Chemistry can be defined as the study of matter and the changes it undergoes. 27550-59-0. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.27550-59-0, Name is 5-Hydroxyisobenzofuran-1,3-dione, molecular formula is C8H4O4, introducing its new discovery.
Syntheses of aromatic substituted 6?-thiothalidomides
A resurgence of interest in thalidomide has occurred as a consequence of its diverse immunomodulatory and anticancer actions, which has fuelled interest in synthetic analogues with higher potencies or less undesirable side effect profiles. Several novel aromatic substituted 6?-thiothalidomides were synthesized whose synthetic route and strategy were developed on the basis of an analysis of reaction mechanisms. The regioselectivity of mono-thionation of aromatic substituted thalidomides with Lawesson’s reagent is described, and the chemoselectivity of hydrogenation between the nitro group and 6?-thiocarbonyl group is discussed. Full characterization of eight substituted 6?-thiothalidomides is reported. Georg Thieme Verlag Stuttgart.
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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2151O – PubChem