Category: 50551-63-8

Bianco, Armandodoriano published the artcileNew insights on the reaction of benzofurans with aromatic aldehydes. Synthesis of new triphenylmethane-type dyes, Product Details of C9H8O2, the main research area is triphenylmethane dye preparation benzofuran aromatic aldehyde; pH indicator preparation benzofuran aromatic aldehyde; benzofuran coupling aromatic aldehyde dye synthesis.

New mols. with a triphenylmethane-type structure have been synthesized based on the structure of colored compounds obtained from natural substrates. Satisfactory yields were obtained from benzofuran derivatives as starting material, which have been condensed in methanol with aromatic aldehydes in the presence of catalytic amounts of mineral acids. Several of the new compounds behave as pH indicators. The condensation products, obtained from suitably functionalized starting products, can be easily oxidized giving rise to new triphenylmethane-type dyes, such as I.

Gazzetta Chimica Italiana published new progress about Acid-base indicators. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Product Details of C9H8O2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Mann, Inderjit S. published the artcileTransition metal-directed synthesis of moracin M, a phytoalexin of Morus alba Linn, Formula: C9H8O2, the main research area is moracin M; resorcinylbenzofuran; benzofuran resorcinyl; coupling stannylbenzofuran bromozincbenzofuran iodoresorcinol; iodoresorcinoltricarbonylchromium coupling halobenzofuran.

2-(5-Resorcinyl)benzofurans have been synthesized by the Pd-catalyzed cross-coupling of 2-trimethylstannyl- or 2-bromozincbenzofurans with functionalized 5-iodoresorcinols. These were synthesized by the triisopropylsilyloxy-directed remote (C-5) lithiation/iodination of the O,O-bis(triisopropylsilyl)resorcinoltricarbonylchrhomium(0) complex. The method was applied to the synthesis of moracin M (I).

Tetrahedron published new progress about Coupling reaction. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Formula: C9H8O2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Mann, Inderjit S. published the artcileTransition metal-mediated synthesis of some prenylated phytoalexins of Morus alba Linn, Category: benzofurans, the main research area is moracin prenylated; resorcinylbenzofuran; benzofuran resorcinyl; coupling stannylbenzofuran iodoresorcinol chromium carbonyl.

Directed functionalization of resorcinol and benzofuran rings was achieved by activation with a coordinated tricarbonylchromium(0) unit and vicinal or remote lithiation directed by methoxy or tert-butyldiphenylsilyloxy groups resp. The process was applied either before [to the geranylbenzofuran for mulberrofuran B (I, R = Me, R1 = geranyl, R2-R4 = H)] or after [for moracin C (I, R-R2 = H, R3 = prenyl, R4 = Me)] Pd-catalyzed coupling of the 2-stannylated benzofuran and the 5-iodinated resorcinol moieties. In addition moracin I (I, R, R1, R3 = H, R2 = prenyl, R4 = Me) was synthesized by a Stille coupling of the stannylated benzofuran with the phloroglucinol triflate. Application to the synthesis of albafuran A (I, R, R1, R3, R4 = H, R2 = geranyl) gave, unexpectedly, the 3-geranylbenzofuran II.

Tetrahedron published new progress about Coupling reaction. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Clough, John M. published the artcileTransition metal-mediated organic synthesis: synthesis of moracin M, Category: benzofurans, the main research area is halobenzofuran metalloresorcinol chromium carbonyl coupling; metallobenzofuran haloresorcinol chromium carbonyl coupling; coupling benzofuran resorcinol palladium catalyst; moracin M.

The Pd-catalyzed cross-coupling of 2-halo- or 2-metallobenzofurans with both 5-metallo- or 5-haloresorcinol tricarbonyl chromium(0) complexes or with the uncomplexed resorcinols, has been evaluated and in consequence, moracin M (I) has been synthesized in good yield by the cross-coupling of 6-(tert-butyldiphenylsiloxy)-2-trimethylstannylbenzofuran with 5-iodoresorcinol bis(triisopropylsilyl) ether and fluoride ion deprotection of the product.

Tetrahedron Letters published new progress about Coupling reaction. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Nath, Sarbasri published the artcileFast Synthesis of Benzofurans from Coumarins, Application In Synthesis of 50551-63-8, the main research area is coumarin zinc oxide catalyst microwave irradiation ring contraction; benzofuran preparation green chem.

A new solid support, Zinc oxide was used as a green catalyst for the ring contraction of coumarins to benzofurans. Employing microwave induced synthesis whenever possible, minimizing the use of toxic solvents. Benzofurans was achieved from coumarins by ring contraction reaction in single step. Microwave irradiation was used to shorten the reaction time and to improve the yield.

Journal of Ultra Chemistry published new progress about Benzofurans Role: SPN (Synthetic Preparation), PREP (Preparation). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Application In Synthesis of 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Graham, Samuel L. published the artcileTopically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides, HPLC of Formula: 50551-63-8, the main research area is benzofuransulfonamide preparation carbonic anhydrase inhibition; indolesulfonamide preparation carbonic anhydrase inhibition; carbonic anhydrase inhibition benzofuransulfonamide indolesulfonamide; ocular hypotensive benzofuransulfonamide indolesulfonamide; glaucoma treatment indolesulfonamide benzofuransulfonamide.

Derivatives of 2-benzofuran- and 2-indolesulfonamide (e.g., I, II) were prepared for evaluation as topically active ocular hypotensive agents. These compounds were excellent inhibitors of carbonic anhydrase and lowered intraocular pressure in a rabbit model of ocular hypertension. However, their development for clin. use was precluded because they cause dermal sensitization in guinea pigs. A correlation between electrophilicity, as assessed by in vitro reactivity with reduced glutathione, and dermal sensitization potential was further documented.

Journal of Medicinal Chemistry published new progress about Allergens Role: RCT (Reactant), RACT (Reactant or Reagent). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, HPLC of Formula: 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Fang, Huaquan published the artcileA Pincer Ruthenium Complex for Regioselective C-H Silylation of Heteroarenes, Quality Control of 50551-63-8, the main research area is pincer ruthenium complex catalyst regioselective silylation heteroarene; heteroaryl silane preparation regioselective Hiyama Denmark coupling iodobenzene.

A pincer Ru(II) catalyst for the highly efficient undirected silylation of O- and S-heteroarenes with (TMSO)2MeSiH and Et3SiH is described, producing heteroarylsilanes with exclusive C2-regioselectivity, good functional-group tolerance, and high turnover numbers (up to 1960). The synthetic utility of the silylated products is demonstrated by Pd-catalyzed Hiyama-Denmark cross-coupling under mild conditions. One-pot, two-step silylation and coupling procedures have been also developed.

Organic Letters published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Quality Control of 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Zhang, Bang-Le published the artcileA new efficient method for the total synthesis of linear furocoumarins, Product Details of C9H8O2, the main research area is furocoumarin total synthesis; psoralen total synthesis; benzofuran preparation; nitroalkyl phenol Nef oxidation intramol cyclocondensation.

A new efficient method for the synthesis of linear furocoumarins by a Nef reaction and intramol. cyclocondensation in one pot results in the construction of a benzofuran ring. This method provides a new strategy to furnish the benzofuran framework easily, and also allows the convenient synthesis of furocoumarin derivatives with different substituents on the coumarin ring by a subsequent Pechmann reaction. This strategy has also been applied to the preparation of four addnl. benzofuran derivatives

Synlett published new progress about Coumarins Role: SPN (Synthetic Preparation), PREP (Preparation). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Product Details of C9H8O2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Sun, Nan published the artcileZeolite-catalyzed synthesis of 2,3-unsubstituted benzo[b]furans via the intramolecular cyclization of 2-aryloxyacetaldehyde acetals, Synthetic Route of 50551-63-8, the main research area is benzofuran preparation tin exchanged zeolite catalyst cyclization aryloxyacetaldehyde acetal.

An efficient and environmentally benign heterogeneous catalytic process for the synthesis of 2,3-unsubstituted benzo[b]furans was established via the intramol. cyclization of 2-aryloxyacetaldehyde acetals. By using tin-exchanged H-β zeolite (Sn-β) as catalyst, a wide range of functionalized 2,3-unsubstituted benzo[b]furans could be prepared in good to excellent yields. The Sn-β zeolite catalyst also exhibited excellent shape selectivity on the cyclization of meta-substituted 2-aryloxyacetaldehyde acetals, and 6-substituted isomers were preferably formed up to 97% regio-selectivity. Moreover, Sn-β zeolite could be easily recovered and reused without any noticeable activity loss.

Tetrahedron published new progress about Beta zeolites Role: CAT (Catalyst Use), USES (Uses) (tin-exchanged). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Synthetic Route of 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Ross, Rachel J. published the artcileRhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening, Related Products of benzofurans, the main research area is rhodium catalyzed diastereoselective intermol cyclopropanation; benzofuran indole alkene cyclopropene ring opening.

The generation of metal carbenoids via ring opening of cyclopropenes by transition metals offers a simple entry into highly reactive intermediates. Herein, we describe a diastereoselective intermol. rhodium-catalyzed cyclopropanation of heterocycles and alkenes using cyclopropenes as carbene precursors with a low loading of a com. available rhodium catalyst. The reported method is scalable and could be performed with catalyst loadings as low as 0.2 mol %, with no impact to the reaction yield or selectivity.

Organic Letters published new progress about Crystal structure. 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, Related Products of benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem