Awesome Chemistry Experiments For 3-Methylbenzofuran-2-carboxylic acid

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 24673-56-1

Related Products of 24673-56-1, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.24673-56-1, Name is 3-Methylbenzofuran-2-carboxylic acid, molecular formula is C10H8O3. In a article,once mentioned of 24673-56-1

The dianionic species, lithium 2-lithiobenzofuran-3-carboxylate (5) and lithium 3-lithiobenzofuran-2-carboxylate (11b) can be readily generated from the parent acids by reaction with lithium diisopropylamide in tetrahydrofuran at low temperatures.While compound (5) is a useful synthetic intermediate, which reacts efficiently with a number of electrophiles, (11b) instead undergoes rapid opening of the furan ring to give (2-hydroxyphenyl)propynoic acid (10a).By contrast, 5- and 7-methoxybenzofuran-2-carboxylic acids (13a) and (13c) give rise to the dianions (14a) and (14c) which are sufficiently stable at <= -90 deg C to be trapped by aldehydes.The dianion (14b) derived from 6-methoxybenzofuran-2-carboxylic acid (13b), however, suffers rapid ring opening before it can be trapped, even at very low temperatures.A plausible explanation of these observations is given.Metallation of 3-methylbenzofuran-2-carboxylic acid (18) affords the dianion (20), which cannot undergo ring opening and which is a valuable intermediate for the synthesis of a range of 3-substituted benzofuran-2-carboxylic acids. A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 24673-56-1 Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2726O – PubChem