Recommanded Product: 129-18-0. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide, is researched, Molecular C19H19N2NaO2, CAS is 129-18-0, about Modification of the cardiac activity of digoxin by phenylbutazone and sodium salicylate. Author is Ammar, Elsayed M.; Elakkad, Ibrahim N.; Elbitar, Hussein H..
Daily oral treatment with the phenylbutazone-Na [129-18-0] or Na salicylate [54-21-7] for 2 weeks decreased the cardiac activity of digoxin (I) [20830-75-5], as indicated by an increase in its lethal dose in guinea pigs. The uptake of I by ventricular strips from rabbits, pretreated with phenylbutazone or sodium salicylate, was decreased, and this decrease may explain its decreased cardiac activity. Competition between the 2 antirheumatic drugs and I is discussed at both the plasma protein and the cardiac tissue levels. Thus, drug interactions and the subsequent decreased clinical effectiveness of I occur when I is prescribed in combination with phenylbutazone or sodium salicylate.
After consulting a lot of data, we found that this compound(129-18-0)Recommanded Product: 129-18-0 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem