Santaniello, Enzo; Ferraboschi, Patrizia; Grisenti, Paride; Manzocchi, Ada; Trave, Susanna published an article about the compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate( cas:90866-33-4,SMILESS:O=C(OCC)C[C@@H](O)CCl ).Safety of (R)-Ethyl 4-chloro-3-hydroxybutanoate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:90866-33-4) through the article.
At 25°, the pig liver esterase-catalyzed hydrolyses of RCH(OR1)CH2CO2Et (I; R = Ph, CH2Cl; R1 = H) proceed in aqueous phosphate buffer with moderate enantioselectivity, which is increased in 20% aqueous EtOH. When the hydroxy group is protected as acetate, the enantioselectivity of the enzymic reaction in water is generally improved, but cleavage of the acetoxy group competes with hydrolysis of the alkoxycarbonyl moiety. In 20% aqueous EtOH the acetoxy group of I (R = Ph, CH2Cl; R1 = Ac) is preferentially hydrolyzed, and the enantiomeric excess reaches 52-90%.
In addition to the literature in the link below, there is a lot of literature about this compound((R)-Ethyl 4-chloro-3-hydroxybutanoate)Safety of (R)-Ethyl 4-chloro-3-hydroxybutanoate, illustrating the importance and wide applicability of this compound(90866-33-4).
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem