Tag: 165.15

Gu, Ling-Hui et al. published their research in Tetrahedron in 2014 | CAS: 17403-47-3

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Application In Synthesis of 5-Nitro-2,3-dihydrobenzofuran

A mild and efficient amidation of cyclic ethers catalyzed by rhodium caprylate was written by Gu, Ling-Hui;Zhang, Dan-Dan;Qi, Qing-Rong;Yin, Ping;He, Ling. And the article was included in Tetrahedron in 2014.Application In Synthesis of 5-Nitro-2,3-dihydrobenzofuran This article mentions the following:

A small quantity of Rh2(O2CC7H15)4 catalyzed the α-amidation of cyclic ethers under mild conditions, in the presence of electron-withdrawing p-chlorobenzenesulfonamide/PhI(OAc)2 as the nitrene source, in CH2Cl2. The corresponding N-substituted amino cyclic ethers were successfully obtained in good yields, e.g., I, and compatibility with other oxidant sensitive structures in one-pot reaction. In the experiment, the researchers used many compounds, for example, 5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3Application In Synthesis of 5-Nitro-2,3-dihydrobenzofuran).

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Application In Synthesis of 5-Nitro-2,3-dihydrobenzofuran

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Wang, Shuaishuai et al. published their research in Nature Communications in 2022 | CAS: 17403-47-3

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 17403-47-3

Decarboxylative tandem C-N coupling with nitroarenes via SH2 mechanism was written by Wang, Shuaishuai;Li, Tingrui;Gu, Chengyihan;Han, Jie;Zhao, Chuan-Gang;Zhu, Chengjian;Tan, Hairen;Xie, Jin. And the article was included in Nature Communications in 2022.Recommanded Product: 17403-47-3 This article mentions the following:

In this paper, a radical tandem C-N coupling strategy to efficiently construct aromatic tertiary amines from com. available carboxylic acids and nitroarenes was developed. A variety of aromatic tertiary amines were furnished in good yields (up to 98%) with excellent functional group compatibility under mild reaction conditions. The use of two different carboxylic acids also allowed for the concise synthesis of nonsym. aromatic tertiary amines in satisfactory yields. Mechanistic studies suggested the intermediacy of the arylamine-(TPP)Fe(III) species and might provide a possible evidence for an SH2 (bimol. homolytic substitution) pathway in the critical C-N bond formation step. In the experiment, the researchers used many compounds, for example, 5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3Recommanded Product: 17403-47-3).

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 17403-47-3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Wang, Shuaishuai et al. published their research in Nature Communications in 2022 | CAS: 17403-47-3

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 17403-47-3

Decarboxylative tandem C-N coupling with nitroarenes via SH2 mechanism was written by Wang, Shuaishuai;Li, Tingrui;Gu, Chengyihan;Han, Jie;Zhao, Chuan-Gang;Zhu, Chengjian;Tan, Hairen;Xie, Jin. And the article was included in Nature Communications in 2022.Recommanded Product: 17403-47-3 This article mentions the following:

In this paper, a radical tandem C-N coupling strategy to efficiently construct aromatic tertiary amines from com. available carboxylic acids and nitroarenes was developed. A variety of aromatic tertiary amines were furnished in good yields (up to 98%) with excellent functional group compatibility under mild reaction conditions. The use of two different carboxylic acids also allowed for the concise synthesis of nonsym. aromatic tertiary amines in satisfactory yields. Mechanistic studies suggested the intermediacy of the arylamine-(TPP)Fe(III) species and might provide a possible evidence for an SH2 (bimol. homolytic substitution) pathway in the critical C-N bond formation step. In the experiment, the researchers used many compounds, for example, 5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3Recommanded Product: 17403-47-3).

5-Nitro-2,3-dihydrobenzofuran (cas: 17403-47-3) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: 17403-47-3

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem