Decarboxylative tandem C-N coupling with nitroarenes via SH2 mechanism was written by Wang, Shuaishuai;Li, Tingrui;Gu, Chengyihan;Han, Jie;Zhao, Chuan-Gang;Zhu, Chengjian;Tan, Hairen;Xie, Jin. And the article was included in Nature Communications in 2022.Recommanded Product: 17403-47-3 This article mentions the following:
In this paper, a radical tandem C-N coupling strategy to efficiently construct aromatic tertiary amines from com. available carboxylic acids and nitroarenes was developed. A variety of aromatic tertiary amines were furnished in good yields (up to 98%) with excellent functional group compatibility under mild reaction conditions. The use of two different carboxylic acids also allowed for the concise synthesis of nonsym. aromatic tertiary amines in satisfactory yields. Mechanistic studies suggested the intermediacy of the arylamine-(TPP)Fe(III) species and might provide a possible evidence for an SH2 (bimol. homolytic substitution) pathway in the critical C-N bond formation step. In the experiment, the researchers used many compounds, for example, 5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3Recommanded Product: 17403-47-3).
5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 17403-47-3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem