The important role of 3199-61-9

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3199-61-9, Name is Ethyl benzofuran-2-carboxylate, belongs to benzofurans compound, is a common compound. Formula: C11H10O3In an article, once mentioned the new application about 3199-61-9.

The Roessing’s reaction of 4-substituted 2-acylphenoxyacetic acids give a mixture of benzofurans and 2-benzofurancarboxylic acids. The relative yields of benzofurans and 2-benzofurancarboxylic acids depend on the substituents on the benzene ring of the 2-acylphenoxyacetic acids. Electron-withdrawing substituents such as nitro groups favor the formation of 2-benzofurancarboxylic acids. On the other hand, the formation of benzofurans is favored by the steric hindrance of 2-acyl groups in the reaction of 2-acyl-4-nitrophenoxyacetic acids with anhydrous sodium acetate and acetic anhydride.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3052O – PubChem