Category: 13391-27-0

Anderson, Wayne K. published the artcileUse of 2,3-dichloropropene and 1,3-dichlorobut-2-ene as synthons for heterocyclic compounds. Synthesis of 2-methylbenzo[b]furans, 2-methylbenzo[b]thiophenes, and 4-methyl-2H-chromene, Category: benzofurans, the main research area is phenol condensation chloro alkene; thiophenol condensation chloro alkene; cyclization propene arylthio chloro; Claisen rearrangement aryloxychloropropene; benzofuran methyl; benzothiophene methyl; chromene methyl.

Addnl. data considered in indexing and abstracting are available from a source cited in the original document. The ethers I (X = O, R = H, p-Me, p-OMe, p-Cl, o-Me, o-OMe, o-Cl), prepared by condensation of the appropriate phenol with CH2:CClCH2Cl (II), underwent Claisen rearrangement to give the phenols III, acid-catalyzed cyclization of which gave 28-77% benzofurans IV (X = O). The thio ether I (X = S, R = H, p-Me, p-OMe, p-Cl, o-Me), similarly prepared from the appropriate thiophenol and II, cyclized directly on heating in PhNEt2 to give 54-80% benzothiophenes IV (X = S). Condensation of PhOH with MeCCl:CHCH2Cl gave 78% 3-chloro-1-phenoxybut-2-ene, which thermally cyclized to give 64% 4-methyl-2H-chromene.

Journal of the Chemical Society, Perkin Transactions 2: Organic and Bio-Organic Chemistry published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Velasco-Negueruela, A. published the artcileAnalysis by gas chromatography-mass spectrometry of the essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species to the Canary Islands, Spain, Application of 5-Methoxy-2-methylbenzofuran, the main research area is terpene arylpropanoid essential oil Pimpinella GC MS.

The essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species growing in Tenerife, Canary Islands, Spain, were studied by gas chromatog. and gas chromatog.-mass spectrometry. The major components of the flowering tops (flowers + unripe fruits) of P. rupicola (PRFT) were found to be β-bisabolene (34.8%), limonene (10.9%) and α-zingiberene (10.5%), whereas in the flowering tops of P. anagodendron (PAFT), the main constituents were α-zingiberene (32.9%), β-bisabolene (17.9%), β-pinene (15.8%) and ar-curcumene (11.5%). The major compounds found in the stems + leaves of P. rupicola (PRSL) were β-bisabolene (31.6%), α-zingiberene (11.4%) and limonene (10.8%), whereas those of P. anagodendron (PASL) were α-zingiberene (32.3%), β-bisabolene (14.0%) and ar-curcumene (12.6%). In all the oils were found the characteristic constituents of genus Pimpinella, the pseudoisoeugenol esters. In accordance with the morphol., chorol. and chem. differences between both species, we suggest that P. rupicola Svent. is a good taxon and not a synonym of P. anagodendron.

Journal of Chromatography A published new progress about Gas chromatography-mass spectrometry. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Application of 5-Methoxy-2-methylbenzofuran.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Henry, Martyn C. published the artcileSynthesis of Benzo[b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis, Category: benzofurans, the main research area is benzofuran preparation regioselective; aryl alkyl ketone halogenation arylation iron copper catalyst.

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogs, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Organic Letters published new progress about Acetamides Role: RCT (Reactant), RACT (Reactant or Reagent). 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Tabanca, Nurhayat published the artcileGas chromatographic-mass spectrometric analysis of essential oils from Pimpinella aurea, Pimpinella corymbosa, Pimpinella peregrina and Pimpinella puberula gathered from Eastern and Southern Turkey, Application In Synthesis of 13391-27-0, the main research area is Pimpinella essential oil terpene phenylpropanoid.

Essential oils from fruits, stems and leaves and roots of Pimpinella aurea DC., P. corymbosa Boiss., P. peregrina L. were analyzed by gas chromatog. (GC) and gas chromatog.-mass spectrometry (GC-MS) techniques. Fruits and aerial parts of P. puberula (DC.) Boiss were also evaluated. A total of 140 different compounds were identified, and significant qual. and quant. differences were observed among the samples. In fact, the main constituents of each species were different and only the oils extracted from roots shared the same principal compound, epoxy pseudoisoeugenyl-2-Me butyrate (26.8-42.8%). The other fractions were dominated by different sesquiterpene compounds although in three of them, P. aurea stem and leaves, P. puberula fruits and P. puberula stems and leaves, monoterpene constituents also appear as main ones.

Journal of Chromatography A published new progress about Gas chromatography. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Application In Synthesis of 13391-27-0.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Moock, Daniel published the artcileEnantio- and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis, Category: benzofurans, the main research area is octahydrobenzofuran enantioselective preparation; benzofuran preparation enantioselective hydrogenation cascade catalyst; benzofuran; cascade catalysis; enantioselective hydrogenation; heterogeneous catalysis; homogeneous catalysis.

We report an enantio- and diastereoselective, complete hydrogenation of multiply substituted benzofurans in a one-pot cascade catalysis. The developed protocol facilitates the controlled installation of up to six new defined stereocenters and produces architecturally complex octahydrobenzofurans, prevalent in many bioactive mols. A unique match of a chiral homogeneous ruthenium-N-heterocyclic carbene complex and an in situ activated rhodium catalyst from a complex precursor act in sequence to enable the presented process.

Angewandte Chemie, International Edition published new progress about Diastereoselective synthesis. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Salom-Roig, Xavier J. published the artcilePreparation of substituted hydroquinones and benzofurans from 1,4-quinone monoketals, Related Products of benzofurans, the main research area is hydroquinone preparation; propargylhydroquinone preparation dienone phenol type rearrangement; benzofuran preparation; quinone ketal organometallic addition.

An easy procedure for the preparation of 2-substituted hydroquinones, by addition of organolithium or organomagnesium compounds to 1,4-quinone monoketals followed by acid-catalyzed dienone-phenol type rearrangement, is described. Transformation of the propargylated derivatives to benzofurans is also reported.

Synthesis published new progress about Ketals Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Related Products of benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Zhou, Lixin published the artcilePd-catalyzed intramolecular Heck reaction for the synthesis of 2-methylbenzofurans, COA of Formula: C10H10O2, the main research area is methylbenzofuran preparation; iodobenzene aryl bromide intramol Heck reaction palladium catalyst.

A new strategy for the synthesis of 2-methylbenzofurans I (R1 = H, 7-Me, 5-Cl, etc.; R2 = H, Me, COOEt) via the intramol. Heck reaction has been developed. This efficient palladium-catalyzed system showed good catalytic activity. Various substituted 2-methylbenzofurans could be afforded in good to excellent yields.

Tetrahedron Letters published new progress about Aryl iodides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, COA of Formula: C10H10O2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Shen, Yu-Dong published the artcileNatural tanshinone-like heterocyclic-fused ortho-quinones from regioselective Diels-Alder reaction: Synthesis and cytotoxicity evaluation, Computed Properties of 13391-27-0, the main research area is tanshinone analog heterocyclic fused ortho quinone preparation cytotoxicity; benzofuranol regioselective Diels Alder reaction dieneamide aminodiene; structure activity relationship tanshinone analog cytotoxicity.

A series of new natural tanshinone-like oxoheterocyclic-fused ortho-quinone derivatives I [R1 = Me, H; R2 = Ar, H; R3 = H, amide group; R4 = R5 = Me, H] were synthesized from readily available benzofuranol and N-substituted dienes via IBX oxidation-cycloaddition-aromatization procedure. The regiospecific Diels-Alder cycloaddition reactions of N-dienes were achieved efficiently with a variety of dienophiles. It is found that the amide moiety in the mol. could be preserved or eliminated by control of the aromatization conditions. Selected oxoheterocyclic-fused ortho-quinones as well as several thioheterocyclic-fused ortho-quinones we obtained before were evaluated for their cytotoxicities on different cancer cell lines and the Structure-Activity Relationship (SAR) was discussed.

European Journal of Medicinal Chemistry published new progress about Antitumor agents. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Computed Properties of 13391-27-0.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Velasco-Negueruela, A. published the artcileAnalysis by gas chromatography-mass spectrometry of the essential oil from the aerial parts of Pimpinella junoniae Ceb. & Ort., gathered in La Gomera, Canary Islands, Spain, Quality Control of 13391-27-0, the main research area is terpene arylpropanoid gas chromatog oil Pimpinella.

The essential oil from the aerial parts of Pimpinella junoniae Ceb.& Ort., growing in La Gomera, Canary Islands, Spain, was studied by gas chromatog. and gas chromatog.-mass spectrometry, and 43 constituents were identified. The major components were found to be α-zingiberene (20.6%), α-pinene (17.9%), (E)-β-farnesene (9.3%), ar-curcumene (7.4%), β-phellandrene (7.0%), β-bisabolene (6.1%) and epoxypseudoisoeugenyl 2-methylbutyrate (6.0%). The decomposition product of epoxypseudoisoeugenol derivatives, 5-methoxy-2-methylbenzofuran (5.7%), moderate amounts of other arylpropanoids with the pseudoisoeugenol skeleton (total percentage, 5.2%) and other compounds such as β-sesquiphellandrene (3.0%), cis-β-guaiene (1.5%), α-phellandrene (1.5%) and α-bisabolol (1.3%), were also found.

Journal of Chromatography A published new progress about Gas chromatography-mass spectrometry. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Quality Control of 13391-27-0.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem