Category: 54109-03-4

Reference of 54109-03-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 54109-03-4, 5-Chloroisobenzofuran-1(3H)-one, introducing its new discovery.

Color tuning of cyclometalated iridium complexes through modification of phenylpyrazole derivatives and ancillary ligand based on ab initio calculations

Various iridium complexes consisting of phenylpyrazole (ppz) ligands and isoquinolinecarboxylic acids (iq) as ancillary ligands were designed by energy band-gap calculations via ab initio calculations and synthesized to give rise to various emission wavelengths as expected. Fine color tuning was achieved through varying the position of the methyl substituent on the phenylpyrazole moiety with HOMO electron densities. Additional color tuning was made possible by altering the LUMO through the use of different ancillary ligands such as 1-isoquinolinecarboxylic acid (liq) and 3-isoquinolinecarboxylic acid (3iq).

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 54109-03-4. In my other articles, you can also check out more blogs about 54109-03-4

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2622O – PubChem

Application of 54109-03-4, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.54109-03-4, Name is 5-Chloroisobenzofuran-1(3H)-one, molecular formula is C8H5ClO2. In a article£¬once mentioned of 54109-03-4

N-Arylation of heterocycles promoted by tetraethylenepentamine in water

Tetraethylenepentamine and triethylenetetramine are found to be efficient organic bases for the N-arylation of pyrazole and imidazole with aryl and heteroaryl-iodides and -bromides catalyzed by CuI in water at moderate temperature. The cross-couplings proceed smoothly with good to excellent yields and a variety of functional groups are tolerated under this condition.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 54109-03-4

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2646O – PubChem

54109-03-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.54109-03-4, Name is 5-Chloroisobenzofuran-1(3H)-one, molecular formula is C8H5ClO2. In a Article, authors is Sen, Malay£¬once mentioned of 54109-03-4

Dehydrative Cp?Co(III)-Catalyzed C-H Bond Allenylation

An efficient, unprecedented reactivity of Cp?Co(III) for the synthesis of tetrasubstituted allenes under mild conditions is disclosed. Electron-rich and highly nucleophilic cobalt facilitates the dehydrative C-H bond allenylation directly from propargylic alcohols without any derivatization. The reaction proceeds via reversible cyclometalation followed by alcohol-directed regioselective alkyne insertion and beta-hydroxy elimination to provide the tetrasubstituted allenes.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 54109-03-4

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2636O – PubChem

54109-03-4, 5-Chloroisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

54109-03-4, Example 5 Under a nitrogen atmosphere, a mixture of NiCl2 (0.2 g, 0.0015 mol) and triphenylphosphine (1.6 g, 0.0061 mol) in acetonitrile (80 ml)was heated at reflux for 45 minutes. After cooling to room temperature, zinic powder was added (0.39 g, 0.006 mol) at stirred for 15 minutes before a solution of 5-chloro-3H-isobenzofuran-1-one (3.4 g, 0.02 mol) in THF (40 mL) was added. After stirring for a further 10 minutes, NaCN (1.1 g, 0.021 mol) was added and the reaction heated at 70¡ã C. for 3 hrs, cooled, diluted with acetonitrile (50 mL), and then filtered through celite. The filtrate was concentrated under reduced pressure and the residue was refluxed in water (150 mL) for 10 minutes and allowed to cool to room temperature. Filtration and followed by drying in vacuo give the crude 5-cyano-3H-isobenzofuran-1-one (2.5 g).

As the paragraph descriping shows that 54109-03-4 is playing an increasingly important role.

Reference£º
Patent; H. Lundbeck A/S; US2002/198391; (2002); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.54109-03-4,5-Chloroisobenzofuran-1(3H)-one,as a common compound, the synthetic route is as follows.,54109-03-4

a) 5-Chloro-1,3-dihydro-2-benzofuran-1-ol To a solution of 5-chlorophthalide (3.64 g, 21.6 mmol) in dichloromethane (100 mL) at -78¡ã C. was added di-isobutylaluminium hydride (1M in toluene) (23.8 mL, 23.8 mmol) dropwise. After 1 h the reaction mixture was quenched with a saturated solution of sodium tartrate (250 mL), allowed to warm to room temperature and stirred for 1h. The layers were separated and the aqueous layer extracted with dichloromethane. The combined organic layers were dried (MgSO4), filtered and concentrated in vacuo to yield the title compound as a white solid.

The synthetic route of 54109-03-4 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Agejas-Chicharro, Javier; Belen Bueno Melendo, Ana; Camp, Nicholas Paul; Gilmore, Jeremy; Jimenez-Aguado, Alma Maria; Lamas-Peteira, Carlos; Marcos-Llorente, Alicia; Mazanetz, Michael Philip; Montero Salgado, Carlos; Timms, Graham Henry; Williams, Andrew Caerwyn; US2004/122001; (2004); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem