Category: 28241-99-8

Synthesis and pharmacological activity of benzofurylhydroxyureas and benzofurylhydroxamic acids was written by Onuchina, O. A.;Zaitsev, S. A.;Arzamastsev, A. P.;Kalinkina, M. A.;Granik, V. G.. And the article was included in Pharmaceutical Chemistry Journal in 2006.Computed Properties of C11H10O3 This article mentions the following:

A series of benzofuran derivatives of hydroxyurea, e.g. I (R = NH₂), and hydroxamic acid, e.g. I (R = Me), has been obtained. Hydroxyureas have been O-alkylated with 3-bromomethyl-4-methylfuroxane. The antiinflammatory and antiulcer properties of these compounds have been investigated. In the experiment, the researchers used many compounds, for example, 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8Computed Properties of C11H10O3).

1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Computed Properties of C11H10O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Synthesis of 5-hydroxy-N-(2-vinyloxyalkyl)indoles from dicarbonyl compounds and vinyloxyalkylamines was written by Kukharev, B. F.;Stankevich, V. K.;Klimenko, G. R.;Lobanova, N. A.. And the article was included in Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya) in 1997.Formula: C11H10O3 This article mentions the following:

N-(Vinyloxyalkyl) enamino ketones were obtained by the condensation of vinyloxyalkylamines with acetylacetone or Et acetoacetate. Their subsequent reactions with 1,4-benzoquinone produce the corresponding 5-hydroxy-2-methyl-N-(2-vinyloxyalkyl)indoles in 17-43% yields. The structures of the compounds obtained were confirmed by IR and ¹H NMR spectroscopy. In the experiment, the researchers used many compounds, for example, 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8Formula: C11H10O3).

1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Formula: C11H10O3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Effects of solvent on the direction of the Nenitzescu reaction was written by Mukhanova, T. I.;Alekseyeva, L. M.;Kuleshova, Ye. F.;Sheinker, Yu. N.;Granik, V. G.. And the article was included in Khimiko-Farmatsevticheskii Zhurnal in 1993.Quality Control of 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone This article mentions the following:

Nenitzescu heterocyclization reaction of enamino ketones RNHCMe:CHAc (R = H, Me, Ph, 4-MeOC₆H₄) with p-benzoquinone in AcOH afforded benzofuran I in up to 62% yield, whereas indoles II were obtained in MeNO₂ (up to 53% yield). Similar results obtained for RNHCMe:CHBz (R = e.g., H, Me, Ph, benzyl). The mechanism was discussed. In the experiment, the researchers used many compounds, for example, 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8Quality Control of 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone).

1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone (cas: 28241-99-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Quality Control of 1-(5-Hydroxy-2-methylbenzofuran-3-yl)ethanone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem