Category: 1280665-55-5

Electric Literature of 1280665-55-5, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1280665-55-5, molcular formula is C10H11NO3, introducing its new discovery.

The invention discloses a preparation method of Plk (Polo-like kinase) inhibitor drug intermediate 7-amino-2,3-dihydrobenzofuran-4-formic acid (I), which comprises the following steps: by using 3-hydroxy-4-nitrobenzoic acid as a starting material, firstly esterifying, then condensing the starting material with 2-halogeno acetaldehyde or 2-halogeno acetal under the effect of an alkali acid-binding agent to realize alkylation of hydroxyl, then performing Friedel-Crafts reaction under the catalysis of protonic acid or Lewis acid, performing cyclization to obtain 7-nitrobenzofuran-4-methyl formate, and finally performing catalytic and hydride reduction and hydrolysis to obtain high-yield 7-amino-2,3-dihydrobenzofuran-4-formic acid (I). According to the invention, the synthetic route is simplified and optimized, the reaction processes are reduced, the technology is simplified, the cost is lowered and the production yield is high, and the 7-amino-2,3-dihydrobenzofuran-4-formic acid can be produced in large scale to meet the usage requirements, and is suitable for industrial production.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1280665-55-5 is helpful to your research. Electric Literature of 1280665-55-5

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3119O – PubChem

Related Products of 1280665-55-5, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.1280665-55-5, Name is Methyl 7-amino-2,3-dihydrobenzofuran-4-carboxylate, molecular formula is C10H11NO3. In a article，once mentioned of 1280665-55-5

The invention relates to azabicyclo [3.2.1] octane derivatives, their preparation and their use in medicine. Specifically, the invention relates to a compound of general formula (I) indicated by the azabicyclo [3.2.1] octane derivatives, preparation method thereof and its pharmaceutically acceptable salts, and their use as therapeutic agents, in particular the use of the FXR agonists, of formula (I) in the definition of each substituent as defined in the specification. (by machine translation)

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1280665-55-5

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3120O – PubChem

Application of 1280665-55-5, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 1280665-55-5, molcular formula is C10H11NO3, introducing its new discovery.

Dihydroperidinone derivatives, preparation process and pharmaceutical use thereof are disclosed. Specially, new dihydroperidinone derivatives represented by general formula (I), wherein each substituent of the general formula (I) is defined as in the description, their preparation process, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors are disclosed.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1280665-55-5 is helpful to your research. Application of 1280665-55-5

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3122O – PubChem