The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide( cas:129-18-0 ) is researched.Application of 129-18-0.Pawelczyk, Ewaryst; Wachowiak, Roman published the article 《Kinetics of drug decomposition. VII. Kinetics of sodium phenylbutazone hydrolysis》 about this compound( cas:129-18-0 ) in Dissertationes Pharmaceuticae et Pharmacologicae. Keywords: phenylbutazone decomposition kinetics; kinetics decomposition phenylbutazone; hydrolysis phenylbutazone. Let’s learn more about this compound (cas:129-18-0).
The decomposition rate of 0.00303M Na phenylbutazone (I) in aqueous buffer under N was 1st order. The rate was independent of kind and concentration of buffer, its ionic strength, and hydroxyl ion activity. Storage of a 20% aqueous solution of I at 20° produces a decomposition loss of 10% after 1.047 years. Concentrations of I were determined spectrophotometrically using measurements at 235 and 264 nm.
As far as I know, this compound(129-18-0)Application of 129-18-0 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem