Category: 39581-55-0

39581-55-0, Name is 5-Methoxybenzofuran-3(2H)-one, belongs to benzofuran compound, is a common compound. Computed Properties of C9H8O3In an article, once mentioned the new application about 39581-55-0.

A novel tetradium alkali derivatives, their preparation and use (by machine translation)

The invention relates to the field of pharmaceutical chemistry, and in particular relates to a novel class of tetradium alkali derivatives. The invention also discloses a method for preparing these derivatives and their use in the treatment of tumor diseases. (by machine translation)

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Benzofuran – Wikipedia,
Benzofuran | C8H2224O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 5-Methoxybenzofuran-3(2H)-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 39581-55-0, Name is 5-Methoxybenzofuran-3(2H)-one, molecular formula is C9H8O3

OPIOID RECEPTOR MODULATORS

The present invention provides a compound having the structure wherein A is a ring structure, with or without substitution; X1 is C or N; X2 is N, 0, or S; Y1 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 2 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y3 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 4 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y5 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); a and P are each present or absent and when present each is a bond.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Quality Control of 5-Methoxybenzofuran-3(2H)-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 39581-55-0, in my other articles.

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2221O – PubChem

39581-55-0, Name is 5-Methoxybenzofuran-3(2H)-one, belongs to benzofuran compound, is a common compound. Application In Synthesis of 5-Methoxybenzofuran-3(2H)-oneIn an article, once mentioned the new application about 39581-55-0.

Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties

A virtual screening campaign aimed at finding structurally new compounds active at 5-HT6R provided a set of candidates. Among those, one structure, 4-(5-{[(2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}ethyl)amino]methyl}furan-2-yl)phenol (1, 5-HT6R Ki = 91 nM), was selected as a hit for further optimization. As expected, the chemical scaffold of selected compound was significantly different from all the serotonin receptor ligands published to date. Synthetic efforts, supported by molecular modelling, provided 43 compounds representing different substitution patterns. The derivative 42, 4-(5-{[(2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}ethyl)amino]methyl}furan-2-yl)phenol (5-HT6R Ki = 25, 5-HT2AR Ki = 32 nM), was selected as a lead and showed a good brain/plasma concentration profile, and it reversed phencyclidine-induced memory impairment. Considering the unique activity profile, the obtained series might be a good starting point for the development of a novel antipsychotic or antidepressant with pro-cognitive properties.

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Benzofuran – Wikipedia,
Benzofuran | C8H2244O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Quality Control of 5-Methoxybenzofuran-3(2H)-one, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 39581-55-0, name is 5-Methoxybenzofuran-3(2H)-one. In an article£¬Which mentioned a new discovery about 39581-55-0

New fluoride-promoted hypoiodite-catalytic oxidative cycloetherification to aromatic spiroketals

A new catalytic application of hypoiodite reagents generated in situ from iodide ions is found, which succeeded in the synthesis of bisbenzannelated spiroketal cores for the first time. Fluoride was proven to be obligatory for this spiroketalization, which is the first fluoride-promoted oxidative cycloetherification to aromatic spiroketals.

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Benzofuran – Wikipedia,
Benzofuran | C8H2249O – PubChem

Application of 39581-55-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 39581-55-0, 5-Methoxybenzofuran-3(2H)-one, introducing its new discovery.

Benzofuran Bioisosteres of Hallucinogenic Tryptamines

The benzofuran analogues of the hallucinogens 5-methoxy-N,N-dimethyltryptamine and 5-methoxy-alpha-methyltryptamine were synthesized and evaluated for affinity at the serotonin 5-HT2 and 5-HT1A receptors in rat brain homogenate, labeled with <125I>-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (<125I>DOI) and <3H>-8-hydroxy-2-(N,N-di-n-propylamino)tetralin (<3H>-8-OH-DPAT), respectively.At the 5-HT2 receptor, the benzofurans had slightly decreased affinities, approximately one-third and one-sixth those of the indoles, for the primary amines and the tertiary amines, respectively.The benzofurans also had lower affinity at the 5-HT1A receptor, but decreased only about 20-30percent from that of the indole isosteres.Thus, the 5-HT1A receptor is less discriminating with respect to preference for an indole versus a benzofuran, although all of the compounds did have higher affinities for the 5-HT2 receptor than for the 5-HT1A receptor.It is suggested that benzofurans may be useful in the design of serotonin receptor ligands.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 39581-55-0. In my other articles, you can also check out more blogs about 39581-55-0

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Benzofuran – Wikipedia,
Benzofuran | C8H2245O – PubChem

Application of 39581-55-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.39581-55-0, Name is 5-Methoxybenzofuran-3(2H)-one, molecular formula is C9H8O3. In a article£¬once mentioned of 39581-55-0

NOVEL TRICYCLIC CALCIUM SENSING RECEPTOR ANTAGONISTS FOR THE TREATMENT OF OSTEOPOROSIS

Novel tricyclic compounds of the formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing osteoporosis and similar conditions. The compounds are effective as calcium sensing receptor antagonists. Pharmaceutical compositions and methods of treatment are also included.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 39581-55-0

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2223O – PubChem