Month: November 2021

In 2020 PESTIC BIOCHEM PHYS published article about STRUCTURE-BASED DESIGN; ACARICIDAL ACTIVITY; CNIDIUM-OFFICINALE; PLANTS; BUTYLIDENEPHTHALIDE; TOXICITY; MELANIN; PROPHENOLOXIDASE; DERIVATIVES; INHIBITION in [Abbod, Mohsen; Safaie, Naser] Tarbiat Modares Univ, Fac Agr, Dept Plant Pathol, POB 14115-336, Tehran, Iran; [Gholivand, Khodayar; Bonsaii, Mahyar] Tarbiat Modares Univ, Dept Chem, POB 14115-175, Tehran, Iran; [Mehrabadi, Mohammad] Tarbiat Modares Univ, Fac Agr, Dept Entomol, POB 14115-336, Tehran, Iran in 2020, Cited 64. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. HPLC of Formula: C8H6O2

In this study, the biological activities and mode of action of 3-butylidene phthalide (3-BPH) were studied. 3-BPH had a superior efficiency against microsclerotia of Macrophomina phaseolina compared to the commercial fungicide tricyclazole. The microsclerotia formation and pigmentation were inhibited at 100 mu g/mL. Moreover, the fungicide exhibited in silico affinity toward trihydroxy naphthalene reductase (3HNR). Both 3-BPH and tricyclazole showed congruence in the orientation and interaction within the 3HNR active site. 3-BPH displayed a strong interaction with SER-164, TYR-178, and TYR-223, with estimated binding energy and inhibition constant of -6.78 kcal mol(-1), and Ki = 12.6 mu M, respectively. Furthermore, it showed in vitro and in silico inhibitory activity against Drosophila melanogaster acetylcholinesterase in a concentration-dependent manner with IC50 = 730 mu g/mL. It also impaired Galleria mellonella phenol oxidase enzyme, which corresponds with the insect’s immune system. Phytotoxicity of 3-BPH was evident against Lemna minor at 1000 mu g/mL; nevertheless, it was nontoxic at the concentrations inhibiting M. phaseolina microsclerotia and dark pigments suggest that it may be safe for use on other plants at low doses. Further assays are wanted to develop 3-BPH as a novel crop protection compound.

HPLC of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Abbod, M; Safaie, N; Gholivand, K; Mehrabadi, M; Bonsaii, M or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Safety of Isobenzofuran-1(3H)-one. I found the field of Pharmacology & Pharmacy very interesting. Saw the article SYNTHESIS AND EVALUATION OF THE ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF NOVEL DIBENZOTHIEPINES published in 2020, Reprint Addresses Pircalabioru, GG (corresponding author), Univ Bucharest, Res Inst, Bucharest 60101, Romania.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

Considering the anti-infective potential of compounds containing the dibenzothiepine scaffold, we set out to obtain new compounds bearing this structure. The synthesized compounds were characterized by spectral studies and elemental analysis and screened for their microbiostatic/microbicidal and antibiofilm properties against reference and clinical microbial strains. The new compounds exhibited a broad spectrum of antimicrobial activity, which was more intensive for the S-oxidized compounds. Some of the compounds also inhibited the ability of the investigated strains to form biofilms on the inert substratum.

Safety of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Stecoza, CE; Draghici, C; Caproiu, MT; Pircalabioru, GG; Marutescu, L or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

COA of Formula: C8H6O2. Authors Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN in ROYAL SOC CHEMISTRY published article about in [Rumyantsev, Andrey, V; Pichugov, Andrey, V; Bushkov, Nikolai S.; Aleshin, Dmitry Yu; Strelkova, Tatyana, V; Lependina, Olga L.; Zhizhko, Pavel A.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Rumyantsev, Andrey, V; Bushkov, Nikolai S.] Moscow MV Lomonosov State Univ, Dept Chem, Vorobevy Gory 1, Moscow 119991, Russia; [Pichugov, Andrey, V; Aleshin, Dmitry Yu] D Mendeleev Univ Chem Technol Russia, Higher Chem Coll, Miusskaya Sq 9, Moscow 125047, Russia in 2021, Cited 33. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

We report the first examples of direct imidation of lactones giving the corresponding cyclic imidates via oxo/imido heterometathesis with N-sulfinylamines catalysed by a well-defined silica-supported Ti imido complex.

COA of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Quality Control of Isobenzofuran-1(3H)-one. In 2020 CHEM ENG J published article about TM-DOPED TIO2; UP-CONVERSION; GAS-PHASE; CATALYTIC-OXIDATION; OPTICAL-PROPERTIES; FACILE SYNTHESIS; ANATASE TIO2; TOLUENE; NANOPARTICLES; NANOTUBES in [Rao, Zepeng; Shi, Gansheng; Wang, Zhuang; Mahmood, Asad; Xie, Xiaofeng; Sun, Jing] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China; [Rao, Zepeng] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China in 2020, Cited 59. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

In this work, we synthesized thulium (Tm3+) modified TiO2 nanoparticles by a facile sol-gel route. We show that Tm3+-modified TiO2 exhibit superior photocatalytic activity than pure TiO2 towards gas-phase degradation of acetaldehyde, o-xylene, and their mixture. The photocatalytic activity enhances with the increasing Tm content from 0.1 to 0.5 mol%. The 0.5 mol%Tm-TiO2 sample demonstrated the highest photodegradation efficiency (> 90.0%) for acetaldehyde and o-xylene. According to the systematic characterization such as photoluminescence (PL), photocurrent, up-conversion spectra, UV-Vis diffuse reflectance spectroscopy and electron spin resonance (ESR) analysis, the enhanced photocatalytic performance can be attributed to introducing the new Tm-4f states between the original band gap of TiO2, which led to the increase of efficiency of light-induced electron-hole separation and the increase of hydrophilicity which resulted in the increased adsorption capacity towards acetaldehyde and o-xylene. Gas Chromatography-Mass Spectrometer (GC-MS) analysis suggested that o-xylene was first oxidized to o-benzaldehyde, which was eventually converted to butanol before being mineralized into CO2. However, new intermediates including phthalide, o-methyl acetophenone, naphthalene and 5-Methyl-4-octanone were detected in the mixture.

Quality Control of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Rao, ZP; Shi, GS; Wang, Z; Mahmood, A; Xie, XF; Sun, J or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Product Details of 87-41-2. In 2020 CHEM ENG J published article about TM-DOPED TIO2; UP-CONVERSION; GAS-PHASE; CATALYTIC-OXIDATION; OPTICAL-PROPERTIES; FACILE SYNTHESIS; ANATASE TIO2; TOLUENE; NANOPARTICLES; NANOTUBES in [Rao, Zepeng; Shi, Gansheng; Wang, Zhuang; Mahmood, Asad; Xie, Xiaofeng; Sun, Jing] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China; [Rao, Zepeng] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China in 2020, Cited 59. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

In this work, we synthesized thulium (Tm3+) modified TiO2 nanoparticles by a facile sol-gel route. We show that Tm3+-modified TiO2 exhibit superior photocatalytic activity than pure TiO2 towards gas-phase degradation of acetaldehyde, o-xylene, and their mixture. The photocatalytic activity enhances with the increasing Tm content from 0.1 to 0.5 mol%. The 0.5 mol%Tm-TiO2 sample demonstrated the highest photodegradation efficiency (> 90.0%) for acetaldehyde and o-xylene. According to the systematic characterization such as photoluminescence (PL), photocurrent, up-conversion spectra, UV-Vis diffuse reflectance spectroscopy and electron spin resonance (ESR) analysis, the enhanced photocatalytic performance can be attributed to introducing the new Tm-4f states between the original band gap of TiO2, which led to the increase of efficiency of light-induced electron-hole separation and the increase of hydrophilicity which resulted in the increased adsorption capacity towards acetaldehyde and o-xylene. Gas Chromatography-Mass Spectrometer (GC-MS) analysis suggested that o-xylene was first oxidized to o-benzaldehyde, which was eventually converted to butanol before being mineralized into CO2. However, new intermediates including phthalide, o-methyl acetophenone, naphthalene and 5-Methyl-4-octanone were detected in the mixture.

Product Details of 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Rao, ZP; Shi, GS; Wang, Z; Mahmood, A; Xie, XF; Sun, J or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Nozawa-Kumada, K; Kurosu, S; Shigeno, M; Kondo, Y in [Nozawa-Kumada, Kanako; Kurosu, Satoshi; Shigeno, Masanori; Kondo, Yoshinori] Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, 6-3 Aoba, Sendai, Miyagi 9808578, Japan published Peroxydisulfate-Mediated Transition-Metal-Free Oxidative C(sp(3))-H Bond Lactonization in 2019, Cited 48. Application In Synthesis of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

An inexpensive, powerful, and eco-friendly method for transition-metal-free oxidative C(sp(3))-H bond lactonization was developed using sodium peroxydisulfate as the sole oxidant. The cyclization of 2-alkylbenzoic acids containing a primary, secondary or tertiary carbon at the benzylic position proceeded smoothly, affording a variety of lactone derivatives. Furthermore, various functional groups such as halogen, cyano, nitro and hydroxy groups were tolerated under the reaction conditions.

Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Nozawa-Kumada, K; Kurosu, S; Shigeno, M; Kondo, Y or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2020 ANGEW CHEM INT EDIT published article about CHANNEL ORGANIC SEMICONDUCTORS; PI-CONJUGATED MATERIALS; HIGH-PERFORMANCE; BUILDING-BLOCK; THIOPHENE-S,S-DIOXIDIZED INDOPHENINE; QUINOIDAL OLIGOTHIOPHENES; SIDE-CHAIN; MOLECULES; POLYMERS; ANALOGS in [Du, Tian; Gao, Ruiheng; Deng, Yunfeng; Wang, Cheng; Zhou, Qian; Geng, Yanhou] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China; [Deng, Yunfeng; Geng, Yanhou] Tianjin Univ, Tianjin Key Lab Mol Optoelect Sci, Tianjin 300072, Peoples R China; [Deng, Yunfeng; Geng, Yanhou] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China; [Geng, Yanhou] Tianjin Univ, Joint Sch Natl Univ Singapore & Tianjin Univ, Int Campus, Fuzhou 350207, Fujian, Peoples R China in 2020, Cited 46. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. COA of Formula: C8H6O2

A series of 1,3-indandione-terminated pi-conjugated quinoids were synthesized by alkoxide-mediated rearrangement reaction of the respective alkene precursors, followed by air oxidation. This new protocol allows access to quinoidal compounds with variable termini and cores. The resulting quinoids all show LUMO levels below -4.0 eV and molar extinction coefficients above 10(5) L mol(-1) cm(-1). The optoelectronic properties of these compounds can be regulated by tuning the central cores as well as the aryl termini ascribed to the delocalized frontier molecular orbitals over the entire molecular skeleton involving aryl termini. n-Channel organic thin-film transistors with electron mobility of up to 0.38 cm(2) V-1 s(-1) were fabricated, showing the potential of this new class of quinoids as organic semiconductors.

COA of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Du, T; Gao, RH; Deng, YF; Wang, C; Zhou, Q; Geng, YH or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

I found the field of Chemistry; Science & Technology – Other Topics very interesting. Saw the article Continuous-Flow Amide and Ester Reductions Using Neat Borane Dimethylsulfide Complex published in 2020. Safety of Isobenzofuran-1(3H)-one, Reprint Addresses Otvos, SB; Kappe, CO (corresponding author), Karl Franzens Univ Graz, Inst Chem, NAWI Graz, Heinrichstr 28, A-8010 Graz, Austria.; Kappe, CO (corresponding author), RCPE, Ctr Continuous Synth & Proc CCFLOW, Inffeldgasse 13, A-8010 Graz, Austria.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Reductions of amides and esters are of critical importance in synthetic chemistry, and there are numerous protocols for executing these transformations employing traditional batch conditions. Notably, strategies based on flow chemistry, especially for amide reductions, are much less explored. Herein, a simple process was developed in which neat borane dimethylsulfide complex (BH3 center dot DMS) was used to reduce various esters and amides under continuous-flow conditions. Taking advantage of the solvent-free nature of the commercially available borane reagent, high substrate concentrations were realized, allowing outstanding productivity and a significant reduction in E-factors. In addition, with carefully optimized short residence times, the corresponding alcohols and amines were obtained in high selectivity and high yields. The synthetic utility of the inexpensive and easily implemented flow protocol was further corroborated by multigram-scale syntheses of pharmaceutically relevant products. Owing to its beneficial features, including low solvent and reducing agent consumption, high selectivity, simplicity, and inherent scalability, the present process demonstrates fewer environmental concerns than most typical batch reductions using metal hydrides as reducing agents.

Safety of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Otvos, SB; Kappe, CO or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

SDS of cas: 87-41-2. Recently I am researching about ASYMMETRIC BINARY ACID; 3-SUBSTITUTED PHTHALIDES; TRANSFER HYDROGENATION; RELAY CATALYSIS; TRANSFORMATION; DERIVATIVES; FUSCINARIN; CHEMISTRY; ACETALS; ETHERS, Saw an article supported by the NNSFCNational Natural Science Foundation of China (NSFC) [21971120, 21933008]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Pan, YL; Zheng, HL; Wang, J; Yang, C; Li, X; Cheng, JP. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Phthalides as the crucial core skeletons are found extensively in natural products and biological active molecules. Herein we disclose an asymmetric allylation of 3-hydroxyisoben-zofuran-1(3H)-ones with boron allylation reagents to construct chiral phthalide derivatives. The simple Bi(OAc)(3)/chiral phosphoric acid catalytic system proves to be efficient in this method, delivering the desired chiral 3-allylisobenzofuran-1(3H)-ones in good yields (up to 99%) and high enantioselectivities (up to 99.5:0.5 e.r.) under mild conditions. The large-scale reaction and diverse transformations of products to various scaffolds with potential biological activities render it more attractive. Moreover, the mechanism was preliminarily explored by control reactions, mass spectrometry, deuterium experiment, and DFT calculations.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Pan, YL; Zheng, HL; Wang, J; Yang, C; Li, X; Cheng, JP or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

COA of Formula: C8H6O2. Tzirakis, MD; Malliaros, NG; Orfanopoulos, M in [Tzirakis, Manolis D.; Malliaros, Nikitas G.; Orfanopoulos, Michael] Univ Crete, Dept Chem, Voutes Campus, Iraklion 71003, Crete, Greece published Photochemical Reaction of o-Phthalaldehyde with Fullerene C-60: The Stimulus for the Phthalide Additions to C-60 in 2019, Cited 18. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

A new, simple, and rapid photochemical reaction of o-phthalaldehyde with C-60 has been disclosed. This reaction afforded exclusively the unanticipated C-60-phthalide derivative 11 in good yield. The formation of this product is consistent with the intervention of a key free-radical intermediate -a benzylic radical- in the course of the reaction. The structure of 11 has been determined by the combined use of experimental and theoretical NMR studies. In the course of this study we further disclosed a new mode of radical reactivity of C-60 with a series of substituted phthalides (2, 15-17) catalyzed by tetrabutylammonium decatungstate.

COA of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Tzirakis, MD; Malliaros, NG; Orfanopoulos, M or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem