao; Bai, Lixin; Liu, Bin; Yuan, Meng; Ma, Ping’an; Pang, Maolin; Cheng, Ziyong; Lin, Jun. The article contains the following contents:

The development of highly efficient, multifunctional, and biocompatible sonosensitizer is still a priority for current sonodynamic therapy (SDT). Herein, a defect-rich Ti-based metal-organic framework (MOF) (D-MOF(Ti)) with greatly improved sonosensitizing effect is simply constructed and used for enhanced SDT. Compared with the commonly used sonosensitizer TiO2, D-MOF(Ti) results in a superior reactive oxygen species (ROS) yield under ultrasound (US) irradiation due to its narrow bandgap, which principally improves the US-triggered electron-hole separation Meanwhile, due to the existence of Ti3+ ions, D-MOF(Ti) also exhibits a high level of Fenton-like activity to enable chemodynamic therapy. Particularly, US as the excitation source of SDT can simultaneously enhance the Fenton-like reaction to achieve remarkably synergistic outcomes for oncotherapy. More importantly, D-MOF(Ti) can be degraded and metabolized out of the body after completion of its therapeutic functions without off-target toxicity. Overall, this work identifies a novel Ti-familial sonosensitizer harboring great potential for synergistic sonodynamic and chemodynamic cancer therapy. In the experiment, the researchers used many compounds, for example, 1,3-Diphenylisobenzofuran(cas: 5471-63-6Synthetic Route of C20H14O)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) is a fluorescent dye. 1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.Synthetic Route of C20H14O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

《Photophysical and electrochemical properties of two trans-A2B-corroles: differences between phenyl or pyrenyl groups at the meso-10 position》 was written by Acunha, Thiago V.; Victoria, Henrique F. V.; Krambrock, Klaus; Marques, Amanda C.; Costa, Luiz Antonio S.; Iglesias, Bernardo A.. Quality Control of 1,3-Diphenylisobenzofuran And the article was included in Physical Chemistry Chemical Physics in 2020. The article conveys some information:

The present study reported on the optical and photophys. properties of trans-A2B-corroles possessing pyrenyl units attached at the meso-10-position and compares them with those of model trans-A2B-corroles having Ph substituents at that position. In contrast to the model meso-substituted corrole, the new pyrenyl-corrole showed slightly red-shifted absorption bands and blue-shifted emission, slightly higher fluorescence quantum yield, and more importantly, it showed better photo-stability under white-light illumination. Theor. calculations were used to determine the electronic transitions and geometries of the singlet and triplet excited states (TD-DFT and NTO). Moreover, we demonstrated that the pyrenyl-corrole in analogy to previously studied model corroles was able to generate reactive oxygen species (ROS) under visible light using photo-degradation of 1,3-diphenylisobenzofuran (DBPF), a singlet oxygen quencher, and EPR spectroscopy allied with the spin-trapping method was used for identifying singlet oxygen species. The results showed that the pyrenyl unit attached at the meso-10-position of the corrole increased the photo-stability and efficiency in ROS generation compared to the Ph substituent.1,3-Diphenylisobenzofuran(cas: 5471-63-6Quality Control of 1,3-Diphenylisobenzofuran) was used in this study.

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.Quality Control of 1,3-Diphenylisobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Quality Control of 1,3-DiphenylisobenzofuranIn 2021 ,《A Robust Narrow Bandgap Vanadium Tetrasulfide Sonosensitizer Optimized by Charge Separation Engineering for Enhanced Sonodynamic Cancer Therapy》 was published in Advanced Materials (Weinheim, Germany). The article was written by Liang, Shuang; Liu, Bin; Xiao, Xiao; Yuan, Meng; Yang, Ling; Ma, Ping’an; Cheng, Ziyong; Lin, Jun. The article contains the following contents:

The development and optimization of sonosensitizers for elevating intratumoral reactive oxygen species (ROS) are definitely appealing in current sonodynamic therapy (SDT). Given this, branched vanadium tetrasulfide (VS4) nanodendrites with a narrower bandgap (compared with the most extensively explored sonosensitizers) are presented as a new source of sonosensitizer, which allows a more effortless separation of sono-triggered electron-hole pairs for ROS generation. Specifically, platinum (Pt) nanoparticles and endogenous high levels of glutathione (GSH) are rationally engineered to further optimize its sono-sensitized performance. As cocatalyst, Pt is conducive to trapping electrons, whereas GSH, as a natural hole-scavenger, tends to capture holes. Compared with the pristine VS4 sonosensitizer, the GSH-Pt-VS4 nanocomposite can greatly prolong the lifetime of the charge and confer a highly efficacious ROS production activity. Furthermore, such nanoplatforms are capable of reshaping tumor microenvironments to realize ROS overproduction, contributed by overcoming tumor hypoxia to improve SDT-triggered singlet oxygen production, catalyzing endogenic hydrogen peroxide into destructive hydroxyl radicals for chemodynamic therapy, and depleting GSH to amplify intratumoral oxidative stress. All these combined effects result in a significantly efficient tumor suppression outcome. This study enriches sonosensitizer research and proves that sonosensitizers can be rationally optimized by charge separation engineering strategy. In the part of experimental materials, we found many familiar compounds, such as 1,3-Diphenylisobenzofuran(cas: 5471-63-6Quality Control of 1,3-Diphenylisobenzofuran)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) is a fluorescent dye. 1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.Quality Control of 1,3-Diphenylisobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Related Products of 5471-63-6In 2021 ,《Porous polymers from octa(amino-phenyl)silsesquioxane and metalloporphyrin as peroxidase-mimicking enzyme for malathion colorimetric sensor》 appeared in Colloids and Surfaces, B: Biointerfaces. The author of the article were Guo, Xiaojun; Chen, Mohan; Jing, Lu; Li, Jie; Li, Yanhong; Ding, Rui; Zhang, Xiaomei. The article conveys some information:

Rapid and efficient pesticide detection methods are particularly important due to the growing problems of pesticide residues. Here, a new azo-based porous organic polymer, Azo(Fe)PPOP, was prepared from octa(amino-phenyl)silsesquioxane (OAPS) and iron(III) 5,10,15,20-tetrakis(4-nitrophenyl)porphyrin (FeTPP(NO2)4) via a simple coupling reaction without the participation of metal catalysts. The inorganic cage units of OAPS endowed Azo(Fe)PPOP a porous framework, high surface area, favorably thermal and chem. stability. In Azo(Fe)PPOP, iron(III) porphyrin units were individually isolated in a fixed location, which could effectively avoid dimerization or self-oxidation as happens as in the case of porphyrin monomers. Such a unique structure made Azo(Fe)PPOP exhibit an excellent peroxidase-like catalytic performance in the presence of H2O2 and 3,3′,5,5′-tetramethylbenzidine (TMB). Because of these advantages, we established a selective, facile, and sensitive colorimetric platform for direct detection of malathion within a very short time (3 min) with a low detection limit (8.5 nM). In addition, the recognition mechanism between Azo(Fe)PPOP and malathion was verified using XPS spectra. The practicality of the constructed platform was further executed by the detection of the pesticide in soil and food samples. The experimental process involved the reaction of 1,3-Diphenylisobenzofuran(cas: 5471-63-6Related Products of 5471-63-6)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) is a fluorescent dye. 1,3-Diphenylisobenzofuran is the model compound in studies of singlet fission.Related Products of 5471-63-6

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Loukhina, I. V.; Gradova, M. A.; Khudyaeva, I. S.; Lobanov, A. V.; Belykh, D. V. published their research in Russian Journal of General Chemistry in 2021. The article was titled 《Synthesis and photocatalytic properties of magnesium silicate modified with cationic chlorin e6 derivatives》.Electric Literature of C20H14O The article contains the following contents:

Synthetic samples of layered magnesium silicate modified with mono-, di-, and tricationic chlorin e6 derivatives have exhibited comparable photochem. activity towards a series of reductants: 1,3-diphenylisobenzofuran selectively oxidizable with singlet oxygen and 1,2-phenylenediamine readily oxidizable with hydrogen peroxide. The optimal photochem. activity of the modified magnesium silicates has been achieved at the ratio of 4-8 μmol of chlorin e6 derivative per 1 g of magnesium silicate. In addition to this study using 1,3-Diphenylisobenzofuran, there are many other studies that have used 1,3-Diphenylisobenzofuran(cas: 5471-63-6Electric Literature of C20H14O) was used in this study.

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used to study the single crystal molecular structure and solution photophysical properties of DPBF.Electric Literature of C20H14O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

《Capture and Release of Singlet Oxygen in Coordination-Driven Self-Assembled Organoplatinum(II) Metallacycles》 was published in Journal of the American Chemical Society in 2020. These research results belong to He, Yan-Qin; Fudickar, Werner; Tang, Jian-Hong; Wang, Heng; Li, Xiaopeng; Han, Jun; Wang, Zhengping; Liu, Min; Zhong, Yu-Wu; Linker, Torsten; Stang, Peter J.. COA of Formula: C20H14O The article mentions the following:

Singlet oxygen (1O2), as an important active reagent, has found wide applications in photodynamic therapy (PDT), synthetic chem., and materials science. Organic conjugated aromatics serving as hosts to capture and release singlet oxygen have been systematically investigated over the last decades. Herein, we present a [6 + 6] organoplatinum(II) metallacycle by using ∼180° dipyridylanthracene donor and ∼120° Pt(II) acceptor as the building blocks, which enables the capture and release of singlet oxygen with relatively high photooxygenation and thermolysis rate constants The photooxygenation of the metallacycle to the corresponding endoperoxide was performed by sensitized irradiation, and the resulting endoperoxide is stable at room temperature and can be stored under ambient condition over months. Upon simple heating of the neat endoperoxide under inert atm. at 120°C for 4 h, the resulting endoperoxide can be reconverted to the corresponding parent form and singlet oxygen. The photooxygenation and thermolysis products were characterized by NMR spectroscopy and electrospray ionization time-of-flight mass spectrometric anal. D. functional theory calculations were conducted in order to reveal the frontier MO interactions and reactivity. This work provides a new material platform for singlet oxygen related promising applications. The experimental part of the paper was very detailed, including the reaction process of 1,3-Diphenylisobenzofuran(cas: 5471-63-6COA of Formula: C20H14O)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used to study the single crystal molecular structure and solution photophysical properties of DPBF.COA of Formula: C20H14O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Xia, Xiang; Wang, Ran; Hu, Yingqi; Liu, Wei Jian; Liu, Ting; Sun, Wen; Fan, Jiangli; Peng, Xiaojun published an article in 2021. The article was titled 《A novel photosensitizer for lipid droplet-location photodynamic therapy》, and you may find the article in Frontiers in Chemistry (Lausanne, Switzerland).Safety of 1,3-Diphenylisobenzofuran The information in the text is summarized as follows:

Lipid droplets (LDs), an extremely important cellular organelle, are responsible for the storage of neutral lipids in multiple biol. processes, which could be a potential target site for photodynamic therapy (PDT) of cancer. Herein, a lipid droplet-targeted photosensitizer (BODSeI) is developed, allowing for fluorescence imaging-guided PDT. Owing to the location of lipid droplets, BODSeI demonstrates enhanced PDT efficiency with an extremely low IC50 value (around 125 nM). Besides, BODSeI shows good biocompatibility and high photostability. Therefore, BODSeI is promising for droplet-location PDT, which may trigger wide interest for exploring the pathway of lipid droplet-location PDT. In the experiment, the researchers used many compounds, for example, 1,3-Diphenylisobenzofuran(cas: 5471-63-6Safety of 1,3-Diphenylisobenzofuran)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.Safety of 1,3-Diphenylisobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Madridejos, Jenica Marie L.; Harada, Takaaki; Falcinella, Alexander J.; Small, Thomas D.; Golovko, Vladimir B.; Andersson, Gunther G.; Metha, Gregory F.; Kee, Tak W. published an article in 2021. The article was titled 《Optical Properties of the Atomically Precise C4 Core [Au9(PPh3)8]3+ Cluster Probed by Transient Absorption Spectroscopy and Time-Dependent Density Functional Theory》, and you may find the article in Journal of Physical Chemistry C.Application In Synthesis of 1,3-Diphenylisobenzofuran The information in the text is summarized as follows:

Structural isomerism of [Au9(PPh3)8]3+ has been studied exptl., mostly concerning the symmetry of the Au9 core. Recently, the C4 isomer of [Au9(PPh3)8]3+ has been shown to exist in solution phase while the D2h isomer is present in the solid state [Inorganic Chem.2017, 56, 8319-8325]. In this work, geometric, electronic, and optical properties of C4 [Au9(PPh3)8]3+ are investigated by using the combined second-order d.-functional tight-binding (DFTB2) method and time-dependent d. functional theory (TD-DFT) calculations with spin-orbit coupling. Addnl., the excited-state relaxation dynamics of the [Au9(PPh3)8]3+ cluster in dichloromethane and methanol solutions are studied using femtosecond transient absorption spectroscopy. [Au9(PPh3)8]3+ is optically pumped to different excited states by using 432, 532, and 603 nm light. For all three pump wavelengths, the photoexcitation event induces an excited-state absorption (ESA) band centered at 600 nm with decay time constants of 2.0 and 45 ps, which are attributed to intersystem crossing and nonradiative relaxation of [Au9(PPh3)8]3+, resp. On the other hand, optical pumping of [Au9(PPh3)8]3+ using 432 nm light gives rise to an addnl. ESA band at 900 nm. This band exhibits fast relaxation through internal conversion with a time constant of ~0.3 ps. Our combined computational and exptl. study reveals that the excitation wavelength-dependent relaxation dynamics of the [Au9(PPh3)8]3+ cluster are related to the different electron densities of the excited states of [Au9(PPh3)8]3+, consistent with it possessing mol.-like electronic states. After reading the article, we found that the author used 1,3-Diphenylisobenzofuran(cas: 5471-63-6Application In Synthesis of 1,3-Diphenylisobenzofuran)

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used as quencher during the photoinactivation of TA-3 mouse mammary carcinoma cells containing hematoporphyrin.Application In Synthesis of 1,3-Diphenylisobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

《Photocatalytic degradation of tetracycline by a novel (CMC)/MIL-101(Fe)/β-CDP composite hydrogel》 was published in Frontiers in Chemistry (Lausanne, Switzerland) in 2020. These research results belong to Zhang, Hui; Zhou, Liang; Li, Jing; Rong, Sijia; Jiang, Jianping; Liu, Shengquan. Computed Properties of C20H14O The article mentions the following:

Herein, we report a novel CM-cellulose (CMC)/MIL-101 (Fe)/poly(β-cyclodextrin) (β-CDP) hydrogel with high photocatalytic activity. β-CDP can significantly enhance the photoactivity of MIL-101(Fe) in the hydrogel prepared by a simple solvothermal method. The structure and property of this composite hydrogel were characterized by Fourier transform IR spectroscopy, X-ray diffraction, SEM, and transmission electron microscopy. Tetracycline was selected as a model pharmaceutical antibiotic to evaluate the photocatalytic activity of the composite hydrogel under visible light irradiation and darkness, resp. This composite hydrogel shows excellent activity for degrading pharmaceutical antibiotics under visible light irradiation The increased photocatalytic activity can be attributed to β -CDP, which acts as a promoter and affords an efficient separation of photogenerated electron-hole pairs of MIL-101(Fe). Moreover, the composite hydrogel is shown to have good water retainability. The hydrogel is inexpensive and shows high photocatalytic activity. Hence, it can be used as an efficient photocatalytic material.1,3-Diphenylisobenzofuran(cas: 5471-63-6Computed Properties of C20H14O) was used in this study.

1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used to study the single crystal molecular structure and solution photophysical properties of DPBF.Computed Properties of C20H14O

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem