Moock, Daniel published the artcileEnantio- and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis, Category: benzofurans, the main research area is octahydrobenzofuran enantioselective preparation; benzofuran preparation enantioselective hydrogenation cascade catalyst; benzofuran; cascade catalysis; enantioselective hydrogenation; heterogeneous catalysis; homogeneous catalysis.
We report an enantio- and diastereoselective, complete hydrogenation of multiply substituted benzofurans in a one-pot cascade catalysis. The developed protocol facilitates the controlled installation of up to six new defined stereocenters and produces architecturally complex octahydrobenzofurans, prevalent in many bioactive mols. A unique match of a chiral homogeneous ruthenium-N-heterocyclic carbene complex and an in situ activated rhodium catalyst from a complex precursor act in sequence to enable the presented process.
Angewandte Chemie, International Edition published new progress about Diastereoselective synthesis. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Category: benzofurans.
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem